scholarly journals Reduced Brown Adipose Tissue Thermogenesis and Metabolic Rate in Pre-Obese Mice Treated with Monosodium-L-Glutamate.

1991 ◽  
Vol 38 (1) ◽  
pp. 75-79 ◽  
Author(s):  
KEIJI YOSHIOKA ◽  
TOSHIHIDE YOSHIDA ◽  
MOTOHARU KONDO
Keyword(s):  
Adipose Tissue ◽  
Metabolic Rate ◽  
Brown Adipose Tissue ◽  
Obese Mice ◽  
Brown Adipose ◽  
Brown Adipose Tissue Thermogenesis

scholarly journals Caffeine activates brown adipose tissue thermogenesis and metabolic rate in mice.

1990 ◽  
Vol 36 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Keiji YOSHIOKA ◽  
Toshihide YOSHIDA ◽  
Kohkichi KAMANARU ◽  
Noriya HIRAOKA ◽  
Motoharu KONDO
Keyword(s):  
Adipose Tissue ◽  
Metabolic Rate ◽  
Brown Adipose Tissue ◽  
Brown Adipose ◽  
Brown Adipose Tissue Thermogenesis

scholarly journals Pyruvate induces torpor in obese mice

2018 ◽  
Vol 115 (4) ◽  
pp. 810-815 ◽  
Author(s):  
Marion Soto ◽  
Lucie Orliaguet ◽  
Michelle L. Reyzer ◽  
M. Lisa Manier ◽  
Richard M. Caprioli ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Body Temperature ◽  
Metabolic Rate ◽  
Brown Adipose Tissue ◽  
Mass Spectroscopy ◽  
Uncoupling Protein ◽  
Obese Mice ◽  
Uncoupling Protein 1 ◽  
Metabolic Intermediate ◽  
Brown Adipose

Mice subjected to cold or caloric deprivation can reduce body temperature and metabolic rate and enter a state of torpor. Here we show that administration of pyruvate, an energy-rich metabolic intermediate, can induce torpor in mice with diet-induced or genetic obesity. This is associated with marked hypothermia, decreased activity, and decreased metabolic rate. The drop in body temperature correlates with the degree of obesity and is blunted by housing mice at thermoneutrality. Induction of torpor by pyruvate in obese mice relies on adenosine signaling and is accompanied by changes in brain levels of hexose bisphosphate and GABA as detected by mass spectroscopy-based imaging. Pyruvate does not induce torpor in lean mice but results in the activation of brown adipose tissue (BAT) with an increase in the level of uncoupling protein-1 (UCP1). Denervation of BAT in lean mice blocks this increase in UCP1 and allows the pyruvate-induced torpor phenotype. Thus, pyruvate administration induces torpor in obese mice by pathways involving adenosine and GABA signaling and a failure of normal activation of BAT.

Brown adipose tissue thermogenesis in women with polycystic ovary syndrome

2017 ◽  
Author(s):  
Soulmaz Shorakae ◽  
Eveline Jona ◽  
Courten Barbora de ◽  
Gavin Lambert ◽  
Elisabeth Lambert ◽  
...  
Keyword(s):  
Adipose Tissue ◽  
Polycystic Ovary Syndrome ◽  
Brown Adipose Tissue ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Brown Adipose ◽  
Brown Adipose Tissue Thermogenesis

W1854 Roux-en-Y Gastric Bypass Activates Brown Adipose Tissue and Increases Energy Expenditure in Obese Mice

2010 ◽  
Vol 138 (5) ◽  
pp. S-754 ◽  
Author(s):  
Nicholas Stylopoulos ◽  
Xiao B. Zhang ◽  
Anna-Liisa Brownell ◽  
Lee M. Kaplan
Keyword(s):  
Gastric Bypass ◽  
Adipose Tissue ◽  
Energy Expenditure ◽  
Brown Adipose Tissue ◽  
Obese Mice ◽  
Brown Adipose
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