An Analysis of the Factors Limiting Maximal Oxygen Consumption in Healthy Subjects

CHEST Journal ◽  
1992 ◽  
Vol 101 (5) ◽  
pp. 188S-191S ◽  
Author(s):  
Pietro Enrico di Prampero
Keyword(s):  
Oxygen Consumption ◽  
Healthy Subjects ◽  
Maximal Oxygen Consumption

Training-induced changes in hormonal and metabolic responses to submaximal exercise

1979 ◽  
Vol 46 (4) ◽  
pp. 766-771 ◽  
Author(s):  
W. W. Winder ◽  
R. C. Hickson ◽  
J. M. Hagberg ◽  
A. A. Ehsani ◽  
J. A. McLane
Keyword(s):  
Oxygen Consumption ◽  
Healthy Subjects ◽  
Maximal Oxygen Consumption ◽  
Bicycle Ergometer ◽  
Submaximal Exercise ◽  
Metabolic Responses ◽  
Plasma Glucagon ◽  
Induced Changes ◽  
Ergometer Test ◽  
Bicycle Ergometer Test

Plasma glucagon and catecholamines increase during prolonged submaximal exercise, but the magnitude of the increase is less in endurance-trained individuals than in untrained subjects. We have studied the rapidity at which this adaptation occurs. Six initially untrained healthy subjects exercised vigorously (on bicycle ergometers and by running) 30–50 min/day, 6 days/wk, for 9 wk. Prior to the beginning of training and at 3-wk intervals thereafter, participants were subjected to 90-min bicycle ergometer test work loads that elicited 58 +/- 2% of the subjects' initial maximal oxygen consumption. The major proportion of the training-induced decrement in plasma glucagon and catecholamine responses to exercise was seen after 3 wk of training. We conclude that the hormonal component of the training adaptation occurs very early in the course of a vigorous endurance training program.

scholarly journals Acute Negative Effect Of The Surgical Type Facemask In The Maximal Oxygen Consumption In Healthy Subjects

2021 ◽  
Vol 53 (8S) ◽  
pp. 10-10
Author(s):  
David Garza-Saucedo ◽  
Dulce Edith Morales-Elizondo ◽  
Pedro G. Morales-Corral ◽  
Victor M. Salinas-Torres
Keyword(s):  
Oxygen Consumption ◽  
Healthy Subjects ◽  
Maximal Oxygen Consumption ◽  
Negative Effect

Nonlinear increases in diffusing capacity during exercise by seated and supine subjects

1981 ◽  
Vol 51 (4) ◽  
pp. 858-863 ◽  
Author(s):  
D. L. Stokes ◽  
N. R. MacIntyre ◽  
J. A. Nadel
Keyword(s):  
Carbon Monoxide ◽  
Oxygen Consumption ◽  
Healthy Subjects ◽  
Vital Capacity ◽  
Maximal Exercise ◽  
Sitting Position ◽  
Diffusing Capacity ◽  
Heavy Exercise ◽  
Lung Volumes ◽  
Rate Of Increase

To study the effects of exercise on pulmonary diffusing capacity, we measured the lungs' diffusing capacity for carbon monoxide (DLCO) during exhalation from 30 to 45% exhaled vital capacity in eight healthy subjects at rest and during exercise while both sitting and supine. We found that DLCO at these lung volumes in resting subjects was 26.3 +/- 3.2% (mean +/- SE) higher in the supine than in the sitting position (P less than 0.001). We also found that, in both positions, DLCO at these lung volumes increased significantly (P less than 0.001) with increasing exercise and approached similar values at maximal exercise. The pattern of increase in DLCO with an increase in oxygen consumption in both positions was curvilinear in that the rate of increase in DLCO during mild exercise was greater than the rate of increase in DLCO during heavy exercise (P = 0.02). Furthermore, in the supine position during exercise, it appeared that DLCO reached a physiological maximum.

β-Adrenergic receptor number in human lymphocytes is inversely correlated with aerobic capacity

1998 ◽  
Vol 274 (6) ◽  
pp. E1106-E1112 ◽  
Author(s):  
Nobuharu Fujii ◽  
Sachiko Homma ◽  
Fumio Yamazaki ◽  
Ryoko Sone ◽  
Takeshi Shibata ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Aerobic Capacity ◽  
Adrenergic Receptor ◽  
Ventilatory Threshold ◽  
Human Lymphocytes ◽  
Mrna Level ◽  
Maximal Oxygen Consumption ◽  
Subsequent Degradation ◽  
Intracellular Compartments ◽  
Model Cell

In the present study, the relationships between β-adrenergic receptor (β-AR) expression and aerobic capacity evaluated by maximal oxygen consumption ([Formula: see text]) and oxygen consumption level at ventilatory threshold (V˙o 2@VT) were investigated. Seventeen physically untrained and 25 trained men participated in the study. After supine resting, the peripheral blood was sampled for preparation of lymphocytes, the model cell used to analyze the β-AR state. The total number of β-AR in lymphocytes (β-ARtotal) was inversely correlated with theV˙o 2 max( r = −0.368; P < 0.05) and theV˙o 2@VT ( r = −0.359; P < 0.05). Similar relationships were also observed between the number of β-AR in cell surface and both V˙o 2 max( r = −0.491; P < 0.05) andV˙o 2@VT ( r = −0.498; P < 0.05). However, no correlation was obtained between the number of β-AR in intracellular compartments and eitherV˙o 2 max orV˙o 2@VT. The β2-AR mRNA level quantified by the use of competitive reverse transcription-polymerase chain reaction was inversely correlated withV˙o 2@VT ( r = −0.567; P < 0.05) and positively correlated with β-ARtotal( r = 0.521; P < 0.05). These findings suggest that the β-AR number in lymphocytes is inversely correlated with aerobic capacity. This relationship may be explained by downregulation of β-AR, including internalization with subsequent degradation of the receptors and inhibition of the β-AR biosynthesis.

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