Endothelial and metabolic disorders in adolescence: low birth weight is not an isolated risk factor

AbstractLow birth weight (LBW) seems to be a determining factor for many cardiovascular diseases in adult life.The objectives of this study were to investigate the occurrence of metabolic syndrome (MetS) and endothelial dysfunction in adolescents with LBW and compare them with subjects with normal birth weights (NBW).This retrospective cohort study evaluated 172 adolescents (86 in each group) aged 10–20 years, who were born in a reference maternity hospital. The following criteria were adopted: International Diabetes Federation parameters for the diagnosis of MetS and flow-mediated brachial artery dilatation for endothelial dysfunction. Student’s t-test or Mann-Whitney tests were used for continuous variables (depending on the normality of distribution evaluated by the Shapiro-Wilk test), and the Fisher exact test was used for categorical variables. The significance level was determined at 0.05.MetS was present in three cases of LBW and in four cases of NBW (p=0.70). The number of components of the syndrome was, on average, 0.6 and 0.5 in LBW and NBW, respectively (p=0.77). Endothelial dysfunction occurred in 25 (29.1%) cases of LBW and in 31 (36.1%) cases of NBW (p=0.33).LBW did not represent a risk factor in the occurrence of MetS or endothelial dysfunction in adolescence.

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Low birth weight: a possible risk factor also for liver diseases in adult life?

Medical Hypotheses ◽

10.1016/s0306-9877(03)00190-7 ◽

2003 ◽

Vol 61 (4) ◽

pp. 435-438 ◽

Cited By ~ 8

Author(s):

M.M Donma ◽

O Donma

Keyword(s):

Risk Factor ◽

Birth Weight ◽

Low Birth Weight ◽

Liver Diseases ◽

Adult Life

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RISK FACTORS ON STUNTING AMONG CHILDREN AGE 2-5 YEARS OLD IN BIROMARU OF CENTER PUBLIC HEALTH

Ghidza Jurnal Gizi dan Kesehatan ◽

10.22487/ghidza.v2i1.10369 ◽

2018 ◽

Vol 2 (1) ◽

pp. 39

Author(s):

Imelda Imelda ◽

Nurdin Rahman ◽

Rosmala Nur

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Birth Weight ◽

Low Birth Weight ◽

Control Sample ◽

Iodized Salt ◽

Practice Pattern ◽

Feeding Practice ◽

Significance Level ◽

Iodine Test

Background & Objective: Stunted is a condition of disruption of growth in children caused by chronic malnutrition. Prevalence of stunting in Sigi regency is 45,20% (2015) and stunting incidence in Puskesmas Biromaru for children aged 2-5 are 60 cases (2017). This study aims to determine the risk factors of stunting events in children aged 2-5 years. Materials and Methods: Types of analytical survey research with Case Control design. Sampling method with total sampling and purposive sampling control sample based on certain consideration with ratio 1: 2, with case sample in this research as many as 60 children and control samples as much as 120, each sample is chosen based on age as matching. Stunting degree expressed by z-score height by age. Complete basic immunization data, feeding practice patterns, low birth weight and iodized salt obtained through interviews using a questionnaire and iodine test. The analysis used is the odd ratio with a significance level of 95%. Results: Complete basic immunization of OR 7,667 (95% CI 3,753-15,662), practice pattern of feeding OR 30,565 (95% CI 9.043-103,314), low birth weight OR 6,956 (95% CI 4,446-14,104) and iodized salt OR 8,632 (95% CI 4,268-17,456) is a risk factor for stunting events and has a significant relationship. Conclusion: Practice pattern of feeding is a major risk factor for stunting with OR 30,565

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Low Birth Weight and Schizophrenia

The British Journal of Psychiatry ◽

10.1192/bjp.165.3.357 ◽

1994 ◽

Vol 165 (3) ◽

pp. 357-362 ◽

Cited By ~ 72

Author(s):

Larry Rifkin ◽

Shôn Lewis ◽

Peter Jones ◽

Brian Toone ◽

Robin Murray

Keyword(s):

Risk Factor ◽

Birth Weight ◽

Cognitive Function ◽

Low Birth Weight ◽

Adult Life ◽

Affective Psychosis ◽

Foetal Growth ◽

Premorbid Adjustment ◽

Schizophrenic Patients ◽

Neurodevelopmental Impairment

BackgroundLow birth weight has been postulated to be a risk factor for schizophrenia.MethodObstetric history, premorbid adjustment, and cognitive function during admission were assessed in 167 patients with DSM–III schizophrenia or affective psychosis.ResultsA birth weight of less than 2500 g was significantly more common in patients with schizophrenia than in those with affective psychosis. Schizophrenic patients as a group had significantly lower mean birth weight, a finding which was particularly marked after controlling for sociodemographic confounders. In schizophrenic men, lower birth weight was highly significantly correlated with poorer premorbid social and cognitive ability, and with impairment of adult cognitive function.ConclusionsNeurodevelopmental impairment may cause poor foetal growth, and schizophrenia in adult life.

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