Addition of some 6-amino-4-aryl-2(1H)-pyridones to phenylisocyanate and related reactions
Keyword(s):
X Ray
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AbstractThe Michael addition of enaminoesters to coumarins leads to the formation of the rearranged adduct 1 whose structure has been previously elucidated by X-ray crystallographic analysis. Now, N- and/or O-carbamoylation of the 6-amino-2-pyridone 1 by treatment with phenyl isocyanate in a molar ratio of 1:1 and 1:2 gave N-mono- (2a) or N,O-bis-(phenylcarbamoyl) (3) derivatives, respectively. Further transformations of the corresponding new 2-pyridone derivative 2a into the O-acetyl derivative 2b and the chromeno[3,4-c]pyridine 4 are reported as well.
1994 ◽
Vol 59
(12)
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pp. 2621-2631
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2004 ◽
Vol 59
(4)
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pp. 375-379
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2018 ◽
Vol 42
(6)
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pp. 297-299
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2018 ◽
Vol 42
(9)
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pp. 467-470
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