An easily reproducible and biomechanically standardized model to investigate bone healing in rats, using external fixation / Ein leicht reproduzierbares und biomechanisch standardisiertes Modell zur Untersuchung der Knochenheilung in der Ratte unter Verwendung eines Fixateur Externe

2007 ◽  
Vol 52 (6) ◽  
pp. 383-390 ◽  
Author(s):  
Katharina Kaspar ◽  
Hanna Schell ◽  
Daniel Toben ◽  
Georg Matziolis ◽  
Hermann J. Bail
2011 ◽  
Vol 24 (04) ◽  
pp. 289-293 ◽  
Author(s):  
P. Maitre ◽  
T. Cachon ◽  
C. Carozzo ◽  
D. Fau ◽  
J-. P. Genevois ◽  
...  

SummaryObjective: To report the successful use of recombinant human bone morphogenetic protein-2 (rhBMP-2) in the treatment of an ante-brachial non-union, secondary to gunshot fracture, stabilized with circular external fixation in a cat.Procedure: Following a diagnosis of a highly comminuted gunshot fracture of the distal right radius and ulna, the fracture was stabilized with a circular external fixation. A two-ring frame was placed in closed fashion.Results: The skin wound healed uneventfully by second intention in 21 days. Twenty-eight weeks after external fixation, bone healing was absent. 0.8mL of 0.2mg/mL of rhBMP-2 in two collagen sponges was placed in the bone defect. Eight weeks after rhBMP-2 implantation, an early bone healing response was noted on radiographic evaluation. Sixteen weeks after rhBMP-2 implantation, fracture union was achieved.Discussion: To the authors’ knowledge, 160 ±g is the lowest reported dose of rhBMP-2 that leads to bony union in a cat. However as an individual case study, this report can not be used as evidence that rhBMP-2 at this lower dose is appropriate for use in all cats. Further studies are needed to establish the minimum efficient dose of rhBMP-2 in cats.


2021 ◽  
pp. 155633162199633
Author(s):  
Sherif Galal ◽  
Jonggu Shin ◽  
Peter Principe ◽  
Rena Mehta ◽  
Nathan Khabyeh-Hasbani ◽  
...  

Introduction: Magnetic internal lengthening nails (MILNs) have been used for humeral lengthening to avoid complications associated with external fixation. Purpose/Questions: We compared the 1-year Disabilities of the Arm, Shoulder and Hand (DASH) score, adjacent joint range of motion (ROM), bone healing index (BHI), length achieved, distraction rate, and complications when lengthening the humerus using MILN vs using external fixation. Methods: We conducted a retrospective cohort study of 18 patients (22 humeri) from January 2001 to March 2020 divided into 2 groups, the MILN group (7 patients, 7 humeri) and the mono-lateral fixator group (11 patients, 15 humeri). Results: The MILN group showed larger improvement of DASH scores (average 26.8 and 8 for MILN and fixator groups, respectively), less loss of elbow ROM (average 5° and 7° for MILN and fixator groups, respectively), and shorter time to full recovery of elbow ROM (average 39 days and 122 days for MILN and fixator groups, respectively). In the MILN group, there was slower distraction rate (average 0.66 mm/day and 0.86 mm/day for MILN and fixator groups, respectively), less lengthening achieved (average 5.2 cm and 7 cm for MILN and fixator group, respectively), and a lower lengthening percentage (average 19% and 41% for MILN and fixator group, respectively). Bone healing index (BHI) of 0.94 and 0.99 months/cm for the MILN and the fixator groups were similar. Conclusion: Humeral lengthening using the MILN allowed for early full recovery of joint ROM with comparable functional and radiographic outcomes compared with using external fixators.


1990 ◽  
Vol &NA; (256) ◽  
pp. 260???273 ◽  
Author(s):  
HANNU T. ARO ◽  
PATRICK J. KELLY ◽  
DAVID G. LEWALLEN ◽  
EDMUND Y. S. CHAO

2020 ◽  
Vol 110 (3) ◽  
Author(s):  
Jeffrey C. Karr

A case presentation of an adolescent with tarsal navicular avascular necrosis is presented. External fixation with tarsal navicular diastasis is a simple, straightforward management option to allow osseous regrowth and bone healing. In this case, the external fixator was well tolerated and the patient demonstrated a quick return to function without pain or discomfort. The external fixation technique with tarsal navicular diastasis is an uncommon but effective means of reversing the tarsal navicular avascular process and avoiding an open technique such as arthrodesis.


1991 ◽  
Vol 73-B (5) ◽  
pp. 819-825 ◽  
Author(s):  
AL Wallace ◽  
ER Draper ◽  
RK Strachan ◽  
ID McCarthy ◽  
SP Hughes

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