scholarly journals A prospective pilot study on the effects of endoscopic sinus surgery on upper and lower airway performance

2021 ◽  
Vol 41 (6) ◽  
pp. 544-549
Author(s):  
Silvia Atzei ◽  
Andrea Melis ◽  
Laura Maria De Luca ◽  
Maurizio Gaetano Filippo Macciotta ◽  
Valentina Scano ◽  
...  
2013 ◽  
Vol 6 (1) ◽  
pp. 32-40 ◽  
Author(s):  
NV Deepthi ◽  
Indudharan R Menon

ABSTRACT Background Chronic rhinosinusitis (CRS) is diagnosed on the basis of symptoms, nasal endoscopic findings and computed tomography of the paranasal sinuses (CT PNS). Where indicated, functional endoscopic sinus surgery (FESS) is the surgical treatment. Objective To determine correlations between subjective symptom severity and objective endoscopic and radiologic findings in CRS and to compare these before and after FESS. Materials and methods Analysis of prospectively collected data of 20 patients undergoing FESS at a tertiary care medical center followed up for a minimum period of 6 months after surgery. RSI questionnaire-based symptom score, Lund-Mackay system-based endoscopic and CT finding scores were recorded preoperatively and at 8 weeks and 6 months postoperatively. Results Significant positive correlation was noted between the three parameters before surgery, especially endoscopic and radiological scores (r = 0.94 in the latter, p < 0.01 in all three). Postoperative improvement was statistically significant for all three parameters, even at the 6 months stage (p < 0.001). Postoperative correlations reduced significantly, especially between endoscopic and radiological scores. Conclusion This study showed the relevance of objective evaluation of routine parameters of CRS, preoperatively. It also confirmed the usefulness of FESS in indicated cases, in terms of statistical improvement of these parameters. However, repeat CT scans and the methods of scoring used by us may not be equally applicable in the long-term postoperative scenario. How to cite this article Deepthi NV, Menon UK, Menon IR. Correlations and Comparison between Repeat Computed Tomography Scores, Endoscopy Scores and Symptomatic Improvement before and after Endoscopic Sinus Surgery: A Pilot Study. Clin Rhinol An Int J 2013;6(1):32-40.


2007 ◽  
Vol 264 (10) ◽  
pp. 1171-1174 ◽  
Author(s):  
P. D. Karkos ◽  
T. Thinakararajan ◽  
P. Goodyear ◽  
V. R. Srinivasan

2021 ◽  
pp. 014556132110320
Author(s):  
Tetsuya Terada ◽  
Takaki Inui ◽  
Kou Moriyama ◽  
Keiki Noro ◽  
Yusuke Kikuoka ◽  
...  

Objective: To confirm the relevance of upper and lower airway inflammation in eosinophilic chronic rhinosinusitis (ECRS), the effects of endoscopic sinus surgery (ESS) on lower airway functions and inflammation need to be examined in ECRS patients. Methods: Chronic rhinosinusitis patients with nasal polyps (25 non-ECRS, 28 ECRS) were enrolled. The 12 patients in the ECRS group had comorbid asthma, in contrast to none in the non-ECRS group. We divided ECRS patients into 2 groups of ECRS with and without asthma. Clinical markers, including fraction of exhaled nitric oxide (FeNO), respiratory functions, and the Asthma Control Test (ACT) questionnaire, were investigated before and after ESS. Results: The FeNO levels in the ECRS with asthma group decreased after ESS. The mean FeNO levels in this group were 56.3 ppb before ESS and 24.9, 25.1, 25.0, and 15.5 ppb 1, 2, 3, and 4 months, respectively, after ESS. The mean forced expiratory rates in 1 second before and after ESS were 67.6% and 73.0%, respectively. The mean maximal expiratory flow rates at 50% of the vital capacity before and after ESS were 45.8% and 58.0%, respectively. Significant differences were observed in respiratory functions before and after ESS. The mean ACT scores in the ECRS with asthma group before and after ESS were 17.5 and 23.5, respectively. The ACT scores were significantly higher after than before ESS. Conclusions: The present results indicate that ECRS and bronchial asthma are common eosinophilic airway inflammatory diseases, and ESS for eosinophilic sinusitis may improve lower airway function.


Author(s):  
Dameshwa S. Lyngdoh ◽  
Subrat Kumar Behera ◽  
Smruti Swain ◽  
Manoranjan Pattnaik

<p class="abstract"><strong>Background:</strong> The human upper and lower respiratory tract share a close relationship in respect to existence of diseases. The objectives of this study were to evaluate the outcome of endoscopic sinus surgery with the Lund- Mackay staging system and to find any objective changes between the pre and post-operative pulmonary function test values in patients with chronic rhinosinusitis undergoing endoscopic sinus surgery.</p><p class="abstract"><strong>Methods:</strong> A total of 50 patients of CRSwNP refractory to maximal medical treatment (for 1 month) planned for endoscopic sinus surgery were included in the study. Results were assessed on the basis of pre and post-operative endoscopic and CT scores and PFT (FEV1, FVC and FEV1/FVC) values.  </p><p class="abstract"><strong>Results:</strong> Postoperatively, Lund Mackay endoscopic and CT scores improved from the preoperative values, which were statistically significant with p values&lt;0.05. Comparing FEV1/FVC, FVC and FEV1 values in three situations- preoperative versus postoperative 1 month, preoperative versus postoperative 3<sup>rd</sup> month and post-operative 1<sup>st</sup> month versus postoperative 3<sup>rd</sup> month, the difference between the means were found to be statistically significant (p=0.000), except for FVC between postoperative 3<sup>rd</sup> month and 1<sup>st</sup> month.</p><p class="abstract"><strong>Conclusions:</strong> This study provides objective evidence that patients with CRSwNP may have non clinical lower airway disease detected by PFT and ESS is effective in improvement of both nasal and lower airway disease as evident from the improvements in PFT values.</p>


2012 ◽  
Vol 26 (5) ◽  
pp. 409-413 ◽  
Author(s):  
Scott D. Burge ◽  
Leon Bunegin ◽  
Erik K. Weitzel ◽  
K. Christopher McMains

2004 ◽  
Vol 124 (2) ◽  
pp. 176-178 ◽  
Author(s):  
Paul S. White ◽  
Ramez Nassif ◽  
Hesham Saleh ◽  
Timothy Drew

2014 ◽  
Vol 4 (7) ◽  
pp. 542-547 ◽  
Author(s):  
Katarzyna Wawrzyniak ◽  
Pawel K. Burduk ◽  
Jacek B. Cywinski ◽  
Krzysztof Kusza ◽  
Wojciech Kazmierczak

2014 ◽  
Vol 7 (2) ◽  
pp. 52-57
Author(s):  
Nishi Sonkhya ◽  
Kalpana Sharma

ABSTRACT There has been an increasing awareness of the inter-relationship between inflammatory disease of the upper and lower airway. Both epidemiological and physiological data suggest that the respiratory tract, from the middle ear mucosa, through the nose and sinuses, and into the pulmonary tree behave as an integerated unit. Recent progress in understanding the biology of airway disease has identified that systemic inflammatory responses play a critical and integerating role in these diseases. The role of sinus surgery in the management of asthma patients has been a matter of debate for many years. We are presenting a well-designed prospective, controlled study in 50 patients with asthma and chronic rhinosinusitis (CRS) with nasal polyposis who were submitted to either functional endoscopic sinus surgery (FESS) or medical therapy. How to cite this article Sonkhya N, Sharma K. Functional Endoscopic Sinus Surgery in Patients with Chronic Rhinosinusitis and Polyposis and Asthma. Clin Rhinol An Int J 2014;7(2):52-57.


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