scholarly journals Opportunistic parasitic infections in patients with human immunodeficiency virus/acquired immunodeficiency syndrome: A review

2020 ◽  
Vol 13 (4) ◽  
pp. 716-725 ◽  
Author(s):  
D. A. Laksemi ◽  
L. T. Suwanti ◽  
M. Mufasirin ◽  
K. Suastika ◽  
M. Sudarmaja

The number of human immunodeficiency virus (HIV) cases increases annually, and Indonesia has become the country with the fastest HIV/acquired immunodeficiency syndrome (AIDS) epidemic spread among the five Southeast Asian countries. Indonesia entered the critical phase of HIV/AIDS infections after 5 out of the 33 provinces, namely, Papua, Jakarta, Bali, West Java, and East Java, reported HIV/AIDS epidemic since 2004. In AIDS pathophysiology and immune-suppression are severe, thus, opportunistic intestinal parasitic infections that cause diarrhea in HIV infection may be fatal. Several studies have suggested that Cryptosporidium parvum, Isospora belli, and Blastocystis hominis are the most common intestinal protozoan parasites categorized as AIDS associated illness. Diarrhea caused by parasites is considerably suspected in the cases of chronic and persistent diarrhea in adults, in an era of increasing HIV/AIDS cases nowadays. The present review highlights the current advances in etiologic agents of HIV/AIDS opportunistic infections among countries, epidemiology and prevalence, lifecycle, risk factors, examination methods, and treatment.

e-CliniC ◽  
2014 ◽  
Vol 2 (1) ◽  
Author(s):  
Christy B Tumbelaka

Abstract: Human Immunodeficiency Virus (HIV) is virus that causes Acquired Immunodeficiency Syndrome (AIDS), which is a retrovirus disease that characterized by the severe immunosuppression that cause opportunistic infection, secondary neoplasm and neurologic manifestations. Nervous system involvement in HIV infections may occur directly through the virus and indirectly as a result of opportunistic infections due to immunocompromised. This study aimed to determine the incidence of intracranial complication in HIV/AIDS patients who were hospitalized in Neurology Ward of RSUP Prof. Dr. R. D. Kandou Manado from July 2012 to June 2013. This study were a retrospective descriptive study using medical record of patients with HIV/AIDS. The results showed there were 36 patients with HIV/AIDS and 27 patients had intracranial complications. Tuberculous Meningitis was the most common type of complications with percentage (51,9%). Based on those 27 HIV/AIDS patients with intracranial complication, patients who were 25-34 years old (44%) have the most intracranial complication. Based on the gender percentage, it is dominated by male (59,3%) and based on the occupations, it is commonly came from entrepreneurs (29,6%). Conclusion: The incidences of intracranial complication in patients with HIV/AIDS were quite high on Tuberculous Meningitis, and it is dominated by male. The highest distributions were found on aged 25-34 whose occupation were entrepreneurs. Keywords: Intracranial Complication, HIV/AIDS, patients.   Abstrak: Human Immunodeficiency Virus (HIV) merupakan virus yang menyebabkan penyakit Acquired Immunodeficiency Syndrome (AIDS) yaitu suatu penyakit retrovirus yang ditandai dengan imunosupresi berat yang menimbulkan infeksi oportunistik, neoplasma sekunder, dan manifestasi neurologis. Keterlibatan sistem saraf pada infeksi HIV dapat terjadi secara langsung karena virus tersebut dan tidak langsung akibat infeksi oportunistik akibat imunokompromis. Penelitian ini bertujuan untuk mengetahui angka kejadian komplikasi intrakranial pada penderita HIV/AIDS yang di rawat inap di Bagian Neurologi RSUP Prof. Dr. R. D. Kandou Manado selama periode Juli 2012 – Juni 2013. Metode penelitian ini ialah deskriptif retrospektif dengan menggunakan catatan rekam medik penderita HIV/AIDS. Hasil peneitian memperlihatkan dari 36 pasien HIV/AIDS, terdapat 27 penderita yang memiliki komplikasi intrakranial dengan persentase jenis komplikasi intrakranial terbanyak yaitu Meningitis Tuberkulosis (51,9%). Dari 27 penderita HIV/AIDS yang memiliki komplikasi intrakranial paling banyak ialah pada kelompok umur 25-34 tahun (44,4%) sedangkan untuk jenis kelamin, didominasi oleh penderita berjenis kelamin laki-laki (59,3%), dan jenis pekerjaan terbanyak ialah wiraswasta (29,6%). Kesimpulan: Angka kejadian komplikasi intrakranial pada penderita HIV/AIDS yang cukup tinggi terdapat pada Meningitis Tuberkulosis dengan jenis kelamin terbanyak ialah laki-laki. Distribusi yang cukup tinggi pula ditemukan pada kelompok umur 25-34 tahun dengan jenis pekerjaan sebagai wiraswasta. Kata Kunci: Komplikasi Intrakranial, HIV/AIDS, penderita


2021 ◽  
Vol 10 (2) ◽  
pp. 83-86
Author(s):  
Sanjeet Bhattarai ◽  
Devendra Shah ◽  
Sulav Rayamajhi ◽  
Yuvaraj Bhusal ◽  
Kishor Khanal ◽  
...  

Currently, there is no cure for Human immunodeficiency virus /Acquired immunodeficiency syndrome (HIV/AIDS) but, there are medications to control HIV and prevent opportunistic infections. Clinicians must be vigilant enough to extract history and send relevant laboratory investigations to diagnose the disease in early stage. Patient may not have known his /her diagnosis or intentionally avoided to reveal the disease status which further complicates the diagnosis and treatment. This is case of a 51 years male, where social stigma forces the patient to hide his diagnosis and reluctant to seek medical treatment ultimately reaps the life. Hence, government and concerned authority must work up for wide availability of HIV/AIDS medications and motivate people to seek medical advices as soon as possible. Concerned authority must motivate people to consider it as any other treatable disease.


2021 ◽  
Vol 10 (16) ◽  
pp. e561101624159
Author(s):  
Edvaldo Benevides de Souza ◽  
Renata Campos Silva ◽  
Nádia Cristina Ferraz Chiachio

A síndrome da imunodeficiência adquirida (SIDA; AIDS - acquired immunodeficiency syndrome) é uma manifestação clínica avançada, decorrente de um quadro de imunodeficiência causado pelo vírus da imunodeficiência humana (VIH, HIV-human immunodeficiency virus), o qual é transmitido pelas vias sexual, parenteral ou vertical. (UNAIDS. AIDS epidemic update; 2007). O HIV altera o DNA da célula, cria um ciclo de infecção em que, continuamente se multiplica, o que a tornou uma patologia crônica e potencialmente letal (Brasil, 2020). Para conter o quadro epidêmico da doença, faz-se estritamente necessário o acompanhamento e tratamento dos pacientes infectados. Diante disso, foi realizado a partir deste artigo, um estudo transversal descritivo, com base em dados do SINAN (Sistema de Informação de Agravos de Notificação), disponíveis no DATASUS, entre os períodos de 2010 e 2020, em cujo objetivo foi verificar o perfil epidemiológico das pessoas que vivem com HIV-AIDS, no Município de Vitória da Conquista, e constatar os efeitos da estigmatização da doença, do preconceito e mais atualmente da pandemia causada pelo vírus Covid-19. Dos dados coletados, cerca de 59,81% dos pacientes eram do sexo masculino, e 56,12% do sexo feminino. A maioria dos casos diagnosticados eram jovens de 18 a 28 anos. Em relação às notificações, as mesmas se mantiveram instáveis até o ano de 2019, no total em cerca de 24.000 a 25.000 casos notificados. Já no ano de 2020, ocorreu uma queda, com 8.434 casos notificados. Quanto à questão das raças, na pesquisa apontam para um aumento no número de casos de aids entre os pretos e pardos para ambos os sexos; negros foram cerca de 3.000 em 2008, passando por 1.915 em 2019, decaindo para 541 casos. Já os pardos, em cerca de 9.000 mil, em 2008, decaindo para 2.474, em 2020, enquanto que entre os brancos apontam para uma redução proporcional. Portanto, o estudo conclui que, questões sociais e outros fatores externos refletem no perfil de pacientes infectados pelo vírus HIV, assim como provocam alterações nos índices da doença no município de Vitória da Conquista.


2017 ◽  
Vol 5 (2) ◽  
pp. 1-12
Author(s):  
Nur Syamsi NL

AIDS (Acquired Immunodeficiency Syndrome) adalah syndrom yang timbul akibat adanya virus HIV (Human Immunodeficiency Virus) yang menyerang sistem kekebalan tubuh manusia. HIV/AIDS dapat menular melalui darah, sperma, cairan vagina, dan ASI (Air Susu Ibu). Penelitian ini dilakukan di Akademi Kebidanan Sandi Karsa Makassar yang terletak di jalan Bung lorong 2, Kelurahan Tamalanrea, Kecamatan Tamalanrea Jaya, Makassar. Jenis penelitian yang digunakan dalam penelitian ini bersifat deskriptif. Besarnya sampel yang digunakan adalah 30 responden dari 600 populasi yang dipilih secara Total Sampling. Di mana dalam pengambilan data digunakan instrumen berupa kuesioner yang dibagikan kepada responden. Dari keseluruhan responden didapatkan tingkat pengetahuan mahasiswa Akademi Kebidanan Sandi Karsa Makassar yang diteliti didapat 15 mahasiswa (50%) yang tingkat pengetahuan baik tentang HIV/AIDS dan terdapat 14 mahasiswa (46,7%) yang tingkat pengetahuan cukup tentang HIV/AID dan terdapat 1 mahasiswa (3,3%) yang tingkat pengetahuan kurang tentang HIV/AIDS


2021 ◽  
Vol 2 (1) ◽  
pp. 55-63
Author(s):  
Machria Rachman

HIV (Human Immunodeficiency Virus)  dan AIDS (Acquired Immunodeficiency Syndrome masih menjadi ancaman kesehatan masyarakat secara global. Prevalensi HIV/AIDS di Kabupaten Banyuwangi juga cukup tinggi yakni 4.557 kasus. Cara penularan HIV terbesar adalah melalui hubungan seksual (71 %). Sejumlah 18,23% orang dengan HIV/AIDS (ODHA) adalah wanita pekerja seks (WPS). Meskipun lokalisasi di Banyuwangi telah resmi ditutup pada tahun 2013, namun praktik prostitusi masih terselubung dijalankan. Hubungan seksual tanpa kondom menjadi mata rantai penyebaran HIV/AIDS di masyarakat. Tujuan penelitian ini adalah untuk mengetahui korelasi pengetahuan dan sikap WPS dengan persuasi penggunaan kondom di eks lokalisasi Gempol Porong Kabupaten Banyuwangi. Desain penelitian adalah analitik kuantitatif dengan menggunakan pendekatan cross sectional. Sampel penelitian yaitu WPS di Eks Lokalisasi Gempol Porong berjumlah 32 orang yang diambil dengan teknik Total sampling. Pengambilan data dengan metode angket dan dianalisis statistik menggunakan SPSS 20.0 version. Hasil penelitian menunjukkan bahwa WPS yang memiliki pengetahuan rendah dalam penanggulangan HIV/AIDS sebanyak 56,2 %, sikap negatif sebesar 53,1% dan sebanyak 59,4% tidak melakukan persuasi penggunaan kondom. Analisis uji chi-Square menunjukkan ada hubungan antara pengetahuan WPS dalam penanggulangan HIV/AIDS dengan persuasi penggunaan kondom (ρ = 0,002α), serta ada hubungan antara sikap WPS dalam upaya penanggulangan HIV/AIDS dengan persuasi penggunaan kondom (nilai ρ = 0,000α). Variabel yang berpengaruh terhadap penanggulangan HIV/AIDS dengan persuasi penggunaan kondom adalah sikap, dengan  probabilitas sikap negatif WPS sebesar 78%. Penelitian ini diharapkan dapat memberikan masukan pihak terkait guna peningkatan 100% penggunaan kondom sehingga dapat menekan angka pertumbuhan HIV/AIDS di Kabupaten Banyuwangi.


2018 ◽  
Vol 32 (5) ◽  
pp. 534-545 ◽  
Author(s):  
Erik W. Skoglund ◽  
Kierra M. Dotson ◽  
Casey J. Dempsey ◽  
Christy P. Su ◽  
Farnaz Foolad ◽  
...  

Purpose: The most significant peer-reviewed articles pertaining to infectious diseases (ID) pharmacotherapy, as selected by panels of ID pharmacists, are summarized. Summary: Members of the Houston Infectious Diseases Network (HIDN) were asked to nominate peer-reviewed articles that they believed most contributed to the practice of ID pharmacotherapy in 2017, including the areas of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). A list of 33 articles related to general ID pharmacotherapy and 4 articles related to HIV/AIDS was compiled. A survey was distributed to members of the Society of Infectious Diseases Pharmacists (SIDP) for the purpose of selecting 10 articles believed to have made the most significant impact on general ID pharmacotherapy and the single significant publication related to HIV/AIDS. Of 524 SIDP members who responded, 221 (42%) and 95 (18%) members voted for general pharmacotherapy- and HIV/AIDS-related articles, respectively. The highest ranked articles are summarized below. Conclusion: Remaining informed on the most significant ID-related publications is a challenge when considering the large number of ID-related articles published annually. This review of significant publications in 2017 may aid in that effort.


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