scholarly journals Impact of type 2 diabetes on cardiorespiratory function and exercise performance

2017 ◽  
Vol 5 (4) ◽  
pp. e13145 ◽  
Author(s):  
Joanie Caron ◽  
Gregory R. duManoir ◽  
Lawrence Labrecque ◽  
Audrey Chouinard ◽  
Annie Ferland ◽  
...  
2016 ◽  
Author(s):  
Joanie Caron ◽  
Gregory R. duManoir ◽  
Lawrence Labrecque ◽  
Audrey Chouinard ◽  
Annie Ferland ◽  
...  

AbstractThe aim of this study was to examine the impact of well-controlled uncomplicated type 2 diabetes (T2D) on exercise performance. Six obese sedentary men with T2D and 7 control participants without diabetes matched for age, sex and body mass index were recruited. Anthropometric characteristics, blood samples, resting cardiac and pulmonary functions and maximal oxygen uptake (VO2max) and ventilatory threshold were measured on a first visit. On the four subsequent visits, participants performed step transitions (6 min) of moderate-intensity exercise on an upright cycle ergometer from unloaded pedaling to 80 % of ventilatory threshold. VO2(τVO2) and HR (τHR) kinetics were characterized with a mono-exponential model. VO2max (27.8±4.0 vs. 27.5±5.3 ml kg-1min-1; p=0.95), τVO2(43±6 vs. 43±10 s; p=0.73) and τHR (42±17 vs. 43±13 s; p=0.94) were similar between diabetics and controls respectively. The remaining variables were also similar between groups. These results suggest that well-controlled T2D is not associated with a reduction in VO2max or slower τVO2and τHR.


Author(s):  
Michael Quartuccio ◽  
Swaytha Yalamanchi ◽  
Sherita Hill Golden ◽  
Judith G. Regensteiner ◽  
Rita Rastogi Kalyani

2015 ◽  
Vol 47 (1) ◽  
pp. 58-65 ◽  
Author(s):  
JUDITH G. REGENSTEINER ◽  
TIMOTHY A. BAUER ◽  
AMY G. HUEBSCHMANN ◽  
LEAH HERLACHE ◽  
HOWARD D. WEINBERGER ◽  
...  

2016 ◽  
Vol 25 ◽  
pp. S86-S87
Author(s):  
T. Roberts ◽  
A. Burns ◽  
R. MacIsaac ◽  
D. Mooney ◽  
D. Prior ◽  
...  

2020 ◽  
Vol 26 (30) ◽  
pp. 3760-3767 ◽  
Author(s):  
Melissa A. Luse ◽  
Emily M. Heiston ◽  
Steven K. Malin ◽  
Brant E. Isakson

Endothelial dysfunction is a hallmark of type 2 diabetes that can have severe consequences on vascular function, including hypertension and changes in blood flow, as well as exercise performance. Because endothelium is also the barrier for insulin movement into tissues, it acts as a gatekeeper for transport and glucose uptake. For this reason, endothelial dysfunction is a tempting area for pharmacological and/or exercise intervention with insulin-based therapies. In this review, we describe the current state of drugs that can be used to treat endothelial dysfunction in type 2 diabetes and diabetes-related diseases (e.g., obesity) at the molecular levels, and also discuss their role in exercise.


2015 ◽  
Vol 3 (1) ◽  
pp. e000124 ◽  
Author(s):  
A G Huebschmann ◽  
W M Kohrt ◽  
L Herlache ◽  
P Wolfe ◽  
S Daugherty ◽  
...  

2011 ◽  
Vol 152 (1) ◽  
pp. 143-146 ◽  
Author(s):  
Dogan Erdogan ◽  
Salaheddin Akcay ◽  
I. Hakkı Ersoy ◽  
Atilla Icli ◽  
Habil Yucel ◽  
...  

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