Kinetics of Polymerase Chain Reaction Testing in Patients with Clostridium difficile Infection

2013 ◽  
Vol 108 ◽  
pp. S175
Author(s):  
Sahil Khanna ◽  
Matthew Mrazek ◽  
Patricia Kammer ◽  
Robin Patel ◽  
Darrell Pardi
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Polymerase Chain ◽  
Kinetics Of

An Evaluation of Repeat Stool Testing for Clostridium difficile Infection by Polymerase Chain Reaction

2012 ◽  
Vol 46 (10) ◽  
pp. 846-849 ◽  
Author(s):  
Sahil Khanna ◽  
Darrell S. Pardi ◽  
Jon E. Rosenblatt ◽  
Robin Patel ◽  
Patricia P. Kammer ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Chain Reaction ◽  
Polymerase Chain

Detection of Clostridium difficile Infection

2010 ◽  
Vol 31 (S1) ◽  
pp. S35-S37 ◽  
Author(s):  
John G. Bartlett
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Diagnostic Tests ◽  
Clinical Laboratory ◽  
Rapid Diagnostic Tests ◽  
Testing Methods ◽  
Chain Reaction ◽  
Immune Mechanisms ◽  
Polymerase Chain

There has been a recent surge of interest in Clostridium difficile infection, which reflects an impressive increase in the number and severity of these infections. This review addresses some of the newer methods for detection of C. difficile infection at the bedside and in the laboratory. Particularly important are the new rapid diagnostic tests that detect toxigenic C. difficile using polymerase chain reaction and the combination tests that, either simultaneously or sequentially, screen for C. difficile and test for toxins A and B. It is expected that these new testing methods will largely supplant the enzyme immunoassays for toxins, which are used by most laboratories, departments, and divisions. The present goal is to combine clinical, laboratory, and animal research related to C. difficile that reflects issues that are considered to be major contemporary challenges. Among this work is the pursuit of studies of immune mechanisms to better control this disease.

scholarly journals Substantial Variation in Hospital Rankings after Adjusting for Hospital-Level Predictors of Publicly-Reported Hospital-Associated Clostridium difficile Infection Rates

2015 ◽  
Vol 36 (4) ◽  
pp. 464-466 ◽  
Author(s):  
Rupak Datta ◽  
N. Neely Kazerouni ◽  
Jon Rosenberg ◽  
Vinh Q. Nguyen ◽  
Michael Phelan ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Clostridium Difficile ◽  
Teaching Hospitals ◽  
Substantial Variation ◽  
Infection Rates ◽  
Hospital Level ◽  
Chain Reaction ◽  
Polymerase Chain Reaction Testing ◽  
Polymerase Chain

Across 366 California hospitals, we identified hospital-level characteristics predicting increased hospital-associated Clostridium difficile infection (HA-CDI) rates including more licensed beds, teaching and long-term acute care (LTAC) hospitals, and polymerase chain reaction testing. Adjustment for these characteristics impacted rankings in 24% of teaching hospitals, 13% of community hospitals, and 11% of LTAC hospitals.Infect Control Hosp Epidemiol 2015;00(0): 1–3

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