Hyphodontal, a New Antifungal Inhibitor of Reverse Transcriptases from Hyphodontia sp. (Corticiaceae, Basidiomycetes)
1994 ◽
Vol 49
(9-10)
◽
pp. 561-570
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Keyword(s):
Abstract In a search for inhibitors of RNA-directed DNA polymerases a new isolactarane sesquiterpenoid, hyphodontal (1), was isolated from fermentations of a Canadian Hyphodontia species. Its structure was elucidated by spectroscopic methods. Hyphodontal strongly inhibits the growth of several yeasts and is a non-competitive inhibitor of avian myeloblastosis virus (Ki 346 μᴍ) and Moloney murine leukemia virus (Ki 112 μᴍ) reverse transcriptases. In addition, cytotoxic and antifungal activities were observed.
1995 ◽
Vol 50
(1-2)
◽
pp. 1-10
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2010 ◽
Vol 74
(9)
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pp. 1925-1930
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1996 ◽
Vol 40
(10)
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pp. 2311-2317
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2003 ◽
Vol 77
(9)
◽
pp. 5275-5285
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1989 ◽
Vol 9
(2)
◽
pp. 469-476
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1998 ◽
Vol 75
(1)
◽
pp. 9-20
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2019 ◽
Vol 294
(48)
◽
pp. 18220-18231
◽
2020 ◽
Keyword(s):
1979 ◽
Vol 29
(3)
◽
pp. 899-906
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Keyword(s):