scholarly journals The effectiveness of dapagliflozin for sleep-disordered breathing among Japanese patients with obesity and type 2 diabetes mellitus

2018 ◽  
Vol 65 (9) ◽  
pp. 953-961 ◽  
Author(s):  
Shinya Furukawa ◽  
Teruki Miyake ◽  
Hidenori Senba ◽  
Takenori Sakai ◽  
Eri Furukawa ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Sleep Disordered Breathing ◽  
Japanese Patients ◽  
Disordered Breathing

Characteristics of sleep-disordered breathing in Japanese patients with type 2 diabetes mellitus

Metabolism ◽  
2010 ◽  
Vol 59 (5) ◽  
pp. 690-696 ◽  
Author(s):  
Susumu Kashine ◽  
Ken Kishida ◽  
Tohru Funahashi ◽  
Yasuhiko Nakagawa ◽  
Michio Otuki ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Sleep Disordered Breathing ◽  
Japanese Patients ◽  
Disordered Breathing

scholarly journals Sleep Disordered Breathing in Patient with Type 2 Diabetes Mellitus and its Association with Diabetic Retinopathy: Single Center Study

2019 ◽  
Vol 2 (1) ◽  
pp. 160-163
Author(s):  
Milesh Jung Sijapati ◽  
Minalma Pandey ◽  
Poojyashree Karki ◽  
Nirupama Khadka
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Obstructive Sleep Apnea ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Retinopathy ◽  
Sleep Apnea ◽  
Sleep Disordered Breathing ◽  
Obstructive Sleep ◽  
Disordered Breathing

Introduction: Sleep-disordered breathing comprises of obstructive sleep apnea, central sleep apnea, and periodic breathing. There is a link between obesity diabetes and sleep apnea with its association with retinopathy. Therefore this study was done to find out the association of sleep-disordered breathing in uncontrolled diabetes mellitus and association with retinopathy.Materials and Methods: This study was done from 2015 September to 2018 September in Sleep center, Nepal.  Patients diagnosed with Type 2 diabetes mellitus were included. Diabetes mellitus was diagnosed as blood sugar fasting ≥ 126mg/dl, or blood sugar postprandial ≥200mg/dl and glycosylated hemoglobin above 6.5%. Obstructive sleep apnea risk was determined using the STOP-BANG questionnaire. Relationships between the risk of Obstructive sleep apnea and clinical variables along with its association with diabetic retinopathy were evaluated using bivariate analyses and covariate-adjusted logistic regression models.Results: A total of 150 diabetic patients were analyzed. Among them 30 (20.0%) patients had mild Obstructive sleep apnea, 14 (9.3%) patients had moderate Obstructive sleep apnea and 15 (10.0%) patients had severe sleep apnea. Among patients with diabetes mellitus on multivariate regression analysis Obstructive sleep apnea was associated with diabetes mellitus OR 2.05, 95% CI (1.69- 8.83) and diabetic retinopathy OR 1.20 (0.67-5.89).Conclusions: This study concludes that those individuals having diabetes may be suffering from obstructive sleep apnea and association with retinopathy these individuals can be considered for the screening of sleep-disordered breathing by polysomnography.

SLEEP-DISORDERED BREATHING IS PREDICTIVE FOR TYPE 2 DIABETES MELLITUS IN MINORITY AMERICANS

CHEST Journal ◽  
2008 ◽  
Vol 134 (4) ◽  
pp. 72P
Author(s):  
Kamran Mahmood ◽  
Natasha S. Akhter ◽  
Kamal Eldeirawi ◽  
Ergün Önal ◽  
John W. Christman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Sleep Disordered Breathing ◽  
Disordered Breathing

Large-Scale Cross-Sectional Study of the Problem Areas in Diabetes Survey among Japanese Patients with Type 2 Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2393-PUB
Author(s):  
KENICHIRO TAKAHASHI ◽  
MINORI SHINODA ◽  
RIKA SAKAMOTO ◽  
JUN SUZUKI ◽  
TADASHI YAMAKAWA ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Large Scale ◽  
Japanese Patients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetes Survey

scholarly journals Treatment patterns, persistence and adherence rates in patients with type 2 diabetes mellitus in Japan: a claims-based cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. e025806 ◽  
Author(s):  
Rimei Nishimura ◽  
Haruka Kato ◽  
Koichi Kisanuki ◽  
Akinori Oh ◽  
Shinzo Hiroi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Drug Class ◽  
Japanese Patients ◽  
Medical Data ◽  
Treatment Patterns ◽  
Administrative Claims ◽  
Antidiabetic Drug

ObjectiveTo determine real-world trends in antidiabetic drug use, and persistence and adherence, in Japanese patients with type 2 diabetes mellitus (T2DM).DesignRetrospective evaluation of administrative claims data (2011–2015) using the Japan Medical Data Center (JMDC) and Medical Data Vision (MDV) databases.SettingAnalysis of two administrative claims databases for Japanese patients with T2DM.ParticipantsAdults (aged ≥18 years) with an International Classification of Diseases, 10th Revision code of T2DM and at least one antidiabetic drug prescription.Main outcome measuresTreatment patterns in untreated (UT) or previously treated (PT) patients receiving antidiabetic therapy; persistence with treatment at 12 months; adherence to treatment at 12 months.Results40 908 and 90 421 patients were included from the JMDC and MDV databases, respectively. The most frequently prescribed therapy at the index (first prescription) date was dipeptidyl peptidase-4 inhibitor (DPP-4i) in UT patients (JMDC: 44.0%, MDV: 54.8%) and combination therapy in PT patients (74.6%, 81.1%). Most common combinations were DPP-4i plus: biguanide (BG; 11.4%, 10.9%), sulfonylurea (SU; 8.4%, 11.0%) or BG+SU (7.8%, 9.1%). In UT or PT patients from either database whose index prescription was for any antidiabetic drug class(es) other than DPP-4i, the most frequent add-on or switch was to DPP-4i. 12-month persistence with index monotherapy was highest with DPP-4i and BG. Adherence was high (≥80%) for all monotherapy schedules, except insulin and glucagon-like peptide-1 agonist, and for the five most frequent two-drug and three-drug combinations. Persistence was greater in elderly UT patients and in those receiving ≤5 medications, but comparatively worse in UT patients with ≥3 index antidiabetic drug classes.ConclusionsThe findings indicate that DPP-4i is the most commonly used antidiabetic drug class in Japanese patients with T2DM, and persistence and adherence to this antidiabetic drug class are high.

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