Prospects for the production of radioisotopes and radiobioconjugates for theranostics

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jarosław Choiński ◽  
Monika Łyczko
Keyword(s):  
Nuclear Medicine ◽  
Review Article ◽  
Biologically Active Compounds ◽  
Diagnostic Methods ◽  
Biologically Active ◽  
Physical Characterization ◽  
Diagnosis And Treatment ◽  
Active Compounds

Abstract The development of diagnostic methods in medicine as well as the progress in the synthesis of biologically active compounds allows the use of selected radioisotopes for the simultaneous diagnosis and treatment of diseases, especially cancerous ones, in patients. This approach is called theranostic. This review article includes chemical and physical characterization of chosen theranostic radioisotopes and their compounds that are or could be useful in nuclear medicine.

scholarly journals Characterization of biologically active compounds from different herbs: Influence of drying and extraction methods

2022 ◽  
Vol 99 (1) ◽  
pp. 100297
Author(s):  
Kraipat Cheenkachorn ◽  
Marttin Gundupalli Paulraj ◽  
Prapakorn Tantayotai ◽  
Vanarat Phakeenuya ◽  
Malinee Sriariyanun
Keyword(s):  
Extraction Methods ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Active Compounds

scholarly journals DNA-tethered Polymersome Clusters as Nanotheranostic Platform

2021 ◽  
Vol 75 (4) ◽  
pp. 296-299
Author(s):  
Claire E. Meyer ◽  
Cora-Ann Schoenenberger ◽  
Juan Liu ◽  
Ioana Craciun ◽  
Cornelia G. Palivan
Keyword(s):  
Dna Hybridization ◽  
Molecular Level ◽  
External Surface ◽  
Cluster Formation ◽  
Biologically Active Compounds ◽  
Biologically Active ◽  
Diagnosis And Treatment ◽  
Active Compounds ◽  
Complementary Dna ◽  
Dna Strands

Nanotheranostics combine the use of nanomaterials and biologically active compounds to achieve diagnosis and treatment at the same time. To date, severe limitations compromise the use of nanotheranostic systems as potent nanomaterials are often incompatible with potent biomolecules. Herein we emphasize how a novel type of polymersome clusters loaded with active molecules can be optimized to obtain an efficient nanotheranostic platform. Polymersomes loaded with enzymes and specific dyes, respectively and exposing complementary DNA strands at their external surface formed clusters by means of DNA hybridization. We describe factors at the molecular level and other conditions that need to be optimized at each step of the cluster formation to favor theranostic efficiency.

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