scholarly journals History of disruptions in laboratory medicine: what have we learned from predictions?

2019 ◽  
Vol 57 (3) ◽  
pp. 308-311 ◽  
Author(s):  
Larry J. Kricka

Abstract Predictions about the future of laboratory medicine have had a mixed success, and in some instances they have been overambitious and incorrectly assessed the future impact of emerging technologies. Current predictions suggest a more highly automated and connected future for diagnostic testing. The central laboratory of the future may be dominated by more robotics and more connectivity in order to take advantage of the benefits of the Internet of Things and artificial intelligence (AI)-based systems (e.g. decision support software and imaging analytics). For point-of-care testing, mobile health (mHealth) may be in the ascendancy driven by healthcare initiatives from technology companies such as Amazon, Apple, Facebook, Google, IBM, Microsoft and Uber.

Author(s):  
Chin-Pin Yeo ◽  
Carol Hui-Chen Tan ◽  
Edward Jacob

Background Point-of-care-testing (POCT) of haemoglobin Alc (HbA1c) is popular due to its fast turnaround of results in the outpatient setting. The aim of this project was to evaluate the performance of a new HbA1c POCT analyser, the Bio-Rad in2it, and compare it with the Siemens DCA 2000, Bio-Rad Variant II and Roche Tina-quant HbA1c Gen 2 assay on the cobas c501. Methods Imprecision of the four methods were compared by computing total imprecision from within-run and between-run data. A total of 80 samples were also compared and analysed by Deming regression and Altman–Bland difference test. Results Study of total imprecision of the in2it at HBA1c levels of 6.0% and 10.4% produced a coefficient of variation (%CV) of 3.8% and 3.7%, respectively. These results were more favourable as compared with the DCA 2000 but did not match the low imprecision of the central laboratory methods, the Bio-Rad Variant II and the Roche cobas c501. Comparison between the in2it and the central laboratory analysers, Bio-Rad variant II and cobas c501, revealed positive bias of 12% and 10%, respectively, supported by corresponding Deming regression equation slopes of +1.18 and +1.14. Comparison between the DCA 2000 and the central laboratory analysers revealed a bias that became increasingly positive with rising HbA1c concentrations with Deming regression analysis also revealing proportional and constant differences. Conclusions The in2it is a suitable POCT analyser for HbA1c but its less than ideal precision performance and differences with the central laboratory analysers must be communicated to and noted by the users.


Intexto ◽  
2019 ◽  
pp. 139-165
Author(s):  
André Luiz Martins Lemos ◽  
Daniel Góis Rabêlo Marques ◽  
Elias Cunha Bitencourt

The article describes how the Brazilian media shows the Internet of Things. The corpus is composed of 165 texts of Folha de São Paulo published online between 2011 and 2016. A data scraping tool was developed to extract the texts, which were analyzed using Atlas.ti. As criterion of analysis, we sought to identify the most cited objects, the qualities attributed to them, as well as the most recurrent IoT definitions. We also observed the main themes found in the texts and the judgment implied by the articles. We conclude that IoT is defined by the connectivity between intelligent objects, linked to technical and economic issues and to the imaginary of the future. These objects work mostly in the residential, health and transportation areas. Privacy issues still do not dominate the discussions.


Crimen ◽  
2020 ◽  
Vol 11 (3) ◽  
pp. 255-271
Author(s):  
Sanja Milivojević ◽  
Elizabeth Radulski

The Internet of Things (IoT) is poised to revolutionise the way we live and communicate, and the manner in which we engage with our social and natural world. In the IoT, objects such as household items, vending machines and cars have the ability to sense and share data with other things, via wireless, Bluetooth, or Radio Frequency IDentification (RFID) technology. "Smart things" have the capability to control their performance, as well as our experiences and decisions. In this exploratory paper, we overview recent developments in the IoT technology, and their relevance for criminology. Our aim is to partially fill the gap in the literature, by flagging emerging issues criminologists and social scientists ought to engage with in the future. The focus is exclusively on the IoT while other advances, such as facial recognition technology, are only lightly touched upon. This paper, thus, serves as a starting point in the conversation, as we invite scholars to join us in forecasting-if not preventing-the unwanted consequences of the "future Internet".


Author(s):  
Copyeditor JTDE

TelSoc has held its first forum on the future of Australia’s National Broadband Network (NBN). Three papers from that forum are published in this issue. TelSoc is planning a second forum, discussing the user potential of the NBN, in October 2019. The historical reprint in this issue is also NBN-related about online learning. The technical papers in this issue concern architectural issues in the Internet of Things and cybersecurity. The Journal welcomes further contributions on telecommunications and the digital economy.        


Micromachines ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1464
Author(s):  
Florina Silvia Iliescu ◽  
Ana Maria Ionescu ◽  
Larisa Gogianu ◽  
Monica Simion ◽  
Violeta Dediu ◽  
...  

The deleterious effects of the coronavirus disease 2019 (COVID-19) pandemic urged the development of diagnostic tools to manage the spread of disease. Currently, the “gold standard” involves the use of quantitative real-time polymerase chain reaction (qRT-PCR) for SARS-CoV-2 detection. Even though it is sensitive, specific and applicable for large batches of samples, qRT-PCR is labour-intensive, time-consuming, requires trained personnel and is not available in remote settings. This review summarizes and compares the available strategies for COVID-19: serological testing, Point-of-Care Testing, nanotechnology-based approaches and biosensors. Last but not least, we address the advantages and limitations of these methods as well as perspectives in COVID-19 diagnostics. The effort is constantly focused on understanding the quickly changing landscape of available diagnostic testing of COVID-19 at the clinical levels and introducing reliable and rapid screening point of care testing. The last approach is key to aid the clinical decision-making process for infection control, enhancing an appropriate treatment strategy and prompt isolation of asymptomatic/mild cases. As a viable alternative, Point-of-Care Testing (POCT) is typically low-cost and user-friendly, hence harbouring tremendous potential for rapid COVID-19 diagnosis.


Author(s):  
Ali Osman Serdar Citak

The history of the development of the Internet of Things (IoT) covers the last twenty years. Despite the short of time, the concept and implementation of the Internet of Things have widely spread all over the world. The impetus of the dissemination of the concept has exponential speed. In the near future, billions of smart sensors and devices will interact with one another without human intervention. The early impact of the Internet of Things has been observed and discussed in the areas of technology, transportation, production, and marketing. The prospective effect of the Internet of Things on the finance sector has been discussed recently. In this study, the development of the concept of the Internet of Things and it is effect on the finance sector and specifically the insurance and banking sectors and future expectations have been evaluated.


2021 ◽  
Author(s):  
Vinay Kishnani ◽  
Ankur Gupta

Over the last few years, the microfluidics phenomenon coupled with the Internet of Things (IoT) using innovative nano-functional materials have been recognized as one of the sustainable and economical tools for point of care testing (POCT) of various pathogens influencing the human health. The sensors based on these phenomena are aimed to be designed for their cost-effectiveness, to make it handy, environment-friendly and to get an accurate, easy, and rapid response. Considering the burgeoning importance of analytical devices in the healthcare domain, this review paper is based on the gist of sensing aspects of the micro fabricated paper-based analytical devices (μPADs). The article discusses not only the various used design methodologies and fabrication approaches, but also elucidates the recently reported surface modification strategies, detection mechanisms viz., colorimetric, electrochemical, fluorescence, electrochemiluminescence etc., and sensing characteristics of μPADs along with reported works equipped with the IoT platform for digital readout. In a nutshell, this article summarizes the state-of-the-art research work carried out over the nano functionalized paper-based analytical devices and associated challenges/solutions in the point of care testing domain.


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