The Use of Icterometer in Assessing Neonatal Jaundice

A study was made to assess neonatal jaundice by icterometer compared with serum bilirubin concentration, which was determined by Mercko photometric test, on 98 newborns with jaundice born in the Dr. Hasan Sadikin General Hospital, Bandung, throughout October 1975 until March 1976. A good correlation between bilirubin concentration as determined by the icterometer and actual serum bilirubin concentration was found, so that the icterometer could be used in Indonesian newborns. None of the icterometer values grade 3 or less had actual serum bilirubin concentrations more than 15 mg.%, so that grade 3 or less did not necessarily require additional serum bilirubin determination. On the contrary 46.7% and 81.8% of newborns with icterometer values of grades 3½ and 4 respectively have bilirubin concentrations more than 15 mg.%. Therefore, grade 3½ or more required further photometric bilirubin determination with a view to possible treatment.

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Serum bilirubin concentration in breast-fed newborn babies at Larantuka General Hospital, East Flores

Paediatrica Indonesiana ◽

10.14238/pi41.6.2001.284-7 ◽

2001 ◽

Vol 41 (6) ◽

pp. 284

Author(s):

Tri Yasa P. ◽

Abdul Hamid S.

Keyword(s):

Weight Loss ◽

Breast Milk ◽

General Hospital ◽

Breast Feeding ◽

Serum Bilirubin ◽

Significant Risk ◽

Neonatal Hyperbilirubinemia ◽

Bilirubin Concentration ◽

Breast Fed ◽

Serum Bilirubin Concentration

Neonatal hyperbilirubinemia is a common problem not only to pediatricians but also to the parents. Breastfeeding is known as one of the factors associated with hyperbilirubinemia. The aim of the study was to determine serum bilirubin concentration and factors related to hyperbilirubinemia in breast-fed newborn babies. A cross sectional study was done on 45 well babies born at Larantuka General Hospital, East Flores, from August to October 1998. Data including personal data, frequency of breast-feeding, frequency of urination, meconium passage, and weight loss, were collected through questionnaires, presented in tables, and analyzed using chi-square test. The prevalence of hyperbilirubinemia in breast-fed babies was 13%. It was correlated significantly with the frequency of breast-feeding (p<0.01), meconium passage (p<0.02), sufficiency of breast milk (p<0.05), and weight loss (p<0.05). The significant risk factors for neonatal hyperbilirubinemia were the frequency of breast-feeding, meconium passage, sufficiency of breast milk, and weight loss. Immediate and frequent breast-feeding is recommended for the management of neonatal hyperbilirubinemia.

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Jackson Pratt Drain Fluid to Serum Bilirubin Concentration Ratio for the Diagnosis of Bile Leaks

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2008.03.349 ◽

2008 ◽

Vol 67 (5) ◽

pp. AB159

Author(s):

Peter E. Darwin ◽

Eric M. Goldberg ◽

Lance T. Uradomo

Keyword(s):

Concentration Ratio ◽

Serum Bilirubin ◽

Bilirubin Concentration ◽

Drain Fluid ◽

Bile Leaks ◽

Serum Bilirubin Concentration

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Tin-protoporphyrin in the Management of Children With Crigler-Najjar Disease

PEDIATRICS ◽

10.1542/peds.86.1.152 ◽

1990 ◽

Vol 86 (1) ◽

pp. 152-152

Author(s):

FIRMINO F. RUBALTELLI ◽

GIULIO JORI

Keyword(s):

Serum Bilirubin ◽

Bilirubin Concentration ◽

Tin Protoporphyrin ◽

Low Levels ◽

Serum Bilirubin Concentration

In Reply.— We have considered carefully the points raised by Dr McDonagh and answer as follows: Regarding points 1 and 2, Fig 2 (second plot from the bottom) of our paper clearly shows that administration of SnPp to the patient with Crigler-Najjar type 1 disease reduces the serum bilirubin concentration to values ranging between 12 and 15 mg/dL for at least a week. In the absence of SnPp treatment, the infant never reached such low levels even during sunny seasons, unless phototherapy was performed.

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Low serum bilirubin concentration is associated with coronary artery calcification (CAC)

Atherosclerosis ◽

10.1016/j.atherosclerosis.2009.02.010 ◽

2009 ◽

Vol 206 (1) ◽

pp. 287-291 ◽

Cited By ~ 44

Author(s):

Muhei Tanaka ◽

Michiaki Fukui ◽

Ki-ichiro Tomiyasu ◽

Satoshi Akabame ◽

Koji Nakano ◽

...

Keyword(s):

Coronary Artery ◽

Coronary Artery Calcification ◽

Serum Bilirubin ◽

Bilirubin Concentration ◽

Low Serum ◽

Serum Bilirubin Concentration

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YELLOW SKIN A BETTER PREDICTOR?

PEDIATRICS ◽

10.1542/peds.84.6.a45a ◽

1989 ◽

Vol 84 (6) ◽

pp. A45-A45

Author(s):

Student

Keyword(s):

Brain Damage ◽

Clinical Utility ◽

Serum Bilirubin ◽

High Serum ◽

Bilirubin Concentration ◽

Yellow Colour ◽

The Brain ◽

Reserve Albumin ◽

High Serum Bilirubin ◽

Serum Bilirubin Concentration

If kernicterus develops in an infant due to high serum bilirubin, low reserve albumin, and acidosis, bilirubin acid will also be deposited in the skin. In consequence, it seems possible that the yellow colour of the skin is correlated with that of the brain, to the extent that bilirubin deposition in the skin has occurred by precipitation of bilirubin acid. If so, the intensity of the yellow colour of the skin may be a somewhat better predictor of brain damage than the serum bilirubin concentration and measurement of the colour of the skin may theoretically be of clinical utility.

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Transcutaneous Bilirubin Measurements in Full-Term Infants

PEDIATRICS ◽

10.1542/peds.70.3.464 ◽

1982 ◽

Vol 70 (3) ◽

pp. 464-467 ◽

Cited By ~ 6

Author(s):

M. Jeffrey Maisels ◽

Sarah Conrad

Keyword(s):

Positive Predictive Value ◽

Predictive Value ◽

False Positive ◽

Neonatal Jaundice ◽

Serum Bilirubin ◽

False Negative ◽

Full Term ◽

Bilirubin Concentration ◽

Term Infants ◽

Transcutaneous Bilirubin

A total of 292 transcutaneous bilirubin (TcB) measurements were performed in 157 white full-term infants: 157 were obtained from the forehead and 135 from the midsternum. TcB measurements correlated well with serum bilirubin determinations (r = .93, P < .0001). The sensitivity of the test was 100% and the specificity 97%. It was possible to establish guidelines for the TcB measurement which identified all infants whose serum bilirubin concentrations exceeded 12.9 mg/100 ml (221 µmoles/liter) with no false-negative and only five false-positive determinations (3%). The positive predictive value for the TcB measurements was 58%. This implies that, in our population, an infant with a TcB index ≥24 has a 58% chance of having a serum bilirubin concentration >12.9 mg/100 ml. The negative predictive value was 100%. Thus, a negative test will correctly predict the absence of hyperbilirubinemia in all cases. As these measurements were obtained prospectively in a well-baby population with a prevalence of hyperbilirubinemia (>12.9 mg/100 ml) of 4.5%, the positive predictive value should be applicable to other similar populations and will, in fact, increase in populations with a higher prevalence of hyperbilirubinemia. TcB measurements can be recommended for the identification of significant neonatal jaundice in full-term infants. It is important to recognize, however, that because of potential variations in TcB meters as well as serum bilirubin measurements in different laboratories, each institution should establish its own criteria for the use of this instrument.

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