Adenoma Detection Through Deep Learning: 2017 Presidential Poster Award

2017 ◽  
Vol 112 ◽  
pp. S136 ◽  
Author(s):  
William E. Karnes ◽  
Andrew Ninh ◽  
Gregor Urban ◽  
Pierre Baldi
2021 ◽  
Vol 108 (Supplement_3) ◽  
Author(s):  
L F Sánchez Peralta ◽  
J F Ortega Morán ◽  
Cr L Saratxaga ◽  
J B Pagador ◽  
A Picón ◽  
...  

Abstract INTRODUCTION Deep learning techniques have significantly contributed to the field of medical imaging analysis. In case of colorectal cancer, they have shown a great utility for increasing the adenoma detection rate at colonoscopy, but a common validation methodology is still missing. In this study, we present preliminary efforts towards the definition of a validation framework. MATERIAL AND METHODS Different models based on different backbones and encoder-decoder architectures have been trained with a publicly available dataset that contains white light and NBI colonoscopy videos, with 76 different lesions from colonoscopy procedures in 48 human patients. A computer aided detection (CADe) demonstrator has been implemented to show the performance of the models. RESULTS This CADe demonstrator shows the areas detected as polyp by overlapping the predicted mask on the endoscopic image. It allows selecting the video to be used, among those from the test set. Although it only present basic features such as play, pause and moving to the next video, it easily loads the model and allows for visualization of results. The demonstrator is accompanied by a set of metrics to be used depending on the aimed task: polyp detection, localization and segmentation. CONCLUSIONS The use of this CADe demonstrator, together with a publicly available dataset and predefined metrics will allow for an easier and more fair comparison of methods. Further work is still required to validate the proposed framework.


2018 ◽  
Vol 113 (Supplement) ◽  
pp. S276
Author(s):  
Thanh-Truc Le ◽  
Mohammad Bilal ◽  
Yamam I. Al-Saadi ◽  
Shailendra Singh ◽  
Praveen Guturu

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e036423
Author(s):  
Zhigang Song ◽  
Chunkai Yu ◽  
Shuangmei Zou ◽  
Wenmiao Wang ◽  
Yong Huang ◽  
...  

ObjectivesThe microscopic evaluation of slides has been gradually moving towards all digital in recent years, leading to the possibility for computer-aided diagnosis. It is worthwhile to know the similarities between deep learning models and pathologists before we put them into practical scenarios. The simple criteria of colorectal adenoma diagnosis make it to be a perfect testbed for this study.DesignThe deep learning model was trained by 177 accurately labelled training slides (156 with adenoma). The detailed labelling was performed on a self-developed annotation system based on iPad. We built the model based on DeepLab v2 with ResNet-34. The model performance was tested on 194 test slides and compared with five pathologists. Furthermore, the generalisation ability of the learning model was tested by extra 168 slides (111 with adenoma) collected from two other hospitals.ResultsThe deep learning model achieved an area under the curve of 0.92 and obtained a slide-level accuracy of over 90% on slides from two other hospitals. The performance was on par with the performance of experienced pathologists, exceeding the average pathologist. By investigating the feature maps and cases misdiagnosed by the model, we found the concordance of thinking process in diagnosis between the deep learning model and pathologists.ConclusionsThe deep learning model for colorectal adenoma diagnosis is quite similar to pathologists. It is on-par with pathologists’ performance, makes similar mistakes and learns rational reasoning logics. Meanwhile, it obtains high accuracy on slides collected from different hospitals with significant staining configuration variations.


2020 ◽  
Vol 13 ◽  
pp. 263177452093522
Author(s):  
Shraddha Gulati ◽  
Andrew Emmanuel ◽  
Mehul Patel ◽  
Sophie Williams ◽  
Amyn Haji ◽  
...  

Artificial intelligence is a strong focus of interest for global health development. Diagnostic endoscopy is an attractive substrate for artificial intelligence with a real potential to improve patient care through standardisation of endoscopic diagnosis and to serve as an adjunct to enhanced imaging diagnosis. The possibility to amass large data to refine algorithms makes adoption of artificial intelligence into global practice a potential reality. Initial studies in luminal endoscopy involve machine learning and are retrospective. Improvement in diagnostic performance is appreciable through the adoption of deep learning. Research foci in the upper gastrointestinal tract include the diagnosis of neoplasia, including Barrett’s, squamous cell and gastric where prospective and real-time artificial intelligence studies have been completed demonstrating a benefit of artificial intelligence–augmented endoscopy. Deep learning applied to small bowel capsule endoscopy also appears to enhance pathology detection and reduce capsule reading time. Prospective evaluation including the first randomised trial has been performed in the colon, demonstrating improved polyp and adenoma detection rates; however, these appear to be relevant to small polyps. There are potential additional roles of artificial intelligence relevant to improving the quality of endoscopic examinations, training and triaging of referrals. Further large-scale, multicentre and cross-platform validation studies are required for the robust incorporation of artificial intelligence–augmented diagnostic luminal endoscopy into our routine clinical practice.


Endo-Praxis ◽  
2021 ◽  
Vol 37 (01) ◽  
pp. 37-42
Author(s):  
Andres Rademacher ◽  
Siegbert Faiss

ZusammenfassungDurch die Vorsorgekoloskopie lässt sich die Inzidenz und die Sterblichkeit des kolorektalen Karzinoms effektiv senken. Die Adenomdetektionsrate (ADR = engl. adenoma detection rate) stellt ein entscheidendes Qualitätskriterium der Vorsorgekoloskopie dar. Die Nutzung computerbasierender Assistenzsysteme in der Endoskopie bietet große Chancen, die Adenomdetektionsrate weiter zu steigern und für eine weitere Qualitätssicherung in der Endoskopie zu sorgen.Die theoretischen Grundlagen der künstlichen Intelligenz wurden bereits in den 1950er-Jahren gelegt, eine breite Anwendung ist jedoch erst jetzt durch die Entwicklung schneller Computer und die Verfügbarkeit großer digitaler Datenmengen möglich. Das Deep Learning (dt. mehrschichtiges Lernen oder tiefes Lernen) stellt eine Form des maschinellen Lernens dar, bei dem durch Nutzung eines künstlichen neuronalen Netzwerks nach einer Lernphase komplexe Aufgaben gelöst werden können. Es eignet sich für Anwendungen, die für das menschliche Gehirn keine große Anstrengung darstellen (wie z. B. Gesichts- oder Spracherkennung), die jedoch mit konventionellen Methoden sehr aufwendig zu programmieren sind.Für den Einsatz in der Endoskopie wurden auf künstlicher Intelligenz basierende Systeme zur computergestützten Polypendetektion (engl. computer aided Detection = CADe), computergestützte Diagnose (engl. computer aided diagnosis = CADx) und zum computergestützten Monitoring (engl. computer aided monitoring = CADm) erfolgreich in Studien getestet. Erste kommerzielle Systeme zur Polypendetektion und zur optischen Biopsie im Kolon sind bereits erhältlich und konnten in Studien eine Steigerung der ADR durch Einsatz der künstlichen Intelligenz belegen.Computergestützte Assistenzsysteme auf Basis des Deep Learning könnten in naher Zukunft zum Standard in der Endoskopie werden, um eine optimale Polypendetektion, akkurate Diagnosestellung und objektives Untersuchungsmonitoring zu gewährleisten.


Sign in / Sign up

Export Citation Format

Share Document