Low Birth Weight and Schizophrenia

1994 ◽  
Vol 165 (3) ◽  
pp. 357-362 ◽  
Author(s):  
Larry Rifkin ◽  
Shôn Lewis ◽  
Peter Jones ◽  
Brian Toone ◽  
Robin Murray
Keyword(s):  
Risk Factor ◽  
Birth Weight ◽  
Cognitive Function ◽  
Low Birth Weight ◽  
Adult Life ◽  
Affective Psychosis ◽  
Foetal Growth ◽  
Premorbid Adjustment ◽  
Schizophrenic Patients ◽  
Neurodevelopmental Impairment

BackgroundLow birth weight has been postulated to be a risk factor for schizophrenia.MethodObstetric history, premorbid adjustment, and cognitive function during admission were assessed in 167 patients with DSM–III schizophrenia or affective psychosis.ResultsA birth weight of less than 2500 g was significantly more common in patients with schizophrenia than in those with affective psychosis. Schizophrenic patients as a group had significantly lower mean birth weight, a finding which was particularly marked after controlling for sociodemographic confounders. In schizophrenic men, lower birth weight was highly significantly correlated with poorer premorbid social and cognitive ability, and with impairment of adult cognitive function.ConclusionsNeurodevelopmental impairment may cause poor foetal growth, and schizophrenia in adult life.

Endothelial and metabolic disorders in adolescence: low birth weight is not an isolated risk factor

2014 ◽  
Vol 0 (0) ◽  
Author(s):  
Priscila de Jesus dos Santos Alves ◽  
Ana Ciléia P.T. Henriques ◽  
Livia R.M. Pinto ◽  
Rosa Maria S. Mota ◽  
Carlos Henrique M. Alencar ◽  
...  
Keyword(s):  
Risk Factor ◽  
Birth Weight ◽  
Endothelial Dysfunction ◽  
Low Birth Weight ◽  
Adult Life ◽  
International Diabetes Federation ◽  
Categorical Variables ◽  
Fisher Exact Test ◽  
Continuous Variables ◽  
Significance Level

AbstractLow birth weight (LBW) seems to be a determining factor for many cardiovascular diseases in adult life.The objectives of this study were to investigate the occurrence of metabolic syndrome (MetS) and endothelial dysfunction in adolescents with LBW and compare them with subjects with normal birth weights (NBW).This retrospective cohort study evaluated 172 adolescents (86 in each group) aged 10–20 years, who were born in a reference maternity hospital. The following criteria were adopted: International Diabetes Federation parameters for the diagnosis of MetS and flow-mediated brachial artery dilatation for endothelial dysfunction. Student’s t-test or Mann-Whitney tests were used for continuous variables (depending on the normality of distribution evaluated by the Shapiro-Wilk test), and the Fisher exact test was used for categorical variables. The significance level was determined at 0.05.MetS was present in three cases of LBW and in four cases of NBW (p=0.70). The number of components of the syndrome was, on average, 0.6 and 0.5 in LBW and NBW, respectively (p=0.77). Endothelial dysfunction occurred in 25 (29.1%) cases of LBW and in 31 (36.1%) cases of NBW (p=0.33).LBW did not represent a risk factor in the occurrence of MetS or endothelial dysfunction in adolescence.

Low birth weight. A risk factor for development of diabetic nephropathy?

Diabetes ◽  
1995 ◽  
Vol 44 (12) ◽  
pp. 1405-1407 ◽  
Author(s):  
P. Rossing ◽  
L. Tarnow ◽  
F. S. Nielsen ◽  
B. V. Hansen ◽  
B. M. Brenner ◽  
...  
Keyword(s):  
Risk Factor ◽  
Diabetic Nephropathy ◽  
Birth Weight ◽  
Low Birth Weight

Premature birth, low birth weight, small for gestational age and chronic non-communicable diseases in adult life: A systematic review with meta-analysis

2020 ◽  
Vol 149 ◽  
pp. 105154 ◽  
Author(s):  
Elaine Luiza Santos Soares de Mendonça ◽  
Mateus de Lima Macêna ◽  
Nassib Bezerra Bueno ◽  
Alane Cabral Menezes de Oliveira ◽  
Carolina Santos Mello
Keyword(s):  
Systematic Review ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Premature Birth ◽  
Meta Analysis ◽  
Adult Life ◽  
Communicable Diseases ◽  
Non Communicable Diseases

Risk Factor Analysis of Intraventricular Hemorrhage in Low-Birth-Weight Infants

1982 ◽  
Vol 37 (5) ◽  
pp. 331-333
Author(s):  
CHRISTINE E. CLARK ◽  
RONALD I. CLYMAN ◽  
ROBERT S. ROTH ◽  
SUSAN H. SNIDERMAN ◽  
BART LANE ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Risk Factor ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Intraventricular Hemorrhage ◽  
Risk Factor Analysis ◽  
Low Birth Weight Infants

Low birth weight as a risk factor for seizure following acute subdural hematoma

2009 ◽  
Vol 25 (9) ◽  
pp. 1101-1104
Author(s):  
Satoshi Kurabe ◽  
Takatoshi Sorimachi ◽  
Osamu Sasaki ◽  
Tetsuo Koike ◽  
Yukihiko Fujii
Keyword(s):  
Risk Factor ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Subdural Hematoma ◽  
Acute Subdural Hematoma

Contribution of periodontal disease in pregnant women as a risk factor for low birth weight

2009 ◽  
Vol 37 (6) ◽  
pp. 527-533 ◽  
Author(s):  
Simone S. Cruz ◽  
Maria da Concei����o N. Costa ◽  
Isaac S. Gomes-Filho ◽  
Edson J. C. Rezende ◽  
Maur��cio L. Barreto ◽  
...  
Keyword(s):  
Risk Factor ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Periodontal Disease ◽  
Pregnant Women

scholarly journals Effect of maternal anaemia on birth weight of term babies

2018 ◽  
Vol 5 (3) ◽  
pp. 1019
Author(s):  
Mohandas Nair ◽  
Gireesh S. ◽  
Rubeena Yakoob ◽  
Cheriyan N. C.
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Head Circumference ◽  
Adult Life ◽  
Anthropometric Measures ◽  
Maternal Anaemia ◽  
Medical College ◽  
Anemia During Pregnancy ◽  
The Difference ◽  
Long Term Impact

Background: Low birth weight is the major determinant of mortality, morbidity and disability in infancy and childhood and has a long-term impact on health outcome in adult life. The objectives of this study were to study the relationship between maternal anemia and birth weight of babies and to study anthropometric measures of babies born to anemic and non-anemic mothers and to correlate the timing of anemia with birth weight of babies.Methods: Term babies born in Institute of Maternal and Child Health, Government Medical College, Kozhikode from November 2014 to October 2016 fulfilling the criteria were divided into 2 groups, cases (term babies with birth weight <2500g) and controls (term babies with weight >2500g) and studied and their maternal hemoglobin values were compared.Results: Maternal anaemia in all three trimesters was found to be more in cases compared to controls. Mean 1st trimester hemoglobin of cases was 10.68 g/dl which was significantly lower when compared to controls. Mean 2nd trimester hemoglobin of cases was 10.36 g/dl compared to 11.47 g/dl in controls. Mean 3rd trimester hemoglobin of cases was 10.42 g/dl which was also significantly lower compared to 11.32 g/dl in controls. SGA babies were also found to be more in cases, 89%, compared to 18% in controls. The difference in head circumference between two groups was not statistically significant. Mean length of babies were higher in controls compared to cases. Mothers with anemia at any time during pregnancy was found to have 4.3 times higher risk of giving birth to low birth weight babies compared to non-anemic mothersConclusion: Anemia during pregnancy is a risk factor for low birth weight and SGA, independent of the trimester. Length of babies born to anaemic mothers is also low. But it does not have a significant effect on head circumference of babies.

scholarly journals Predictive Validity of the Bayley-III Cognitive Scores at 6 Months for Cognitive Outcomes at 24 Months in Very-Low-Birth-Weight Infants

2021 ◽  
Vol 9 ◽  
Author(s):  
Tzu-Yu Liu ◽  
Jui-Hsing Chang ◽  
Chun-Chih Peng ◽  
Chyong-Hsin Hsu ◽  
Wai-Tim Jim ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Birth Weight ◽  
Cognitive Function ◽  
Low Birth Weight ◽  
Predictive Validity ◽  
Predictive Value ◽  
Very Low Birth Weight ◽  
Muscle Tone ◽  
Cognitive Outcomes ◽  
Cognitive Score

Purpose: To assess the predictive validity of the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) cognitive scores at 6 months of corrected age (CA) for cognitive outcomes at 24 months of CA in very-low-birth-weight (VLBW) infants and investigate the predictors of change in cognitive outcomes.Methods: We retrospectively evaluated VLBW children enrolled in the Taiwan Premature Infant Follow-up Network between 2010 and 2015 and completed the Bayley-III at CA of 6 and 24 months. The predictive validity of the cognitive performance at 6-month CA for the cognitive outcomes at 24-month CA was analyzed. The positive and negative predictive factors were also evaluated using logistic regression. Cut-off scores of &lt;70 and &lt;85 were used to identify lower functioning groups based on the Bayley-III definition.Results: A total of 2,972 VLBW children, born with a mean weight of 1116.4 ± 257.5 g and mean gestational age of 29.0 ± 2.8 weeks, were evaluated. A cognitive score of &lt;70 at 6-month CA had a positive predictive value (PPV) of 27.4% (95% confidence interval [CI]: 19.2–35.7%) for a cognitive score of &lt;70 at 24-month CA, while the negative predictive value (NPV) was 97.3% (95% CI: 96.7–97.9%). A cut-off score of 85 had a PPV of 33.6% (95% CI: 28.1–39.0%) and an NPV of 87.7% (95% CI: 86.4–88.9%). Abnormal muscle tone at 6 months was a risk factor for cognitive function decline at 24 months for both Bayley-III cognitive cut-off scores: scores of 70 (adjusted odds ratio [AOR]: 2.8; 95% CI: 1.5–5.5) and 85 (AOR: 2.6; 95% CI: 1.6–4.1). Lower maternal socioeconomic status was associated with a worsening of the cognitive function in infants at 24 months who scored ≥85 at 6 months (AOR: 1.6; 95% CI: 1.2–2.0).Conclusion: Subnormal Bayley-III cognitive scores at 6-month CA were not predictive of subnormal cognitive function at 24-month CA. In children with normal cognition during early infancy, abnormal muscle tone and lower maternal socioeconomic status may influence the cognitive developing process; this highlighted the importance of early identification of high risk infants and complete preterm infant-associated public health policies to promote an improved neurodevelopmental outcome.

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