Coexistence of dyschondrosteosis associated to SHOX deficiency, pseudohypoparathyroidism 1B, and chronic autoimmune thyroiditis: a case report

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Fernando Marin ◽  
Esteban Jodar ◽  
Jaime Sánchez del Pozo
Keyword(s):  
Case Report ◽  
Parathyroid Hormone ◽  
Hashimoto’S Thyroiditis ◽  
Unusual Case ◽  
Clinical Symptoms ◽  
Large Deletion ◽  
Hashimoto's Thyroiditis ◽  
Chronic Autoimmune Thyroiditis ◽  
Methylation Alteration ◽  
Biochemical Abnormalities

AbstractWe present an unusual case of SHOX deficiency associated with Léri-Weill dyschondrosteosis (LWD), Hashimoto’s thyroiditis and pseudohypoparathyroidism 1B in a young woman. To our knowledge, this is the first ever report of these disorders coexisting. At the age of nine years, the proband was diagnosed of hypothyroidism due to Hashimoto’s thyroiditis, and developed biochemical abnormalities consistent with hyperphosphatemia, mild hypocalcemia and elevated parathyroid hormone without any clinical symptoms except short stature. Replacement therapy with levothyroxine, calcium and alphacalcidol was initiated. The diagnosis of pseudohypoparathyroidism 1B was confirmed at the age of 17.5 years with the demonstration of methylation alteration at the GNAS locus. At the age of 16 years, 3.5 years after her menarche, she presented clear features of LWD. A large deletion of the SHOX gene was confirmed. Family genetic tests were not doable since she was adopted. We discuss the diagnostic challenges of these coexisting rare endocrinopathies.

scholarly journals Case Report: Familial Hypocalciuric Hypercalcaemia and Hashimoto's Thyroiditis

2020 ◽  
Vol 7 ◽  
Author(s):  
Shahd Mobarak ◽  
Munir Tarazi ◽  
Harry Spiers ◽  
Anjali Santhakumar ◽  
Bence Forgacs
Keyword(s):  
Case Report ◽  
Hashimoto’S Thyroiditis ◽  
Hashimoto's Thyroiditis

scholarly journals Hürthle Cell Adenoma in a Hashimoto's Thyroiditis Patient: A Rare Case Report

2021 ◽  
Vol 4 (3) ◽  
Author(s):  
Ramesh Mahadev Tambat ◽  
Sreenivas M. D. ◽  
Tejas A. P. ◽  
Nitin Kumar K ◽  
Sadiq Nawaz F ◽  
...  
Keyword(s):  
Case Report ◽  
Hashimoto’S Thyroiditis ◽  
Rare Case ◽  
Hashimoto's Thyroiditis ◽  
Cell Adenoma ◽  
Hürthle Cell ◽  
Rare Case Report

scholarly journals Aerobic physical exercise and prolactin levels in blood during breastfeeding in woman with Hashimoto’s thyroiditis: A case report

2020 ◽  
Vol 77 (2) ◽  
pp. 225-228
Author(s):  
Ksenija Bubnjevic ◽  
Dusan Ugarkovic ◽  
Jelena Kovacevic
Keyword(s):  
Case Report ◽  
Physical Exercise ◽  
Aerobic Exercise ◽  
Hashimoto’S Thyroiditis ◽  
Negative Impact ◽  
Prolactin Secretion ◽  
World Health ◽  
Moderate Intensity ◽  
Hashimoto's Thyroiditis ◽  
Singleton Pregnancy

Introduction. The World Health Organization (WHO) exclusively recommends breastfeeding for the first six months of the newborn life. Many factors affect milk production. Physical exercise can significantly affect prolactin secretion in the blood. Case report. A respondent in this study was a primipara (33 years old) diagnosed with Hashimoto's thyroiditis and a singleton pregnancy. During pregnancy and after the childbirth, she continued with light to moderate physical exercise. During the first six months after the childbirth, the light to moderate intensity aerobic exercise had no negative impact on the blood level of prolactin and growth and development of the child. Conclusion. In this case study, light to moderate intensity aerobic exercise had no negative impact on the level of prolactin in the blood during the first six months after the childbirth in a woman with Hashimoto's thyroiditis.

scholarly journals Hyperthyroid Phase of Hashimoto's Thyroiditis

2019 ◽  
Vol 26 (1) ◽  
pp. 123
Author(s):  
Siti Nurul Hapsari ◽  
Sidarti Soehita
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Benign Lesion ◽  
Peripheral Blood Smear ◽  
Liver Function Tests ◽  
Hashimoto Thyroiditis ◽  
Ca 125 ◽  
Hashimoto's Thyroiditis ◽  
Thyroid Function Tests ◽  
Chronic Autoimmune Thyroiditis ◽  
Function Tests

Hashimoto thyroiditis (chronic autoimmune thyroiditis) is the most common cause of hypothyroidism in iodine-sufficient areas of the world. This condition, however, can sometimes show hyperthyroidism. A 39-year-old femalewas admitted to hospital due to shortness of breath and tremor four hours before hospitalization. There were nausea, chestpain, cold chills, and palpitation. She was diagnosed with Hashimoto's thyroiditis and routinely received tyrosol,propranolol, and dexamethasone. Physical examination showed cervical mass, afebrile, blood pressure of 130/70 mmHg,pulse rate of 110 beats/minute and respiratory rate of 20 breaths/minute. Laboratory examinations showed WBC 7.53 x 109/L, Hb 11.0 g/dL and platelet count of 168 x 109/L. Chest X-Ray: negative for infiltrates. Several laboratory testswere performed, abnormal results were as follows: FT4 level of 2.96 ng/dL (increased), TSH level of 0.003 µIU/mL(decreased), anti-TPO (antithyroid microsomal antibody) level of 306 IU/ml (increased), and IgE level of 213.6 IU/mL(increased). Peripheral blood smear, coagulation test, serum electrolytes, liver function tests, renal function tests, urinalysis,CEA and Ca 125 were within normal limits. Thyroid ultrasound was performed and showed a benign lesion. Fine needleaspiration biopsy showed lymphocytic Hashimoto's thyroiditis. Echocardiography showed hyperthyroid heart disease. Dueto an increase of anti-TPO and FT4 levels, a decrease of TSH levels and lymphocytic thyroiditis from FNAB, this patient wasdiagnosed with a hyperthyroid phase of Hashimoto's thyroiditis. Thyroid function tests and thyroid antibody tests must bemonitored to distinguish between the hyperthyroid and hypothyroid phase of Hashimoto thyroiditis.

Association of Hashimoto’s Thyroiditis and Burkitt Lymphoma: A Rare Condition to Be Considered

Praxis ◽  
2021 ◽  
Vol 110 (14) ◽  
pp. 812-815
Author(s):  
Dea Degabriel ◽  
Alberto Cerutti ◽  
Laura Caramanica ◽  
Alessandro Viganò ◽  
and Tanja Fusi-Schmidhauser
Keyword(s):  
Weight Loss ◽  
Case Report ◽  
Hashimoto’S Thyroiditis ◽  
Rare Condition ◽  
Hashimoto's Thyroiditis ◽  
Low Grade ◽  
Thyroid Lymphoma ◽  
Thyroid Mass ◽  
Primary Thyroid Lymphoma ◽  
Rule Out

Abstract. We present the case of a 72-year-old woman who was diagnosed with Hashimoto’s thyroiditis and who developed a low-grade fever, fatigue, and weight loss that prompted to perform a thyroid biopsy to rule out an underlying primary thyroid lymphoma. This case report offers the opportunity to review the association between Hashimoto’s thyroiditis and primary thyroid lymphoma. Furthermore, it underlines the importance of considering the diagnosis of lymphoma when a thyroid mass is found in patients with an underlying Hashimoto’s disease, as the timely management is essential for survival with this rare thyroid condition.

scholarly journals Severe unilateral orbitopathy in a patient with Hashimoto’s thyroiditis - a case report

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ewa Cyranska-Chyrek ◽  
Michal Olejarz ◽  
Ewelina Szczepanek-Parulska ◽  
Piotr Stajgis ◽  
Anna Pioch ◽  
...  
Keyword(s):  
Case Report ◽  
Hashimoto’S Thyroiditis ◽  
Hashimoto's Thyroiditis

Onset of Autoimmune Hepatitis During Intravenous Steroid Therapy for Thyroid-Associated Ophthalmopathy in a Patient with Hashimoto's Thyroiditis: Case Report

Thyroid ◽  
2004 ◽  
Vol 14 (8) ◽  
pp. 631-634 ◽  
Author(s):  
Mario Salvi ◽  
Guia Vannucchi ◽  
Francesco Sbrozzi ◽  
Alessandra Bottari Del Castello ◽  
Alessandra Carnevali ◽  
...  
Keyword(s):  
Case Report ◽  
Autoimmune Hepatitis ◽  
Steroid Therapy ◽  
Hashimoto’S Thyroiditis ◽  
Hashimoto's Thyroiditis ◽  
Intravenous Steroid ◽  
Thyroid Associated Ophthalmopathy
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