scholarly journals Association of thyroid function with estimated glomerular filtration rate in a population-based study: the HUNT study

2011 ◽  
Vol 164 (2) ◽  
pp. 316
Author(s):  
Bjørn Olav Åsvold ◽  
Trine Bjøro ◽  
Lars J Vatten
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Thyroid Function ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Geometric Mean ◽  
Population Based ◽  
Population Based Study ◽  
Article Type ◽  
Hunt Study

The journal and the authors apologise for an error in this article published in the European Journal of Endocrinology (2011) 164 101–105. The caption to Table 4 on page 104 was wrongly printed and the correct caption and table is printed in full below.Table 4Geometric mean eGFR (ml/min per 1.73 m2) by categories of thyroid function and age, adjusted for sex, age and smoking.Age <70 years (n=22 071)Age ≥70 years (n=7409)eGFR95% CIeGFR95% CIHyperthyroidismOvert120.5113.5128.087.078.996.0Subclinical91.789.993.476.473.479.5TSH (mU/l)0.50–1.489.989.690.375.374.476.21.5–2.488.588.188.973.572.674.42.5–3.587.086.387.772.671.473.8HypothyroidismSubclinical86.585.587.470.769.372.2Overt83.380.586.468.363.373.6

scholarly journals Association of thyroid function with estimated glomerular filtration rate in a population-based study: the HUNT study

2011 ◽  
Vol 164 (1) ◽  
pp. 101-105 ◽  
Author(s):  
Bjørn Olav Åsvold ◽  
Trine Bjøro ◽  
Lars J Vatten
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Thyroid Function ◽  
Filtration Rate ◽  
Reference Range ◽  
Reference Group ◽  
Geometric Mean ◽  
Population Based ◽  
Overt Hypothyroidism ◽  
Population Based Study

ObjectiveLow thyroid function may be associated with reduced glomerular filtration rate (GFR). We therefore studied the association of thyroid function with estimated GFR (eGFR) in a population-based study.DesignA cross-sectional, population-based study of 29 480 individuals above 40 years of age, without previously known thyroid disease.MethodsWe calculated geometric mean eGFR and odds ratio (OR) of chronic kidney disease (CKD; eGFR <60 ml/min per 1.73 m2) according to categories of thyroid function, using people with TSH in the lower third of the reference range (0.50–1.4 mU/l) as the comparison group.ResultsTSH within the reference range (0.50–3.5 mU/l) was negatively associated with eGFR (P for trend <0.001). Compared with people with TSH in the lower third of the reference range (83.0 ml/min per 1.73 m2), eGFR was lower in people with TSH in the middle (81.6 ml/min per 1.73 m2) and highest third (80.3 ml/min per 1.73 m2) of the reference range, and in people with subclinical (79.3 ml/min per 1.73 m2, P<0.001) or overt hypothyroidism (76.5 ml/min per 1.73 m2, P<0.001). The prevalence of CKD was higher in people with TSH in the middle (OR 1.20, 95% confidence interval (CI) 1.07–1.35) or highest third (OR 1.31, 95% CI 1.13–1.52) of the reference range, compared with people in the reference group. Also, CKD was more common in people with subclinical (OR 1.63, 95% CI 1.38–1.93) or overt (OR 1.98, 95% CI 1.22–3.20) hypothyroidism.ConclusionsThese findings suggest that low thyroid function, also within the clinically normal range, is associated with reduced GFR.

The effects of protein intake on albuminuria in different estimated glomerular filtration rate: A population-based study

2018 ◽  
Vol 48 ◽  
pp. 80-88
Author(s):  
Yan Liu ◽  
Rong-shao Tan ◽  
Dao-yuan Zhou ◽  
Xiao Xiao ◽  
Jian-min Ran ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Protein Intake ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Population Based ◽  
Population Based Study

scholarly journals Self-reported sleep duration is associated with reduced glomerular filtration rate among adults with hypertension: a population-based study from rural northeast China

2015 ◽  
Vol 24 (3) ◽  
pp. 351-358 ◽  
Author(s):  
Xiaofan Guo ◽  
Shasha Yu ◽  
Zhao Li ◽  
Liang Guo ◽  
Liqiang Zheng ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Sleep Duration ◽  
Northeast China ◽  
Filtration Rate ◽  
Population Based ◽  
Population Based Study

Relationship Between Metabolic Syndrome Severity and Kidney Function as Related to Gender: A Population-Based Longitudinal Study

2018 ◽  
Vol 29 (6) ◽  
pp. 355-362 ◽  
Author(s):  
Sheng-Pyng Chen ◽  
Chi-Rong Li ◽  
Huan-Cheng Chang ◽  
Yu-Ling Li ◽  
Hsiang-Chu Pai
Keyword(s):  
Metabolic Syndrome ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Kidney Function ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Population Based ◽  
Health Examination ◽  
Z Score ◽  
The Metabolic Syndrome

The purpose of this study was to explore the relationship between the metabolic syndrome severity Z-score and kidney function by gender. We also examined the estimated glomerular filtration rate in relation to other known risk factors. The study used was a population-based prospective longitudinal research design. A total of 4,838 participants (2,683 females and 2,155 males) included individuals aged >30 years who were undergoing a health examination from 2006 to 2014 in Pingzhen City, Taiwan. In the initial generalized estimated equation model analysis, which included the covariates of age of first visit, period between the first and current visit, and metabolic syndrome severity Z-score, the results indicated that the interaction between age and metabolic syndrome severity Z-score is significantly related to the estimated glomerular filtration rate for males ( p = .040). For females, the interaction between age and metabolic syndrome severity Z-score was not significant, but a higher metabolic syndrome severity Z-score was significantly associated with lower estimated glomerular filtration rate ( p = .001). After controlling for the confounders, unhealthy behaviors, and comorbidities, the metabolic syndrome severity Z-score was still a negative predictor of estimated glomerular filtration rate in both the male ( p = .005) and female ( p = .023) models.

scholarly journals Association of Thyroid Function With the Estimated Glomerular Filtration Rate in a Large Chinese Euthyroid Population

2018 ◽  
Vol 43 (4) ◽  
pp. 1075-1083 ◽  
Author(s):  
Kunlin Wang ◽  
Kaipeng Xie ◽  
Liubao Gu ◽  
Bo Xu ◽  
Jihai Chen ◽  
...  
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Thyroid Function ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate

Impact of Thyroid Function on Serum Cystatin C and Estimated Glomerular Filtration Rate: A Cross-Sectional Study

2013 ◽  
Vol 19 (3) ◽  
pp. 397-403 ◽  
Author(s):  
Yicong Ye ◽  
Xiaorong Gai ◽  
Hongzhi Xie ◽  
Li Jiao ◽  
Shuyang Zhang
Keyword(s):  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Thyroid Function ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Serum Cystatin C ◽  
Cross Sectional ◽  
Serum Cystatin

scholarly journals Physical Activity Is not Associated with Estimated Glomerular Filtration Rate among Young and Middle-Aged Adults: Results from the Population-Based Longitudinal Doetinchem Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (10) ◽  
pp. e0133864 ◽  
Author(s):  
Gerrie-Cor M. Herber-Gast ◽  
Gerben Hulsegge ◽  
Linda Hartman ◽  
W. M. Monique Verschuren ◽  
Coen D. A. Stehouwer ◽  
...  
Keyword(s):  
Physical Activity ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Filtration Rate ◽  
Estimated Glomerular Filtration Rate ◽  
Population Based ◽  
Middle Aged ◽  
Middle Aged Adults

scholarly journals Associations of blood biomarkers with glomerular filtration rate in patients with TIA and stroke: population-based study

2020 ◽  
pp. svn-2020-000422
Author(s):  
Dearbhla M. Kelly ◽  
Linxin Li ◽  
Annette I Burgess ◽  
Deborah L Poole ◽  
Julia M Duerden ◽  
...  
Keyword(s):  
Risk Factors ◽  
Glomerular Filtration Rate ◽  
Glomerular Filtration ◽  
Chronic Inflammation ◽  
Filtration Rate ◽  
Population Based ◽  
Tumour Necrosis Factor Receptor ◽  
Blood Biomarkers ◽  
Population Based Study ◽  
Fatty Acid Binding

Background and purposeNon-traditional risk factors such as chronic inflammation, oxidative stress and thrombogenic factors are believed to contribute to the excess stroke risk in chronic kidney disease (CKD) by triggering vascular injury and endothelial dysfunction. We aimed to determine how well a panel of biomarkers representative of these factors would correlate with estimated glomerular filtration rate (eGFR) in patients with recent transient ischaemic attack (TIA) or stroke. We also investigated whether eGFR would confound previously reported associations between biomarkers and mortality.MethodsWe studied a panel of 16 blood biomarkers related to inflammation, thrombosis, atherogenesis and cardiac or neuronal cell damage in TIA or ischaemic stroke in a population-based study (Oxford Vascular Study). Biomarker levels were log-transformed and correlated with eGFR, adjusted for age. Cox proportional hazard models were used for survival analysis.ResultsAmong 1297 patients with TIA or stroke, 52.7% (n=684) of patients had CKD (eGFR <60 mL/min/1.73 m2). There was a moderate correlation between log-eGFR and the log-transformed soluble tumour necrosis factor receptor-1 (R2=0.21), attenuating with adjustment for age (R2=0.12). There were moderate-to-strong correlations with markers of cardiac injury, N-terminal pro-brain natriuretic peptide and heart-type fatty acid binding protein (hFABP, R2=0.14 and 0.34, respectively). The strongest correlation after adjustment for age was between hFABP and eGFR (R2=0.20). Adjusting for eGFR did not impact any biomarker associations with mortality.ConclusionsCorrelations between biomarkers related to inflammation and thrombosis with renal dysfunction in the setting of cerebrovascular events were generally modest after adjustment for age, suggesting that putative risk factors such as chronic inflammation or coagulopathy are unlikely to be important stroke mechanisms in patients with CKD.

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