Secretion of Inhibin A and Inhibin B During Pregnancy and Early Postpartum Period in Japanese Monkeys

Plasma concentrations of inhibin A and inhibin B during pregnancy and early lactation in chimpanzees were determined by enzyme-linked immunosorbent assay (ELISA). Plasma samples were taken from five pregnant chimpanzees at 6-9, 10, 20 and 25 weeks of pregnancy, and following parturition. Throughout pregnancy and the early postpartum period, circulating inhibin A and inhibin B concentrations remained low, at similar levels to those during the normal menstrual cycle in chimpanzees. Concentrations of inhibin A in the placental homogenate were high enough to be measured by the ELISA and by bioassay, whereas circulating inhibin bioactivities in late pregnancy were too low to be measured. Plasma concentrations of FSH remained low with no significant changes throughout pregnancy and the postpartum period. Plasma concentrations of oestradiol-17beta and progesterone at 25 weeks of pregnancy were much higher than normal menstrual cycle levels. It was concluded that in chimpanzees the levels of circulating inhibin A and inhibin B remained low throughout pregnancy and the early postpartum period, and that the concentrations of bioactive dimeric inhibin did not increase towards the end of pregnancy. The suppression of circulating FSH levels during pregnancy is suggested to be controlled by steroid hormones that increased significantly in late pregnancy, and the present findings further suggest that the secretory pattern and role of inhibin during pregnancy in chimpanzees may be different from that in human and other primates.

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Secretion of Leptin Throughout Pregnancy and Early Postpartum Period in Japanese Monkeys: Placenta as Another Potential Source of Leptin

Endocrine ◽

10.1385/endo:27:1:075 ◽

2005 ◽

Vol 27 (1) ◽

pp. 075-082 ◽

Cited By ~ 10

Author(s):

Cheng Wang ◽

Mohamed S. Medan ◽

Keiko Shimizu ◽

Chihiro Kojima ◽

Mariko Itoh ◽

...

Keyword(s):

Postpartum Period ◽

Early Postpartum Period ◽

Japanese Monkeys ◽

Potential Source ◽

Early Postpartum

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Paracetamol/acetaminophen (single administration) for perineal pain in the early postpartum period

Cochrane Database of Systematic Reviews ◽

10.1002/14651858.cd008407.pub3 ◽

2021 ◽

Author(s):

Edgardo Abalos ◽

Yanina Sguassero ◽

Gillian ML Gyte

Keyword(s):

Postpartum Period ◽

Perineal Pain ◽

Single Administration ◽

Early Postpartum Period ◽

Early Postpartum

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Exclusive Breastfeeding Is Not Associated with Maternal–Infant Bonding in Early Postpartum, Considering Depression, Anxiety, and Parity

Nutrients ◽

10.3390/nu13041184 ◽

2021 ◽

Vol 13 (4) ◽

pp. 1184

Author(s):

Naoki Fukui ◽

Takaharu Motegi ◽

Yuichiro Watanabe ◽

Koyo Hashijiri ◽

Ryusuke Tsuboya ◽

...

Keyword(s):

Mental Health ◽

Path Analysis ◽

Exclusive Breastfeeding ◽

Postpartum Period ◽

Depression Scale ◽

Anxiety And Depression ◽

Women’S Mental Health ◽

Women's Mental Health ◽

Early Postpartum Period ◽

Early Postpartum

It is important to clarify how the breastfeeding method affects women’s mental health, and how women’s mental health affects the breastfeeding method in the early postpartum period when major depression and other psychiatric problems are most likely to occur. This study aimed to examine this bidirectional relationship in the early postpartum period. Participants were 2020 postpartum women who completed the Hospital Anxiety and Depression Scale (HADS) and Mother-to-Infant Bonding Scale (MIBS). We obtained data for participants’ breastfeeding method for four weeks after childbirth. We performed a path analysis with factors including breastfeeding method (exclusive breastfeeding or non-exclusive breastfeeding), parity (primipara or multipara), the two HADS subscales (anxiety and depression), and the two MIBS subscales (lack of affection and anger and rejection). The path analysis showed that breastfeeding method did not significantly affect depression, anxiety, and maternal–infant bonding in the early postpartum period. Women with higher anxiety tended to use both formula-feeding and breastfeeding. Our study suggests that exclusive breastfeeding is not associated with maternal-fetal bonding in early postpartum, considering depression, anxiety, and parity.

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