scholarly journals Barrett’s esophagus and esophageal cancer: Links to microbes and the microbiome

2018 ◽  
Vol 14 (12) ◽  
pp. e1007384 ◽  
Author(s):  
Teminioluwa A. Ajayi ◽  
Sarah Cantrell ◽  
Ashley Spann ◽  
Katherine S. Garman
2018 ◽  
pp. 39-50
Author(s):  
Jean Marc Chevallier ◽  
Sonja Chiappetta ◽  
Mario Musella

2013 ◽  
Vol 58 (11) ◽  
pp. 3178-3188 ◽  
Author(s):  
Katherine S. Garman ◽  
Kouros Owzar ◽  
Elizabeth R. Hauser ◽  
Kristen Westfall ◽  
Blair R. Anderson ◽  
...  

ASVIDE ◽  
2017 ◽  
Vol 4 ◽  
pp. 339-339
Author(s):  
Shilpa Jain ◽  
Sadhna Dhingra

2007 ◽  
Vol 120 (9) ◽  
pp. 1914-1921 ◽  
Author(s):  
Danielle M. Greenawalt ◽  
Cuong Duong ◽  
Gordon K. Smyth ◽  
Marianne L. Ciavarella ◽  
Natalie J. Thompson ◽  
...  

2008 ◽  
Vol 53 (11) ◽  
pp. 2858-2867 ◽  
Author(s):  
Tomoharu Miyashita ◽  
Furhawn A. Shah ◽  
Guy P. Marti ◽  
Todd D. Armstrong ◽  
Jiaai Wang ◽  
...  

2018 ◽  
Vol 90 (3) ◽  
pp. 19-24 ◽  
Author(s):  
Zbigniew Kula ◽  
Andrzej Nowicki ◽  
Alicja Świerszczyńska

Objective: The aim of the study was to evaluate the prevalence and clinical aspects of Barrett's esophagus and adenocarcinoma of the lower part of esophagus in gastroscopy. Material and methods: Retrospective review of 10000 upper gastrointestinal endoscopic examinations were performed at the Department of Oncology Endoscopy in Bydgoszcz from 2004 to 2014 in terms of incidence of Barrett's esophagus and adenocarcinoma in the lower part of esophagus. Results: The medical records of 5378 (53.8%) women and 4622 (46.2%) men were analyzed. The average age of men and women was 62.4 and 62.7, respectively. Barrett's esophagus was diagnosed in 67 patients, including 38 (56.7%) of men where the average age of men and women was 56.9 and 60.2 years, respectively. The most commonly reported symptom was heartburn occurred in 45 (67.2%) of patients. During ten years of follow-up PB examination the adenocarcinomas were detected in 3 (4.47%) cases. Adenocarcinoma was diagnosed in 46 patients, of whom 37 in men. In the case of 27 patients (58.7%), esophageal cancer was treated with the intention of radicalization. The probability of 5-year survival in these patients was 10.2% for women and 9.2% for men. Conclusions: The number of Barrett's esophagus and adenocarcinoma are increasing at 0.67% and 0.46% annually, respectively. The risk of adenocarcinoma developed from Barrett's esophagus during endoscopic follow-up period was 4.47%. Barrett's esophagus is more common in men before the age of 60, and nearly half of them have intestinal metaplasia without dysplasia. Probability of 5-year survival in patients with adenocarcinoma was 9.7%.


2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 152-152
Author(s):  
C. Lin ◽  
D. Kerstetter ◽  
F. Habr

152 Background: Up to 60% of patients with esophageal cancer are deemed inoperable at the time of diagnosis due to either advanced stage or significant co-morbidities. Currently, endoscopic palliative measures include stenting and photodynamic therapy. Although spray cryotherapy has been successfully used in ablating Barrett's esophagus, and different grades of dysplasia, there has been only one published case describing complete remission of squamous cell carcinoma following cryoablation. We present the first case of the use of the CryoSpray Ablation System (CSA Medical, Baltimore, MD) for palliative treatment of an esophageal T3 adenocarcinoma in an elderly woman with dysphagia and weight loss. Methods: An upper endoscopy was performed with standard monitored anesthesia. A special dual lumen Cryo decompression tube is introduced over an endoscopically placed savary guidewire in the gastric antrum and connected to suction. This tube is used to decompress the stomach when the liquid nitrogen is sprayed. Cryoablation is performed using the CryoSpray Ablation System that uses liquid nitrogen is delivered via a 7 Fr catheter at low pressures (2-3 PSI) at -196°C.The lesion was treated with four freeze cycles of 10-20 seconds each with 60 second interim thaws. Freezing and thawing techniques were monitored by direct visualization. The procedure is repeated every 4-6 weeks. The patient received a total of 7 treatments over 10 months. Results: The patient did not experience any adverse effects after treatment. After 3 treatments (week 20), complete endoscopic resolution of the lesion was noted, with regression of the Barrett's mucosa and major improvement of her dysphagia. At week 28, a recurrent mass was seen on EGD in the mid-esophagus. This was treated with 3 sessions of spray cryotherapy at 4 week intervals with improvement of dysphagia after each application. 11 months after her initial cryotherapy, the patient opted to have an esophageal stent due to tumor progression. Conclusions: Spray cryotherapy is a safe and effective endoscopic modality for the ablation of Barrett's esophagus and superficial esophageal cancer, it is a promising new modality for the palliation of advanced esophageal cancer. No significant financial relationships to disclose.


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