scholarly journals Physical Activity Profile and Risk of Type 2 Diabetes Mellitus in Udupi (India) Population

2022 ◽  
Vol 24 (5) ◽  
pp. 456-460
Author(s):  
N. Ladha ◽  
A. Maiya ◽  
N. Prabhu ◽  
A.S. Kumar ◽  
S. G ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Risk Score ◽  
Activity Levels ◽  
Middle Income ◽  
Glucose Levels ◽  
Highly Active

Background: Throught the world, More than 75% of adults with type 2 diabetes mellitus (T2DM) live in low and middle-income countries. Amongst which 69.2 million of these adults live in India. Its been shown that, as level of physical activity increases, risk of developing T2DM decreases by 15-60%. Many studies are conducted to find the risk of development of T2DM in the coastal areas of Karnataka. However, the screening of people living in Udupi was not carried out.Aim: To find out the risk for the development of T2DM using IDRS and physical activity levels in Udupi population.Material and Methods: In the current study, we included participants who were asymptomatic and undiagnosed to be having T2DM. The participants age ranged between 30–65 yrs. Participants with the history of any neurological conditions and women who were pregnant at the time of screening were excluded. We recorded random blood glucose levels of the participants following which the risk score was obtained using the Indian Diabetes Risk Score (IDRS) and the participants were classified as high risk (score ≥60), moderate risk score (30–50) and low risk (score <30). The level of physical ­activity was measured using Global Physical Activity Questionnaire.Results: The study included 23,960 participants from Udupi district, Karnataka. Based on IDRS risk stratification, 1.5%, 17.9%, 27.5% of the participants with the age ange of 30–35 yrs, 36–50 yrs and more than 50 yrs respectively had higher risk of developing T2DM. According to GPAQ score 14% of the participants were following sedentary lifestyle, 27.6% of the were minimally active, 53.7% were very active, and 4.6% were highly active.Conclusion: From the current study we conclude that 46.9% of participants had a higher risk of developing T2DM in future who are living in Udupi district.

scholarly journals Assessing the risk of developing type 2 diabetes mellitus among medical students in Chennai using Indian diabetes risk score

2017 ◽  
Vol 4 (7) ◽  
pp. 2366
Author(s):  
Gopalakrishnan S. ◽  
Rama R. ◽  
Muthulakshmi M.
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Medical Students ◽  
Risk Score ◽  
Family History Of Diabetes ◽  
History Of ◽  
Diabetes Risk Score

Background: Prevalence of type 2 diabetes mellitus [T2DM] is becoming alarmingly high among younger age groups impacting on their physical, mental, social and academic wellbeing and therefore warrants early detection and prevention. The Indian diabetes risk score [IDRS] is an efficient screening tool to detect the high risk individuals at an early stage. Objective of this study is to assess the level of risk of developing T2DM among medical students using the IDRS.Methods: This cross sectional study was done using the MDRF-IDR Score to identify the ‘at risk’ medical students. Simple random sampling was used and data collected from among the 251 willing students. Their risk score was calculated using a structured questionnaire. Data was analysed using SPSS Ver.15 software.Results: This study shows that about 57.4% are moderately at risk and 2% are at high risk for developing diabetes mellitus. About 86.1% medical students belonged to nuclear family, 42.6% had family history of diabetes mellitus, 76.5% carried out moderate physical activity and 50.2% were overweight / obese. Family history of diabetes, lack of physical activity and overweight / obesity were found to be potential risk factors for developing diabetes mellitus (p<0.0001).Conclusions: This study reveals that in the existing urban lifestyle, adolescents and youths are highly vulnerable to diabetes mellitus. Primordial and primary prevention are the most effective preventive measure and therefore, appropriate and stringent lifestyle modifications need to be implemented in order to minimize the risk of developing the disease later in life.

scholarly journals The impact of mental and somatic stressors on physical activity and sedentary behaviour in adults with type 2 diabetes mellitus: a diary study

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e11579
Author(s):  
Louise Poppe ◽  
Annick L. De Paepe ◽  
Dimitri M.L. Van Ryckeghem ◽  
Delfien Van Dyck ◽  
Iris Maes ◽  
...  
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Sedentary Behaviour ◽  
Activity Levels ◽  
Mixed Effect ◽  
Mixed Effect Models ◽  
The Impact

Background Adopting an active lifestyle is key in the management of type 2 diabetes mellitus (T2DM). Nevertheless, the majority of individuals with T2DM fails to do so. Additionally, individuals with T2DM are likely to experience mental (e.g., stress) and somatic (e.g., pain) stressors. Research investigating the link between these stressors and activity levels within this group is largely lacking. Therefore, current research aimed to investigate how daily fluctuations in mental and somatic stressors predict daily levels of physical activity (PA) and sedentary behaviour among adults with T2DM. Methods Individuals with T2DM (N = 54) were instructed to complete a morning diary assessing mental and somatic stressors and to wear an accelerometer for 10 consecutive days. The associations between the mental and somatic stressors and participants’ levels of PA and sedentary behaviour were examined using (generalized) linear mixed effect models. Results Valid data were provided by 38 participants. We found no evidence that intra-individual increases in mental and somatic stressors detrimentally affected participants’ activity levels. Similarly, levels of sedentary behaviour nor levels of PA were predicted by inter-individual differences in the mental and somatic stressors.

Gender Differences in Physical Activity Levels of Older People With Type 2 Diabetes Mellitus

2016 ◽  
Vol 13 (4) ◽  
pp. 409-415 ◽  
Author(s):  
Joan Kelly ◽  
Katrina Edney ◽  
Chris Moran ◽  
Velandai Srikanth ◽  
Michele Callisaya
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Older People ◽  
Activity Levels ◽  
Physical Activity Levels ◽  
Steps Per Day ◽  
Multivariable Regression

Background:Physical activity (PA) is important in managing Type 2 Diabetes Mellitus (T2DM). This study aimed to determine 1) the number of daily steps taken by older people with T2DM, 2) if T2DM is associated with taking fewer steps per day and less likelihood of meeting PA guidelines, and 3) whether these associations are modified by age or gender.Methods:PA was obtained by pedometer from 2 cohorts of older adults with and without T2DM. Multivariable regression was used to determine associations between T2DM, mean steps per day and meeting a guideline equivalent (7 100 steps per day).Results:There were 293 participants with T2DM (mean age 67.6 ± 6.8 years) and 336 without T2DM (mean age 72.1 ± 7.1 years). In women, T2DM was associated with fewer mean steps per day (β = –1306.4; 95% CI –2052.5, –560.3; P = .001) and not meeting the PA guidelines (OR 0.51; 95% CI 0.28, 0.92; P = .03). Associations were not significant in men (P > .05). Only 29.7% of those with T2DM and 33.3% of those without T2DM met PA guidelines.Conclusions:Greater focus is needed on how to maintain and increase PA in older age with particular focus on women with T2DM.

scholarly journals The frequency of Tim-3 on circulating Tfh cells was increased in type 2 diabetes mellitus patients

2020 ◽  
Vol 18 ◽  
pp. 205873922098280
Author(s):  
Shuai Guo ◽  
Xujie Yu ◽  
Limei Wang ◽  
Jing Jing ◽  
Yuanyuan Sun ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
High Glucose ◽  
C Peptide ◽  
Glucose Levels ◽  
Tfh Cells ◽  
Fasting Plasma ◽  
Healthy Donors

Type 2 diabetes mellitus (T2DM) is a chronic, low-grade inflammation disease. T follicular helper (Tfh) cells and T cell immunoglobulin and mucin domain 3 (Tim-3) are implicated in many immune diseases. This study aims to explore whether Tim-3 expression on Tfh cells is associated with T2DM progression. White blood cells (WBCs) were harvested from 30 patients with T2DM and 20 healthy donors. The abundance of circulating Tfh cells (cTfh) and the frequency of Tim-3 were analyzed by flow cytometry. Levels of fasting plasma glucose (FPG), insulin, hemoglobin A1C (HbA1C), and fasting plasma C-peptide were measured. Body mass index (BMI) and diabetes duration were also recorded. Patients with T2DM had higher numbers of cTfh cells. In addition, cTfh cells showed a negative correlation with HbA1C and diabetes duration, a positive correlation with fasting plasma C-peptide. The frequency of Tim-3 on cTfh cells was higher among T2DM patients compared with healthy donors. The in vitro experiment showed that high glucose levels increased the abundance cTfh cells but had no effect on Tim-3 expression. Our results suggest that cTfh cells and associated Tim-3 frequency may contribute to the progression of T2DM, and high glucose levels may influence cTfh cells directly.

scholarly journals Pharmaceutical hit of anti type 2 Diabetes mellitus on the phenolic extract of Malaka (Phyllanthus emblica L.) flesh

2019 ◽  
Vol 5 (1) ◽  
Author(s):  
Musri Musman ◽  
Mauli Zakia ◽  
Ratu Fazlia Inda Rahmayani ◽  
Erlidawati Erlidawati ◽  
Safrida Safrida
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Body Weight ◽  
Blood Glucose ◽  
Phyllanthus Emblica ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Phenolic Extract

Abstract Background Ethnobotany knowledge in a community has shaped local wisdom in utilizing plants to treat diseases, such as the use of Malaka (Phyllanthus emblica) flesh to treat type 2 diabetes. This study presented evidence that the phenolic extract of the Malaka flesh could reduce blood sugar levels in the diabetic induced rats. Methods The phenolic extract of the P. emblica was administrated to the glucose-induced rats of the Wistar strain Rattus norvegicus for 14 days of treatment where the Metformin was used as a positive control. The data generated were analyzed by the two-way ANOVA Software related to the blood glucose level and by SAS Software related to the histopathological studies at a significant 95% confidence. Results The phenolic extract with concentrations of 100 and 200 mg/kg body weight could reduce blood glucose levels in diabetic rats. The post hoc Dunnet test showed that the administration of the extract to the rats with a concentration of 100 mg/kg body weight demonstrated a very significant decrease in blood glucose levels and repaired damaged cells better than administering the extract at a concentration of 200 mg/kg weight body. Conclusion The evidence indicated that the phenolic extract of the Malaka flesh can be utilized as anti type 2 Diabetes mellitus without damaging other organs.

Efficacy of a pedometer-based physical activity program on parameters of diabetes control in type 2 diabetes mellitus

Metabolism ◽  
2006 ◽  
Vol 55 (10) ◽  
pp. 1382-1387 ◽  
Author(s):  
Paul Araiza ◽  
Hilary Hewes ◽  
Carrie Gashetewa ◽  
Chantal A. Vella ◽  
Mark R. Burge
Keyword(s):  
Physical Activity ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetes Control ◽  
Physical Activity Program ◽  
Activity Program
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