scholarly journals Synthesis and Antibacterial Activity of Novel Molybdenum Complexes with Macrocyclic Schiff Base Derived from Furanylethanedione

2019 ◽  
Vol 31 (11) ◽  
pp. 2607-2612
Author(s):  
Ramesh Kumar Gautam ◽  
Chandra Prakash Singh ◽  
Shiv Govind Prasad ◽  
Rajul Saxena ◽  
Devendra Pratap Rao
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Thermal Studies ◽  
Molar Conductance ◽  
Moderate Activity ◽  
Octahedral Structure ◽  
Molybdenum Metal ◽  
Distorted Octahedral ◽  
Elemental Analyses ◽  
Macrocyclic Schiff Base

A new MoO2(VI) complex of formulation [MoO2(L)](acac)2 prepared by a Schiff base, synthesized via reaction of di-2-furanylethanedione with 5-chloropyridine-2,3-diamine and four new MoO2(VI) complexes having formule [MoO2(ML)](acac)2, derived from cyclization of [MoO2(L)](acac)2 with β-diketones are reported in this work. The synthesized MoO2(VI) complexes were characterized on the basis of various analyses like thermal studies, UV-Vis, elemental analyses, NMR, IR and molar conductance. The coordination number of molybdenum metal is six. All the MoO2(VI) complexes have distorted octahedral structure in which Mo atom is coordinated with two O-atoms and four N-atoms. All the complexes show moderate activity against S. typhi and S. aureus. Advancement in the antibacterial task is thought to be of chelation speculation.

scholarly journals Cis-Dioxomolybdenum (VI) Complexes with N-donor Macrocyclic Ligands

2021 ◽  
Vol 12 (1) ◽  
pp. 1352-1364
Keyword(s):  
Schiff Base ◽  
Coordination Number ◽  
Thermal Studies ◽  
Molar Conductance ◽  
Macrocyclic Ligands ◽  
Molybdenum Metal ◽  
Distorted Octahedral ◽  
Elemental Analyses

The preparation of one monomeric [MoO2(L)](acac)2 having a Schiff base came by condensation of di-2-furanylethanedione with 2,3-diaminotoluene and 4 different complexes having formulation [MoO2(ML)](acac)2, from the result of [MoO2(L)](acac)2 with 1,3-diketones will be described with this paper. The preparation of each of these five MoO2 (VI) complexes was symbolized by thermal studies, UV-Vis, IR, elemental analyses, NMR, and molar conductance. The coordination number of molybdenum metal will be six. All 5 complexes of MoO2(VI) have a geometry of distorted octahedral arrangement. The octahedral arrangement of Mo-metal in prepared complexes is finished by 2 oxo O-atoms and 4 N-atoms from the synthesized ligand. All of the synthesized complexes demonstrated moderate action against S. aureus and S. typhi. The progression inside the antibacterial task being defined on the thought of chelation speculation.

scholarly journals Synthesis, Spectral Characterization and Antibacterial Investigation of Ni(II) Coordination Complexes of Macrocyclic Schiff base ligands Derived from 4-Aminoantipyrine

2017 ◽  
Vol 13 (1) ◽  
pp. 5948-5958
Author(s):  
Abraham Lincoln ◽  
Srinath Boinapalli ◽  
A. Anil Kumar
Keyword(s):  
Antibacterial Activity ◽  
Spectral Analysis ◽  
Schiff Base ◽  
Schiff Bases ◽  
Thermal Studies ◽  
Coordination Complexes ◽  
Molar Conductance ◽  
Schiff Base Ligands ◽  
Macrocyclic Schiff Base ◽  
Donor System

A series of Ni(II) complexes (NiL1-NiL5) have been synthesized from macrocyclic Schiff base ligands (L1-L5) were obtained from condensation of  4-aminoantipyrine derivative (L) with different diamines and hydrazides. All these compounds were well characterized by elemental, spectral analysis(mass, IR, 1H-NMR, electronic), magnetic suseceptibility, molar conductance and thermal studies. Macrocyclic Schiff bases are tetradentate with N4 donor system around the metal ion.Octahedral geometry have been assigned for all complexes. All ligands and complexes were examined for antibacterial activity and found that complexes were more potent when compared to ligands.  

scholarly journals Studies on Coordination Chemistry and Antibacterial Activity of Bidentate NS Schiff Base Derived From SBDTC and 4-Benzyloxybenzaldehyde

2019 ◽  
Vol 11 (1) ◽  
pp. 121-132 ◽  
Author(s):  
M. H. Islam ◽  
M. C. Sheikh ◽  
M. A. A. A A. Islam
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Metal Ions ◽  
Free Ligand ◽  
Molar Conductance ◽  
Absolute Ethanol ◽  
Moderate Activity ◽  
Spectroscopic Techniques ◽  
Biological Potential ◽  
Test Organisms

The condensation of 4-benzyloxybenzaldehyde with S-benzyl dithiocarbazate (SBDTC) in absolute ethanol afforded the Schiff base, S-benzyl-β-N-(4-benzyloxyphenyl)methylene-dithiocarbazate (1). The ligand on further reaction with metal ions in absolute ethanol [for Ni(II), Cu(II), Zn(II)] and in methanol [Pd(II)] resulted in the formation of the corresponding four coordinate complexes. The ligand and its complexes were characterized by physico-chemical techniques, viz., molar conductance, magnetic susceptibility measurement, IR, NMR and solution UV/Vis spectroscopic techniques. The complexes demonstrated stronger antibacterial activity than the free ligand indicating that coordination with these metal ions has enhanced biological potential of the ligand. All the compounds exhibited more or less moderate activity against the test organisms.

scholarly journals Ni (II), Cu (II) and Zn (II) Metal Chelates With Some Thiazole Derived Schiff-Bases: Their Synthesis, Characterization and Bactericidal Properties

1999 ◽  
Vol 6 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Zahid H. Chohan
Keyword(s):  
Escherichia Coli ◽  
Antibacterial Activity ◽  
Schiff Bases ◽  
Magnetic Moments ◽  
Metal Chelates ◽  
Conductivity Measurements ◽  
Octahedral Structure ◽  
Distorted Octahedral ◽  
Bactericidal Properties ◽  
Elemental Analyses

A number of thiazole derived tridentate Schiff-bases (LH) and its metal chelates of the type [M(L)2X] where M=Ni(II), Cu(II) and Zn(II), L=substituted salicylaldehyde (5-H, 5-CH3, 5-OCH3, 5-NO2 and 5-Cl) and X=CI have been synthesized and characterized with the help of elemental analyses, conductivity measurements, magnetic moments, UV-Vis, IR and NMR spectral data. An octahedral structure for Ni(II) and Zn(II) and a distorted octahedral structure for Cu(II) chelates have been proposed. All the Schiff-bases and their metal chelates have been screened for their biological activity against Escherichia coli, Staphylococcus aureous , Pseudomonas aeruginosa and Klebsiella pneumonae and in comparison, the metal chelates have been shown to possess more antibacterial activity than the uncomplexed Schiff-bases.

scholarly journals Cobalt (II) and Nickel (II) Complexes with Schiff Base Ligand Derived From 4-Amino Antipyrine: Synthesis, Spectral, Characterization and Thermal Studies

2018 ◽  
Vol 7 (4.37) ◽  
pp. 198
Author(s):  
Ahmed Razzaq Ibrahim Al-Faris ◽  
Wafaa Mahdi Sachit Alkoofee ◽  
. .
Keyword(s):  
Schiff Base ◽  
Melting Point ◽  
Metal Complexes ◽  
Schiff Base Ligand ◽  
Thermal Studies ◽  
Molar Conductance ◽  
Conductance Data ◽  
Elemental Analyses ◽  
Uv Visible ◽  
Chloride Salts

Metal complexes of the Schiff base ligand, synthesized via condensation p-dimethylamino benzaldehyde with Bis (4-aminoantipyrine) benzene 1, 4-diamine which has synthesized from condensation 1, 4-phenylene diamine and 4-aminoantipyrine, are synthesized from chloride salts of Co (II) and Ni(II) with ligand in ethanol. The metal complexes and ligand are characterized on the basis of elemental analyses, melting point, molar conductance, UV –Visible, FTIR and thermogravimetric analysis. The molar conductance data reveal that the metal chelates of the ligand with Co (II) and Ni (II) are electrolytes. The present results suggested that the Schiff base ligand as tetradentate is coordinated with metal ions through the four nitrogen atoms. 

scholarly journals Synthesis , Spectroscopic and Antibacterial Studies of Zinc(II) Complexes Derived from Salicylaldehyde, Leucylalanine and Glycylglycine

2012 ◽  
Vol 9 (3) ◽  
pp. 532-540 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Schiff Base ◽  
Bacterial Species ◽  
Conductivity Measurement ◽  
Growth Inhibitor ◽  
Molar Conductance ◽  
Diffusion Method ◽  
Schiff Base Ligands ◽  
Elemental Analyses ◽  
L1 And L2

Two Schiff base ligands L1 and L2 have been obtained by condensation of salicylaldehyde respectively with leucylalanine and glycylglycine then their complexes with Zn(II)were prepared and characterized by elemental analyses , conductivity measurement , IR and UV-Vis .The molar conductance measurement indicated that the Zn(II) complexes are 1:1 non-electrolytes. The IR data demonstrated that the tetradentate binding of the ligands L1 and L2 . The in vitro biological screening effect of the investigated compounds have been tested against the bacterial species Staphlococcus aureus, Escherichia coil , Klebsiella pneumaniae, Proteus vulgaris and Pseudomonas aeruginosa by the disc diffusion method . A comparative study of inhibition values of the Schiff base ligands and their complexes indicated that the complexes exhibit higher antimicrobial activity than the free ligands . Zinc ions are proven to be essential for the growth-inhibitor effect. The extent of inhibition appeared to be strongly dependent on the initial cell density and on the growth medium .

Synthesis and Characterization of Cr (III) Macrocyclic Schiff Base Complexes

2021 ◽  
pp. 269-274
Author(s):  
Dharmendra Kumar Sahu ◽  
Shekhar Srivastava
Keyword(s):  
Schiff Base ◽  
Molar Conductance ◽  
Photoelectron Spectra ◽  
Schiff Base Complexes ◽  
Squaric Acid ◽  
Schiff Base Ligands ◽  
X Ray ◽  
Trimesic Acid ◽  
Macrocyclic Schiff Base

Ninety Cr(III) macrocyclic Schiff base complexes of the type [CrL_n^(1-10) X_2 ]X(Where X = Cl- or NO-3 or CH3COO- and = macrocyclic Schiff base ligands derived from condensation of trimesic acid or p-phthalic acid or squaric acid with different aliphatic diamines) have been synthesised and characterised by elemental analysis; molar conductance; electronic spectra; IR; magnetic moment and XPS i.e. X-ray Photoelectron spectra data. An octahedral geometry was established for them.

Synthesis, complexation and antifungal, antibacterial activity studies of a new macrocyclic schiff base

2006 ◽  
Vol 43 (6) ◽  
pp. 1679-1684 ◽  
Author(s):  
H. Ibrahim Ugras ◽  
Ismet Basaran ◽  
Turgut Kilic ◽  
Umit Cakir
Keyword(s):  
Antibacterial Activity ◽  
Schiff Base ◽  
Macrocyclic Schiff Base

scholarly journals Synthesis, Spectroscopic, Molecular Structure, and Antibacterial Studies of Dibutyltin(IV) Schiff Base Complexes Derived from Phenylalanine, Isoleucine, and Glycine

2014 ◽  
Vol 2014 ◽  
pp. 1-12 ◽  
Author(s):  
Har Lal Singh ◽  
Jangbhadur Singh
Keyword(s):  
Amino Acids ◽  
Schiff Base ◽  
Schiff Bases ◽  
Molar Conductance ◽  
Schiff Base Complexes ◽  
Spectral Studies ◽  
E Coli ◽  
Elemental Analyses ◽  
In Vitro Antibacterial Activity

New series of organotin(IV) complexes and Schiff bases derived from amino acids have been designed and synthesized from condensation of1H-indole-2,3-dione, 5-chloro-1H-indole-2,3-dione, andα-amino acids (phenylalanine, isoleucine, and glycine). All compounds are characterized by elemental analyses, molar conductance measurements, and molecular weight determinations. Bonding of these complexes is discussed in terms of their UV-visible, infrared, and nuclear magnetic resonance (1H,13C, and119Sn NMR) spectral studies. The results suggest that Schiff bases behave as monobasic bidentate ligands and coordinate with dibutyltin(IV) in octahedral geometry according to the general formula [Bu2Sn(L)2]. Elemental analyses and NMR spectral data of the ligands with their dibutyltin(IV) complexes agree with their proposed distorted octahedral structures. Few representative compounds are tested for their in vitro antibacterial activity against Gram-positive (B. cereus,Staphylococcusspp.) and Gram-negative (E. coli,Klebsiellaspp.) bacteria. The results show that the dibutyltin complexes are more reactive with respect to their corresponding Schiff base ligands.

scholarly journals Metal Complexes of a Novel Schiff Base Based on Penicillin: Characterization, Molecular Modeling, and Antibacterial Activity Study

2017 ◽  
Vol 2017 ◽  
pp. 1-13 ◽  
Author(s):  
Narendra Kumar Chaudhary ◽  
Parashuram Mishra
Keyword(s):  
Thermal Stability ◽  
Antibacterial Activity ◽  
Schiff Base ◽  
Metal Complexes ◽  
Parent Drug ◽  
Molar Conductance ◽  
Kinetic Properties ◽  
Field Calculation ◽  
Tetrahedral Geometry

A novel Schiff base ligand of type HL was prepared by the condensation of amoxicillin trihydrate and nicotinaldehyde. The metal complexes of Co+2, Ni+2, Cu+2, and Zn+2 were characterized and investigated by physical and spectral techniques, namely, elemental analysis, melting point, conductivity, 1H NMR, IR, UV-Vis spectra, ESR, SEM, and mass spectrometry measurements. They were further analyzed by thermal technique (TGA/DTA) to gain better insight about the thermal stability and kinetic properties of the complexes. Thermal data revealed high thermal stability and nonspontaneous nature of the decomposition steps. The Coats-Redfern method was applied to extract thermodynamic parameters to explain the kinetic behavior. The molar conductance values were relatively low, showing their nonelectrolytic nature. The powder XRD pattern revealed amorphous nature except copper complex (1c) that crystallized in the triclinic crystal system. The EPR study strongly recommends the tetrahedral geometry of 1c. The structure optimization by MM force field calculation through ArgusLab 4.0.1 software program supports the concerned geometry of the complexes. The in vitro antibacterial activity of all the compounds, at their two different concentrations, was screened against four bacterial pathogens, namely, E. coli, P. vulgaris, K. pneumoniae, and S. aureus, and showed better activity compared to parent drug and control drug.

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