Trend in blood lead levels in Taiwanese adults 2005–2017

This study examined the trend of blood lead levels (BLLs) in Taiwanese adults and analyzed the variations in the BLL between Linkou (northern) and Kaohsiung (southern) hospital branches. Between 2005 and 2017, 3,804 adult participants received blood lead tests at the Linkou (n = 2,674) and Kaohsiung (n = 1,130) branches of Chang Gung Memorial Hospital. The geometric mean of BLL was 2.77 μg/dL. The adult participants from the Kaohsiung branch were not only age older (49.8±14.1 versus 39.4±14.2 years; P<0.001) and male predominant (65.8 versus 41.7%; P<0.001) but also showed a higher BLL (4.45±3.93 versus 2.82±2.42 μg/dL; P<0.001) and lower estimated glomerular filtration rate (87.62±25.94 versus 93.67±23.88; P<0.001) than those from the Linkou branch. Multivariable logistic regression analysis revealed that the Kaohsiung branch [odds ratio (OR): 7.143; 95% confident interval (CI): 5.682–8.929; P<0.001], older age (OR: 1.008; 95% CI: 1.000–1.015; P = 0.043) and reduced estimated glomerular filtration rate (OR: 1.009; 95% CI: 1.004–1.014; P = 0.001) were significant predictors for BLL > 5 μg/dL. Therefore, this study confirmed a continuous decreasing trend in the BLL in Taiwan after banning leaded petrol in 2000.

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Prenatal blood lead levels and reduced preadolescent glomerular filtration rate: Modification by body mass index

Environment International ◽

10.1016/j.envint.2021.106414 ◽

2021 ◽

pp. 106414

Author(s):

Charlie Saylor ◽

Marcela Tamayo-Ortiz ◽

Ivan Pantic ◽

Chitra Amarasiriwardena ◽

Nia McRae ◽

...

Keyword(s):

Body Mass Index ◽

Glomerular Filtration Rate ◽

Glomerular Filtration ◽

Body Mass ◽

Filtration Rate ◽

Blood Lead ◽

Blood Lead Levels ◽

Lead Levels

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Associations of blood lead, cadmium, and mercury with estimated glomerular filtration rate in the Korean general population: Analysis of 2008–2010 Korean National Health and Nutrition Examination Survey data

Environmental Research ◽

10.1016/j.envres.2012.06.003 ◽

2012 ◽

Vol 118 ◽

pp. 124-129 ◽

Cited By ~ 49

Author(s):

Yangho Kim ◽

Byung-Kook Lee

Keyword(s):

Glomerular Filtration Rate ◽

General Population ◽

Glomerular Filtration ◽

Survey Data ◽

Filtration Rate ◽

Estimated Glomerular Filtration Rate ◽

Population Analysis ◽

Blood Lead ◽

Nutrition Examination Survey ◽

Health And Nutrition

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Associations of blood lead with estimated glomerular filtration rate using MDRD, CKD-EPI and serum cystatin C-based equations

Nephrology Dialysis Transplantation ◽

10.1093/ndt/gfq773 ◽

2011 ◽

Vol 26 (9) ◽

pp. 2786-2792 ◽

Cited By ~ 24

Author(s):

J. T. Spector ◽

A. Navas-Acien ◽

J. Fadrowski ◽

E. Guallar ◽

B. Jaar ◽

...

Keyword(s):

Glomerular Filtration Rate ◽

Glomerular Filtration ◽

Cystatin C ◽

Filtration Rate ◽

Estimated Glomerular Filtration Rate ◽

Blood Lead ◽

Serum Cystatin C ◽

Serum Cystatin

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Association of thyroid function with estimated glomerular filtration rate in a population-based study: the HUNT study

Acta Endocrinologica ◽

10.1530/eje-10-0705e ◽

2011 ◽

Vol 164 (2) ◽

pp. 316

Author(s):

Bjørn Olav Åsvold ◽

Trine Bjøro ◽

Lars J Vatten

Keyword(s):

Glomerular Filtration Rate ◽

Glomerular Filtration ◽

Thyroid Function ◽

Filtration Rate ◽

Estimated Glomerular Filtration Rate ◽

Geometric Mean ◽

Population Based ◽

Population Based Study ◽

Article Type ◽

Hunt Study

The journal and the authors apologise for an error in this article published in the European Journal of Endocrinology (2011) 164 101–105. The caption to Table 4 on page 104 was wrongly printed and the correct caption and table is printed in full below.Table 4Geometric mean eGFR (ml/min per 1.73 m2) by categories of thyroid function and age, adjusted for sex, age and smoking.Age <70 years (n=22 071)Age ≥70 years (n=7409)eGFR95% CIeGFR95% CIHyperthyroidismOvert120.5113.5128.087.078.996.0Subclinical91.789.993.476.473.479.5TSH (mU/l)0.50–1.489.989.690.375.374.476.21.5–2.488.588.188.973.572.674.42.5–3.587.086.387.772.671.473.8HypothyroidismSubclinical86.585.587.470.769.372.2Overt83.380.586.468.363.373.6

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Association of glomerular filtration rate slope with timely creation of vascular access in incident hemodialysis

Scientific Reports ◽

10.1038/s41598-021-92359-w ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Lee-Moay Lim ◽

Ming-Yen Lin ◽

Shang-Jyh Hwang ◽

Hung-Chun Chen ◽

Yi-Wen Chiu

Keyword(s):

Glomerular Filtration Rate ◽

Glomerular Filtration ◽

Vascular Access ◽

Filtration Rate ◽

Estimated Glomerular Filtration Rate ◽

Care Program ◽

Multidisciplinary Care ◽

Multivariable Logistic Regression Analysis ◽

Shaped Pattern ◽

Egfr Slope

AbstractThe factors associated with the timely creation of distal vascular access for hemodialysis initiation are unclear. We aimed to explore the association between the slope of estimated glomerular filtration rate (eGFR) and the successful usage of vascular access upon hemodialysis initiation. This single center retrospective cohort study enrolled chronic kidney disease patients who undertook a multidisciplinary care program from 2003 to 2016. Using eGFR slope as predictor, we evaluated the vascular access created timely upon hemodialysis initiation. Among the 987 patients, vascular access was created at a median eGFR of 5.8 min/ml/1.73 m2, with a median duration of 3.1 months before hemodialysis. The proportions of vascular access created timely, created not timely (vascular access immature), and not created were 68.5%, 8.8%, and 22.7%, respectively. There was a significant negative association of eGFR upon vascular access creation with eGFR slope (r = − 0.182, P < 0.001). The fastest eGFR slope patients (the first quartile or < − 10 min/ml/1.73 m2/year) had the lowest percentage of vascular access created timely. In the multivariable logistic regression analysis, only higher eGFR upon vascular access creation (P = 0.001) and eGFR slope (P = 0.009) were significantly associated with vascular access created timely. The adjusted odds ratios of each quartile of eGFR slopes for vascular access created timely were 0.46 (95% confidence interval 0.27–0.86), 1.30 (0.62, 2.72), 1.00 (reference), and 0.95 (0.48–1.87), respectively. eGFR slope is associated with the timely creation of vascular access for the initiation of hemodialysis in a reverse-J-shaped pattern and may help determine the time of vascular access creation.

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Effects of Estimated Glomerular Filtration Rate on Clinical Outcomes in Patients with Intracerebral Hemorrhage

10.21203/rs.3.rs-844881/v1 ◽

2021 ◽

Author(s):

zhaoxia Li ◽

Zixiao Li ◽

Qi Zhou ◽

Hongqiu Gu ◽

Yongjun Wang ◽

...

Keyword(s):

Glomerular Filtration Rate ◽

Intracerebral Hemorrhage ◽

Hospital Mortality ◽

Glomerular Filtration ◽

Filtration Rate ◽

Estimated Glomerular Filtration Rate ◽

Multivariable Logistic Regression Analysis ◽

Stroke Severity ◽

Hematoma Evacuation ◽

Increased Risk

Abstract Background: The influence of chronic kidney disease (CKD) on severity and prognosis of spontaneous intracerebral hemorrhage (ICH) is scarcely investigated. We aimed to explore the association of admission estimated glomerular filtration rate (eGFR) levels with stroke severity and outcomes in ICH patients.Materials and Methods: The patients enrolled in this study were from the China Stroke Center Alliance study (CSCA). Patients were divided into four groups according to different admission eGFR levels (≥90;60-89;45-59;<45). Multivariable logistic regression analysis was used to determine the association of admission eGFR levels with stroke severity, in-hospital complications, discharge deposition, and in-hospital mortality after ICH.Results: 85167 patients with acute ICH were included in the present analysis. Among them, 9493 (11.1%) had baseline eGFR＜60 ml/min/1.73 m2. Low eGFR was associated with increasing risk of in-hospital mortality [eGFR 60-89 ml/min/1.73 m2, odds ratios(OR) 2.07(95% confidence interval(CI) 0.45 -9.4); eGFR 45-59, 8.43 (1.15- 61.98); eGFR＜45, 13.92 (2.22 - 87.15); P for trend < 0.0001]after adjusting for the confounding factors. With the declining of eGFR, the risk of non-routine disposition and hematoma evacuation increased in patients with eGFR 45 to 59 ml/min/1.73 m2(OR 8.43; 95%CI 1.15-61.98 and OR 3.36; 95% CI 1.2-9.44, respectively). No significant association between different level of eGFR at baseline and stroke severity, in-hospital complication such as pneumonia, hydrocephalus, rebleeding were observed.Conclusions: Low eGFR at baseline was associated with increased risk of in-hospital mortality, non-routine disposition and hematoma evacuation but not with stroke severity and in-hospital complications in acute ICH patients.

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