scholarly journals Computer aided tool design for micro-ECM

2020 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Pratik R. Shah ◽  
S.S. Pande
Keyword(s):  
Tool Design ◽  
Micro Ecm ◽  
Computer Aided

scholarly journals Computer aided tool design for micro-ECM

2020 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Pratik R. Shah ◽  
S.S. Pande
Keyword(s):  
Tool Design ◽  
Micro Ecm ◽  
Computer Aided

scholarly journals Three Out of Two

2001 ◽  
Vol 123 (09) ◽  
pp. 60-63 ◽  
Author(s):  
Jean Thilmany
Keyword(s):  
Computer Aided Design ◽  
Tool Design ◽  
Software Systems ◽  
Full Potential ◽  
Drawing Tool ◽  
Cad Systems ◽  
3D Cad ◽  
Computer Aided ◽  
General Contractors ◽  
Aided Design

This article reviews computer-aided design (CAD) software that is meant to function as more than a drawing tool; design offices and general contractors are still learning how to take advantage of its full potential even as the software systems mature. CAD systems are used to sell products before they are produced, to warehouse past designs in a central library, and to describe an intended design to a parts supplier. Traditional wisdom holds that 2D CAD systems are best suited to products with simple geometries that can be easily represented without considerable interpretive errors, products such as the nozzles. Often, 2D drawings can be ambiguous and are open to errors in interpretation, especially in cases of complex designs, according to the Queensland Manufacturing Institute (QMI) report. Century Tool wanted to use the 3D CAD software to check for interferences in the design of a part a customer had charged Century Tool with building.

CAPTD: A Low-Cost Integrated Computer Aided Design System for Press Tool Design

1993 ◽  
Vol 207 (2) ◽  
pp. 117-127 ◽  
Author(s):  
H S Ismail ◽  
K K B Hon ◽  
K Huang
Keyword(s):  
Programming Languages ◽  
Computer Aided Design ◽  
Low Cost ◽  
Tool Design ◽  
Design System ◽  
Press Tool ◽  
Industry Standard ◽  
C Programming ◽  
Computer Aided ◽  
Aided Design

This paper describes the structure and operation of a low-cost computer aided design system for press tool design (CAPTD). The system is a collection of integrated industry standard microcomputer packages and purpose-built programs. The packages include AutoCad 11, for the input of workpiece geometry and the output of the press tool part and assembly drawings, and dBase IV for the decision support, the selection of press tool components and generating output reports. A purpose built ‘C’ program is also developed for the layout and nesting of the workpiece. The system is driven by a set of press tool design rules implemented in both the dBase IV and ‘C’ programming languages. The system is developed to run on 80386SX or higher based IBM-compatible microcomputers.

Computer-aided methods for 3-D visualization of serial sections and thick biological specimens

1992 ◽  
Vol 50 (2) ◽  
pp. 1060-1061
Author(s):  
Mark Ellisman ◽  
Maryann Martone ◽  
Gabriel Soto ◽  
Eleizer Masliah ◽  
David Hessler ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Three Dimensional ◽  
Neuritic Plaque ◽  
Dimensional Structure ◽  
Data Sets ◽  
Molecular Physiology ◽  
Research Activities ◽  
Computer Aided ◽  
Dimensional Reconstruction

Structurally-oriented biologists examine cells, tissues, organelles and macromolecules in order to gain insight into cellular and molecular physiology by relating structure to function. The understanding of these structures can be greatly enhanced by the use of techniques for the visualization and quantitative analysis of three-dimensional structure. Three projects from current research activities will be presented in order to illustrate both the present capabilities of computer aided techniques as well as their limitations and future possibilities.The first project concerns the three-dimensional reconstruction of the neuritic plaques found in the brains of patients with Alzheimer's disease. We have developed a software package “Synu” for investigation of 3D data sets which has been used in conjunction with laser confocal light microscopy to study the structure of the neuritic plaque. Tissue sections of autopsy samples from patients with Alzheimer's disease were double-labeled for tau, a cytoskeletal marker for abnormal neurites, and synaptophysin, a marker of presynaptic terminals.

Three-Dimensional Subcellular Organization of Hepatocytes in Intact Liver: Simultaneous Visualization of Cytoskeletal and Membrane Markers by Confocal Microscopy

1996 ◽  
Vol 54 ◽  
pp. 288-289
Author(s):  
Greg V. Martin ◽  
Ann L. Hubbard
Keyword(s):  
Three Dimensional ◽  
Integral Membrane Proteins ◽  
Polarized Secretion ◽  
Microscope Images ◽  
Computer Aided ◽  
Intracellular Organelles ◽  
Cytoskeletal Elements ◽  
Simultaneous Visualization

The microtubule (MT) cytoskeleton is necessary for many of the polarized functions of hepatocytes. Among the functions dependent on the MT-based cytoskeleton are polarized secretion of proteins, delivery of endocytosed material to lysosomes, and transcytosis of integral plasma membrane (PM) proteins. Although microtubules have been shown to be crucial to the establishment and maintenance of functional and structural polarization in the hepatocyte, little is known about the architecture of the hepatocyte MT cytoskeleton in vivo, particularly with regard to its relationship to PM domains and membranous organelles. Using an in situ extraction technique that preserves both microtubules and cellular membranes, we have developed a protocol for immunofluorescent co-localization of cytoskeletal elements and integral membrane proteins within 20 µm cryosections of fixed rat liver. Computer-aided 3D reconstruction of multi-spectral confocal microscope images was used to visualize the spatial relationships among the MT cytoskeleton, PM domains and intracellular organelles.

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