Telaprevir Causes a Rare Life Threatening Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) Syndrome During Chronic Hepatitis C Therapy: Is Obesity a Risk Factor?

2012 ◽  
Vol 107 ◽  
pp. S175 ◽  
Author(s):  
Omar Mousa ◽  
Rossa Khalaf ◽  
Rhonda Shannon ◽  
Chukwuma Egwim ◽  
Scott Zela ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Risk Factor ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Dress Syndrome ◽  
Hepatitis C Therapy ◽  
Life Threatening ◽  
Drug Rash ◽  
Systemic Symptoms

scholarly journals Drug Induced Pneumonitis Secondary to Treatment with Paritaprevir/Ritonavir/Ombitasvir and Dasabuvir (VIEKIRA PAK®) for Chronic Hepatitis C: Case Report of an Unexpected Life-Threatening Adverse Reaction

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Shih Yea Sylvia Wu ◽  
Bridget Faire ◽  
Edward Gane
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Kidney Injury ◽  
Complete Recovery ◽  
Final Diagnosis ◽  
Community Acquired Pneumonia ◽  
Drug Induced ◽  
First Case ◽  
Life Threatening

VIEKIRA PAK (ritonavir-boosted paritaprevir/ombitasvir and dasabuvir) is an approved treatment for compensated patients with genotype 1 (GT1) chronic hepatitis C virus (HCV) infection. This oral regimen has minimal adverse effects and is well tolerated. Cure rates are 97% in patients infected with HCV GT 1a and 99% in those with HCV GT 1b. We report the first case of life-threatening allergic pneumonitis associated with VIEKIRA PAK. This unexpected serious adverse event occurred in a 68-year-old Chinese female with genotype 1b chronic hepatitis C and Child-Pugh A cirrhosis. One week into treatment with VIEKIRA PAK without ribavirin, she was admitted to hospital with respiratory distress and acute kidney injury requiring intensive care input. She was initially diagnosed with community acquired pneumonia and improved promptly with intravenous antibiotics and supported care. No bacterial or viral pathogens were cultured. Following complete recovery, she recommenced VIEKIRA PAK but represented 5 days later with more rapidly progressive respiratory failure, requiring intubation and ventilation, inotropic support, and haemodialysis. The final diagnosis was drug induced pneumonitis.

scholarly journals Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C

Hepatology ◽  
2005 ◽  
Vol 42 (1) ◽  
pp. 63-71 ◽  
Author(s):  
Christophe Hézode ◽  
Françoise Roudot-Thoraval ◽  
Son Nguyen ◽  
Pascale Grenard ◽  
Boris Julien ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Risk Factor ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Cannabis Smoking

Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy

2013 ◽  
Vol 20 (12) ◽  
pp. 858-866 ◽  
Author(s):  
P. J. Clark ◽  
A. Aghemo ◽  
E. Degasperi ◽  
E. Galmozzi ◽  
T. J. Urban ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Hepatitis C Therapy ◽  
Anaemia Management ◽  
Inosine Triphosphatase

Chronic hepatitis C infection: An independent risk factor for subclinical atheromatosis

2019 ◽  
Vol 219 (6) ◽  
pp. 293-302
Author(s):  
T. Revuelto Artigas ◽  
N. Zaragoza Velasco ◽  
X. Gómez Arbones ◽  
T. Vidal Ballester ◽  
C. Piñol Felis ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Risk Factor ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Independent Risk Factor ◽  
Hepatitis C Infection

P748 CHRONIC HEPATITIS C INFECTION AS A RISK FACTOR FOR RENAL CELL CARCINOMA

2014 ◽  
Vol 60 (1) ◽  
pp. S320
Author(s):  
H.C. Gonzalez ◽  
L. Lamerato ◽  
C.G. Rogers ◽  
S.C. Gordon
Keyword(s):  
Renal Cell Carcinoma ◽  
Chronic Hepatitis ◽  
Risk Factor ◽  
Hepatitis C ◽  
Cell Carcinoma ◽  
Chronic Hepatitis C ◽  
Renal Cell ◽  
Hepatitis C Infection
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