Retrospective Study on the Use of Infliximab and Adalimumab Drug and Antibody Levels for Clinical Decision Making in IBD Patients at a University-Based Single-Center Practice

2015 ◽  
Vol 110 ◽  
pp. S833
Author(s):  
Sarah Flores ◽  
Kareem Sassi ◽  
Nimisha Parekh
2021 ◽  
Vol 12 (20) ◽  
pp. 6050-6057
Author(s):  
Xiaoyuan Liang ◽  
Wei Cai ◽  
Xingyu Liu ◽  
Ming Jin ◽  
Lingxiang Ruan ◽  
...  

2006 ◽  
Vol 16 (3) ◽  
pp. 1330-1335 ◽  
Author(s):  
L. H. Honorè ◽  
J. Hanson

In a retrospective study using univariate analysis, we identified tumor type (nonendometrioid vs endometrioid), depth of myoinvasion (MI), mode of MI (infiltrative vs cohesive), and direct anatomic invasion of the cervical wall from the isthmus as significant positive risk factors for intramyometrial lymphvascular space involvement (LVSI). On multivariate analysis, tumor grade, depth of MI, and mode of MI retained their significance. We created a grid for the relative risks of LVSI with respect to these variables individually or in combination. We suggest that our indirect estimate of the risk of LVSI can help in assessing prognosis and determining the need for adjuvant therapy whenever LVSI is important in clinical decision making, but its pathologic diagnosis is uncertain.


2011 ◽  
Vol 20 (4) ◽  
pp. 121-123
Author(s):  
Jeri A. Logemann

Evidence-based practice requires astute clinicians to blend our best clinical judgment with the best available external evidence and the patient's own values and expectations. Sometimes, we value one more than another during clinical decision-making, though it is never wise to do so, and sometimes other factors that we are unaware of produce unanticipated clinical outcomes. Sometimes, we feel very strongly about one clinical method or another, and hopefully that belief is founded in evidence. Some beliefs, however, are not founded in evidence. The sound use of evidence is the best way to navigate the debates within our field of practice.


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