19.1 Smart Biomaterials

2016 ◽  
Author(s):  
Karin Benz ◽  
Christoph Gaissmaier
Keyword(s):  
Smart Biomaterials

Importance of crosslinking strategies in designing smart biomaterials for bone tissue engineering: A systematic review

2019 ◽  
Vol 96 ◽  
pp. 941-954 ◽  
Author(s):  
Gopal Shankar Krishnakumar ◽  
Sowndarya Sampath ◽  
Shalini Muthusamy ◽  
Mary Arlene John
Keyword(s):  
Systematic Review ◽  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Smart Biomaterials

scholarly journals Synthesis and click chemistry of a new class of biodegradable polylactide towards tunable thermo-responsive biomaterials

2015 ◽  
Vol 6 (8) ◽  
pp. 1275-1285 ◽  
Author(s):  
Quanxuan Zhang ◽  
Hong Ren ◽  
Gregory L. Baker
Keyword(s):  
Click Chemistry ◽  
New Class ◽  
Smart Biomaterials

A new class of clickable polylactide was prepared and resulted in novel smart biomaterials with tunable thermo-responsive propertyviaclick chemistry.

scholarly journals Recent advances on polydiacetylene-based smart materials for biomedical applications

2020 ◽  
Vol 4 (4) ◽  
pp. 1089-1104 ◽  
Author(s):  
Fang Fang ◽  
Fanling Meng ◽  
Liang Luo
Keyword(s):  
Mechanical Properties ◽  
Drug Delivery ◽  
Tissue Engineering ◽  
Smart Materials ◽  
Biomedical Applications ◽  
Recent Advances ◽  
Smart Biomaterials

This review summarized most recent advances of designing strategies of polydiacetylene-based smart biomaterials with unique colorimetric and mechanical properties, as well as their applications in biosensing, drug delivery, and tissue engineering.

scholarly journals Chemical unfolding of protein domains induces shape change in programmed protein hydrogels

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Luai R. Khoury ◽  
Ionel Popa
Keyword(s):  
Protein Unfolding ◽  
Shape Change ◽  
Fold Increase ◽  
Protein Mechanics ◽  
Protein Polymer ◽  
Wide Range ◽  
Biomechanical Response ◽  
Polymer Interactions ◽  
Smart Biomaterials ◽  
Protein Hydrogels

AbstractProgrammable behavior combined with tailored stiffness and tunable biomechanical response are key requirements for developing successful materials. However, these properties are still an elusive goal for protein-based biomaterials. Here, we use protein-polymer interactions to manipulate the stiffness of protein-based hydrogels made from bovine serum albumin (BSA) by using polyelectrolytes such as polyethyleneimine (PEI) and poly-L-lysine (PLL) at various concentrations. This approach confers protein-hydrogels with tunable wide-range stiffness, from ~10–64 kPa, without affecting the protein mechanics and nanostructure. We use the 6-fold increase in stiffness induced by PEI to program BSA hydrogels in various shapes. By utilizing the characteristic protein unfolding we can induce reversible shape-memory behavior of these composite materials using chemical denaturing solutions. The approach demonstrated here, based on protein engineering and polymer reinforcing, may enable the development and investigation of smart biomaterials and extend protein hydrogel capabilities beyond their conventional applications.

MATERIALS SCIENCE: Smart Biomaterials

Science ◽  
2004 ◽  
Vol 305 (5692) ◽  
pp. 1923-1924 ◽  
Author(s):  
D. G. Anderson
Keyword(s):  
Materials Science ◽  
Smart Biomaterials

scholarly journals 'Smart' biomaterials and osteoinductivity

2011 ◽  
Vol 7 (4) ◽  
pp. 1-1 ◽  
Author(s):  
Huipin Yuan ◽  
Hugo Fernandes ◽  
Pamela Habibovic ◽  
Jan de Boer ◽  
Ana M. C. Barradas ◽  
...  
Keyword(s):  
Smart Biomaterials
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