Effects of Anti-inflammatory Diet in the Context of Lifestyle Modification (with or without Metformin Use) on Metabolic, Endocrine, Inflammatory and Reproductive Profiles in Overweight and Obese Women with Polycystic Ovary Syndrome: Controlled Clinical Trial

Author(s):  
Amany A. Salama ◽  
2009 ◽  
Vol 94 (2) ◽  
pp. 469-476 ◽  
Author(s):  
Vanita R. Aroda ◽  
Theodore P. Ciaraldi ◽  
Paivi Burke ◽  
Sunder Mudaliar ◽  
Paul Clopton ◽  
...  

2016 ◽  
Vol 11 (4) ◽  
pp. 337-341
Author(s):  
Adrian NEACȘU ◽  
◽  
Cătălina Diana STĂNICĂ ◽  
Constantin Dimitrie NANU ◽  
◽  
...  

Polycystic ovary syndrome (PCOS) is a common endocrine and heterogeneous dysfunction, characterized by chronic anovulation and androgen excess, affecting 6-10% of women of childbearing age. It is the most common cause of anovulatory infertility. It seems that the key element in the pathophysiology of PCOS is increased insulin resistance. The correction of infertility in teens is not a priority. They can receive treatment to normalize menstrual cycles, with the reduction of symptoms and improvement of metabolic disorders. Many overweight teens have increased insulinemia, which may play a role in the development of PCOS. Standard treatment is oral estroprogestative, used to perform regular menstrual cycles. Normalize menstrual cycles can be done with oral contraceptives or oral antidiabetic agents that improve metabolic dysfunctions. An adjuvant approach of the utmost importance for teens is lifestyle modification and diet. Teen treatment should be individualized depending on a number of peculiarities that have to be taken into account: menstruation disorders, mastopathies and ovarian dystrophies, hyperandrogenism syndrome, sexually transmitted diseases and other associated disorders. In obese women with PCOS, weight loss improves hyperandrogenism, reduces metabolic disturbances, reduces insulin resistance and insulinemia, improves fertility rate, stimulates ovulation.


Cytokine ◽  
2019 ◽  
Vol 120 ◽  
pp. 66-70 ◽  
Author(s):  
Wagner Silva Dantas ◽  
Willian das Neves ◽  
Saulo Gil ◽  
Cristiano Roberto Grimaldi Barcellos ◽  
Michele Patrocínio Rocha ◽  
...  

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