ElePhant: ein anatomisch-elektronisches Simulationssystem für die Evaluation computerassistierter Eingriffe und die chirurgische Ausbildung / ElePhant: an anatomic-electronic simulation system for the evaluation of computer assisted interventions and surgical education

2007 ◽  
Vol 52 (6) ◽  
pp. 375-382 ◽  
Author(s):  
Hendrik Möckel ◽  
Ronny Grunert ◽  
Antje Pößneck ◽  
Mathias Hofer ◽  
Mario Thalheim ◽  
...  
Keyword(s):  
Surgical Education ◽  
Simulation System ◽  
Computer Assisted ◽  
Chirurgische Ausbildung ◽  
Electronic Simulation

Structure of the metallurgically oriented modelling system TK-StripCam for simulation of hot strip manufacture and application in research and production practice

2004 ◽  
Vol 120 ◽  
pp. 801-808
Author(s):  
U. Lotter ◽  
H.-P. Schmitz ◽  
L. Zhang
Keyword(s):  
Mechanical Properties ◽  
Simulation System ◽  
Physical Models ◽  
Computer Assisted ◽  
Microstructural Parameters ◽  
Hot Strip ◽  
Production Practice ◽  
Prediction Of Mechanical Properties ◽  
The One ◽  
Kinetics Of

For the prediction of mechanical properties of hot strip from production conditions by metallurgically oriented computer assisted simulation it is necessary to model all the numerous metallurgical processes leading to the microstructure of the finished product. The relevant microstructural parameters, calculated in this way, finally are converted into mechanical properties by application of suitable algorithms. At ThyssenKrupp Stahl such a metallurgically oriented simulation system has been developed and established under the name TK-StripCam. It is based on empirical-physical models. It allows on the one hand to predict important mechanical properties with considerable precision from production parameters as rolling schedule, cooling conditions etc. On the other hand by means of the simulation system course and kinetics of each metallurgical process included may be studied. It is evident that in a steel plant such a powerful tool finds a great variety of applications extending from offline use as a tool for development of steels and processes to inline use in the rolling mill to control the mechanical properties during production. In this work details of the philosophy and structure of the simulation system and examples for its application are presented.

3-D organization of fibrinogen receptors using computer reconstruction and whole-mount microscopy

1988 ◽  
Vol 46 ◽  
pp. 30-31
Author(s):  
E. T. O'Toole ◽  
R. R. Hantgan ◽  
J. C. Lewis
Keyword(s):  
Whole Blood ◽  
Colloidal Gold ◽  
Blood Platelets ◽  
Cell Contact ◽  
Computer Assisted ◽  
Adherent Cells ◽  
Differential Centrifugation ◽  
Computer Reconstruction ◽  
Sds Page ◽  
Whole Mount

Thrombocytes (TC), the avian equivalent of blood platelets, support hemostasis by aggregating at sites of injury. Studies in our lab suggested that fibrinogen (fib) is a requisite cofactor for TC aggregation but operates by an undefined mechanism. To study the interaction of fib with TC and to identify fib receptors on cells, fib was purified from pigeon plasma, conjugated to colloidal gold and used both to facilitate aggregation and as a receptor probe. Described is the application of computer assisted reconstruction and stereo whole mount microscopy to visualize the 3-D organization of fib receptors at sites of cell contact in TC aggregates and on adherent cells.Pigeon TC were obtained from citrated whole blood by differential centrifugation, washed with Ca++ free Hank's balanced salts containing 0.3% EDTA (pH 6.5) and resuspended in Ca++ free Hank's. Pigeon fib was isolated by precipitation with PEG-1000 and the purity assessed by SDS-PAGE. Fib was conjugated to 25nm colloidal gold by vortexing and the conjugates used as the ligand to identify fib receptors.

Computer Assisted Image Reconstruction of Oligomer Structure

1976 ◽  
Vol 34 ◽  
pp. 472-473
Author(s):  
A.M. Jones ◽  
A. Max Fiskin
Keyword(s):  
Three Dimensional ◽  
Depth Of Field ◽  
Computer Assisted ◽  
Projection Data ◽  
Two Dimensional ◽  
Single Particles ◽  
Dimensional Reconstruction ◽  
Computer Assisted Image ◽  
The Fourier Transform ◽  
Space Approach

If the tilt of a specimen can be varied either by the strategy of observing identical particles orientated randomly or by use of a eucentric goniometer stage, three dimensional reconstruction procedures are available (l). If the specimens, such as small protein aggregates, lack periodicity, direct space methods compete favorably in ease of implementation with reconstruction by the Fourier (transform) space approach (2). Regardless of method, reconstruction is possible because useful specimen thicknesses are always much less than the depth of field in an electron microscope. Thus electron images record the amount of stain in columns of the object normal to the recording plates. For single particles, practical considerations dictate that the specimen be tilted precisely about a single axis. In so doing a reconstructed image is achieved serially from two-dimensional sections which in turn are generated by a series of back-to-front lines of projection data.

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