Therapeutic applications of selenium-derived compounds

2018 ◽  
Vol 38 (2) ◽  
pp. 49-76 ◽  
Author(s):  
Amna Kamal ◽  
Muhammad Adnan Iqbal ◽  
Haq Nawaz Bhatti
Keyword(s):  
Human Body ◽  
Biomedical Applications ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Biochemical Reactions ◽  
Therapeutic Applications ◽  
Minimal Toxicity ◽  
Structure Activity ◽  
Recent Developments

AbstractSelenium is a biocompatible element and participates in several biochemical reactions occurring in the human body. Its biocompatibility and minimal toxicity has attracted researchers to develop selenium-based drugs. Hence, recent developments on biomedical applications of selenium-based compounds have been discussed. A structure activity relationship has also been interpreted.

scholarly journals Research developments in the syntheses, anti-inflammatory activities and structure–activity relationships of pyrimidines

RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 6060-6098
Author(s):  
Haroon ur Rashid ◽  
Marco Antonio Utrera Martines ◽  
Adriana Pereira Duarte ◽  
Juliana Jorge ◽  
Shagufta Rasool ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Pyrimidine Derivatives ◽  
Structure Activity Relationships ◽  
Sar Studies ◽  
Structure Activity ◽  
Recent Developments ◽  
Anti Inflammatory

This review sums up recent developments in the syntheses, anti-inflammatory activities, and structure–activity relationship (SAR) studies of pyrimidine derivatives.

Recent developments on the structure–activity relationship studies of MAO inhibitors and their role in different neurological disorders

RSC Advances ◽  
2016 ◽  
Vol 6 (48) ◽  
pp. 42660-42683 ◽  
Author(s):  
Bhupinder Kumar ◽  
Sheetal Sheetal ◽  
Anil K. Mantha ◽  
Vinod Kumar
Keyword(s):  
Neurological Disorders ◽  
Structure Activity Relationship ◽  
Effective Drug ◽  
Activity Relationship ◽  
Mao Inhibitors ◽  
Drug Candidates ◽  
Structure Activity ◽  
Recent Developments

Development of MAO inhibitors as effective drug candidates for the management and/or treatment of different neurological disorders.

Recent developments on (−)-colchicine derivatives: Synthesis and structure-activity relationship

2020 ◽  
Vol 185 ◽  
pp. 111788
Author(s):  
Abdullah A. Ghawanmeh ◽  
Hussein M. Al-Bajalan ◽  
Mukram Mohamed Mackeen ◽  
Feras Q. Alali ◽  
Kwok Feng Chong
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Recent Developments ◽  
Colchicine Derivatives

ChemInform Abstract: Some Recent Developments in the Synthesis and Structure-Activity Relationship of Novel Taxanes

ChemInform ◽  
2010 ◽  
Vol 33 (25) ◽  
pp. no-no
Author(s):  
John F. Kadow ◽  
Thomas Alstadt ◽  
Shu-Hui Chen ◽  
Pierre Dextraze ◽  
Karen Du ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Recent Developments ◽  
Relationship Of

scholarly journals A Recent Overview of 1,2,3-Triazole-Containing Hybrids as Novel Antifungal Agents: Focusing on Synthesis, Mechanism of Action, and Structure-Activity Relationship (SAR)

2022 ◽  
Vol 2022 ◽  
pp. 1-50
Author(s):  
Mahrokh Marzi ◽  
Mojtaba Farjam ◽  
Zahra Kazeminejad ◽  
Abolfazl Shiroudi ◽  
Amin Kouhpayeh ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Heterocyclic Compounds ◽  
Antifungal Agents ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Synthesis Mechanism ◽  
Structure Activity ◽  
Antifungal Effects ◽  
Recent Developments ◽  
Membered Heterocycle

A pharmacophore system has been found as 1,2,3-triazole, a five-membered heterocycle ring with nitrogen heteroatoms. These heterocyclic compounds can be produced using azide-alkyne cycloaddition processes catalyzed by ruthenium or copper. The bioactive compounds demonstrated antitubercular, antibacterial, anti-inflammatory, anticancer, antioxidant, antiviral, and antidiabetic properties. This heterocycle molecule, in particular, with one or more 1,2,3-triazole cores has been found to have the most powerful antifungal effects. The goal of this review is to highlight recent developments in the synthesis and structure-activity relationship (SAR) investigation of this prospective fungicidal chemical. Also there have been explained drugs and mechanism of action of a triazole compound with antifungal activity. This review will be useful in a variety of fields, including medicinal chemistry, organic chemistry, mycology, and pharmacology.

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