scholarly journals Red cell mass and blood volume in low birth weight infants

1978 ◽  
Vol 6 (4) ◽  
pp. 213-219 ◽  
Author(s):  
R. O. Robinson ◽  
P. M. Emerson ◽  
D. Howes ◽  
M. Fujimura ◽  
P. Howat ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Blood Volume ◽  
Cell Mass ◽  
Red Cell ◽  
Low Birth Weight Infants ◽  
Red Cell Mass

scholarly journals Early vs. Late Red Cell Transfusion in Low Birth Weight Infants 986

1998 ◽  
Vol 43 ◽  
pp. 170-170 ◽  
Author(s):  
Robert J Connelly ◽  
Sharon H Stone ◽  
Robin K Whyte
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Red Cell ◽  
Low Birth Weight Infants ◽  
Red Cell Transfusion

Circulating blood volumes in pulmonary hypertension associated with erythrocytosis – the effects of therapeutic hemodilution

2003 ◽  
Vol 13 (6) ◽  
pp. 544-550 ◽  
Author(s):  
Rilvani C. Gonçalves ◽  
Carlos Alberto Buschpigell ◽  
Antonio Augusto Lopes
Keyword(s):  
Pulmonary Hypertension ◽  
Blood Volume ◽  
Plasma Volume ◽  
Cell Mass ◽  
Red Cell ◽  
Total Blood Volume ◽  
Eisenmenger Syndrome ◽  
Total Blood ◽  
Red Cell Mass ◽  
Blood Volumes

In the Eisenmenger syndrome, indirect estimation of blood volumes may provide quite inaccurate information when seeking to define therapeutic strategies. With this in mind, we analyzed directly the red cell mass, plasma volume, and total blood volume in patients with pulmonary hypertension associated with congenital cardiac defects and erythrocytosis, comparing the results with the respective estimated volumes, and examining the changes induced by therapeutic hemodilution.Thus, we studied 17 patients with the Eisenmenger syndrome, aged from 15 to 53 years, in the basal condition, studying 12 of them both before and after hemodilution. We also investigated five individuals with minimal cardiac lesions, aged from 14 to 42 years, as controls. Red cell mass and plasma volumes were measured using [51 chromium]-sodium chromate and [131iodine]-albumin respectively. Hemodilution was planned so as to exchange 10% of the total blood volume, using 40,000 molecular weight dextran simultaneously to replace the removed volume. The mean values of the red cell mass, plasma volume and total blood volume as assessed by radionuclide techniques were 32%, 31% and 32% higher than the respective volumes as estimated using empirical mathematical formulas (p < 0.002). The measured total blood volume was also 19% higher in the patients compared with controls. Following a period of 5 days after hemodilution, we noted a 13% reduction in red cell mass (p = 0.046), and 10% reduction in total blood volume (p = 0.02), albeit with no changes in the plasma volume.We conclude that direct measurement of blood volumes is useful for proper management of these patients, and provides results that are considerably different from those obtained by empirical estimations.

Blood distribution during cardiac arrest induced by hypothermia

1961 ◽  
Vol 16 (3) ◽  
pp. 538-540
Author(s):  
Paul W. Willard ◽  
Steven M. Horvath
Keyword(s):  
Cardiac Arrest ◽  
Body Temperature ◽  
Blood Volume ◽  
Cell Mass ◽  
The Body ◽  
Whole Body ◽  
Red Cell ◽  
Red Cell Mass ◽  
Blood Redistribution ◽  
Blood Volumes

Blood volumes with simultaneous blood- and red cell-distribution measurements were determined by the Cr51 technique in four groups of rats. In splenectomized and nonsplenectomized animals, blood volume of the whole body, lung, spleen, liver, kidney, heart, diaphragm, and gastrocnemius muscle was measured in both the control rats (body temperature 37 C) and in rats with hypothermically induced cardiac arrest (body temperature 8–9 C). Splenectomy caused alterations in some visceral blood volumes without concurrent changes in red cell mass. With cardiac arrest increased quantities of blood and red cell mass were observed in the lung, liver, and gastrocnemius in both splenectomized and nonsplenectomized groups. In the nonsplenectomized animals an increase of over 100 % in spleen blood volume was observed. When the two hypothermic groups were compared, differences existed only in blood volume of the lung, heart, and kidney. Hypothermia induced a pattern of blood redistribution toward visceral areas of the body. Submitted on October 14, 1960

PLASMA VOLUME STUDIES IN LOW BIRTH WEIGHT INFANTS

PEDIATRICS ◽  
1966 ◽  
Vol 38 (6) ◽  
pp. 1020-1027
Author(s):  
George Cassady
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Blood Volume ◽  
Plasma Volume ◽  
Gestational Age ◽  
Growth Retardation ◽  
Low Birth Weight Infants ◽  
Uterine Growth ◽  
Degree Of Maturity ◽  
Intra Uterine Growth Retardation

An average plasma volume of 46.8 ± 7.1 ml/kg and blood volume of 87.9 ± 13.6 ml/kg was found in 69 true premature infants studied during the first 12 hours of life. Respiratory distress syndrome in these infants was not associated with an altered plasma or blood volume. However, the degree of maturity, estimated by either birth weight or gestational age, was found to be inversely related to the plasma volume. Intra-uterine growth retardation, defined on the basis of disproportionately low birth weight in relation to gestational age, was associated with an elevated average plasma volume (52.0 ± 7.8 ml/kg) during the 4 hours after birth. Despite rapid adjustment of this volume to normal between 4 and 12 hours of age, the average blood volume in this group of infants was significantly elevated (102.0 ± 18.7 ml/kg). These studies reveal direct, objective and measurable differences between growth-retarded and true premature low birth weight infants and represent an attempt toward more accurate definition and understanding of intra-uterine growth retardation.

Acute hypervolemia, cardiac performance, and aerobic power during exercise

1982 ◽  
Vol 52 (5) ◽  
pp. 1186-1191 ◽  
Author(s):  
I. L. Kanstrup ◽  
B. Ekblom
Keyword(s):  
Blood Volume ◽  
Aerobic Power ◽  
Cell Mass ◽  
Hemoglobin Concentration ◽  
Cardiac Performance ◽  
Red Cell ◽  
Vo2 Max ◽  
Plasma Volume Expansion ◽  
Arterial Blood ◽  
Red Cell Mass

The relative importance of blood volume (BV) for the maximum aerobic power (VO2 max) was evaluated in healthy subjects by sequential measurements without intervention under two conditions: 1) after hemodilution with a plasma expander, thus increasing BV but keeping red cell mass constant and lowering hemoglobin concentration [Hb], and 2) after whole blood withdrawal, which restored BV to control conditions but reduced red cell mass and [Hb] to equal conditions under 1. After BV expansion (avg 700 ml), we found an unchanged VO2 max compared with control data despite lowered [Hb]. Cardiac output (Q) was increased after BV expansion at rest and during all exercise levels (maximum 27.4 and 29.5 l . min-1, respectively). Peak stroke volume was increased from 144 to 173 ml. Arterial blood pressures were either unchanged or lowered. In contrast, after blood letting to a similar [Hb], we found a significantly reduced VO2 max. These findings indicate a significant influence of the size of the blood volume on cardiac performance. The increased Qmax is discussed in relation to preload, inotropic state, heart rate, and afterload. Plasma volume expansion causes increased preload which may explain this primary effect on the central circulation (Frank-Starling effect).

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