A Study on the Relationship between Body Composition and Menopause Rating Scale (MRS), The Menopause-specific Quality of Life Questionnaire (MENQOL) of Postmenopausal Women

Abstract Background Patients with lung cancer (LC) have a poor quality of life (QoL) and easily suffer from psychological diseases. Previous studies focused less on the relationship between genetic factors and QoL, depression, and anxiety status in LC patients. The current study is intended to explore the relationship between SNPs and haplotypes of ERCC1 and ERCC2 and the QoL, depression and anxiety status of patients with LC. Methods QoL, depression and anxiety status were assessed in 291 LC patients using the European Organization for Research and Treatment of Cancer (EORTC) Core Quality of Life Questionnaire (QLQ-C30), EORTC Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13), SDS and SAS. Nine tag SNPs of ERCC1 and ERCC2 were detected using an improved multiplex ligation detection reaction (iMLDR) technique. Haplotype analysis was conducted using the software Haploview 4.2. The association between SNPs or haplotypes and QoL or depression or anxiety in LC patients was analyzed by regression analysis. Results ERCC1 rs11615 was associated with emotional functioning (P = 0.027), and ERCC1 rs3212986 was associated with anxiety scores (P = 0.018). ERCC1 rs762562-rs3212986 haplotype was associated with cognitive function (P = 0.029), somatic function (P = 0.014) and dysphagia (OR = 3.32, P = 0.044). Patients with ERCC1 rs3212986-rs11615 AG haplotype had worse cognitive function (adjusted Beta = − 5.42) and somatic function (adjusted Beta = − 6.55) and had severer symptoms of loss of appetite (adjusted OR = 1.67) and dysphagia (adjusted OR = 4.43) (All adjusted P < 0.05). ERCC2 rs13181-rs3916874-rs238416 haplotype was associated with emotional functioning (P = 0.035), pain at other sites (OR 1.88, P = 0.014), chest pain (OR 0.42, P = 0.02), dysphagia (OR 2.82, P = 0.048), and anxiety status (OR 0.23, P = 0.009). Conclusion After adjustment for environmental factors, SNPs and haplotypes of ERCC1 and ERCC2 were associated with different domains of QoL, depression and anxiety in LC patients.

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Utilizing the Menopause Rating Scale questionnaire in electronic form for evaluating the quality of life in postmenopausal women

Kontakt ◽

10.1016/j.kontakt.2017.01.008 ◽

2017 ◽

Vol 19 (1) ◽

pp. e12-e16

Author(s):

Markéta Moravcová ◽

Jana Holá

Keyword(s):

Quality Of Life ◽

Postmenopausal Women ◽

Rating Scale ◽

Electronic Form ◽

Menopause Rating Scale

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Depressed mood and poor quality of life in male patients with chronic renal failure undergoing hemodialysis

Brazilian Journal of Psychiatry ◽

10.1590/s1516-44462010005000025 ◽

2010 ◽

Vol 32 (4) ◽

pp. 369-374 ◽

Cited By ~ 10

Author(s):

Thales Weber Garcia ◽

Joel Paulo Russomano Veiga ◽

Lucilia Domingues Casulari da Motta ◽

Flávio José Dutra de Moura ◽

Luiz Augusto Casulari

Keyword(s):

Quality Of Life ◽

Kidney Disease ◽

Negative Correlation ◽

Rating Scale ◽

Significant Negative Correlation ◽

Life Questionnaire ◽

Quality Of Life Questionnaire ◽

Male Patients ◽

Hamilton Rating Scale

OBJECTIVE: To assess mood and quality of life in male hemodialysis patients, and to correlate mood swings with the different domains of the quality of life questionnaire. METHOD: Forty-seven male patients undergoing regular hemodialysis for more than six months were included in the study. The Hamilton Rating Scale for Depression and the Kidney Disease Quality of Life Questionnaire, in a version translated into and adapted to Portuguese, were used. RESULTS: The patients' age was 39.4 ± 8.9 years (median ± SD). Depression was observed in 32 (68.1%) patients according to the Hamilton Rating Scale for Depression. A significant negative correlation was found between the results from the Hamilton Rating Scale for Depression and the following parameters of the specific dimensions of the Kidney Disease Quality of Life Questionnaire: list of symptoms and problems (rs = -0.399; p = 0.005), quality of social interaction (rs = -0.433; p = 0.002), and quality of sleep (rs = -0.585; p < 0.001). Among the generic domains, mood showed a significant negative correlation with general health (rs = -0.475; p < 0.001), emotional well-being (rs = -0.354; p = 0.015), social functioning and energy/fatigue (rs = -0.518; p < 0.001). The other parameters of the Kidney Disease Quality of Life Questionnaire did not show significant correlations with the Hamilton Rating Scale for Depression. CONCLUSION: Mood showed a negative correlation with the various scores of quality of life assessed by the Kidney Disease Quality of Life Questionnaire, suggesting a possible influence of mood on the quality of life of chronic renal patients undergoing hemodialysis.

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Correlations between Psychiatric Symptoms and Quality of Life in Patients with Psychological Disorders: Hospital-Based Retrospective Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph19020732 ◽

2022 ◽

Vol 19 (2) ◽

pp. 732

Author(s):

Pi-Yu Su ◽

Shu-Fen Kuo ◽

Min-Huey Chung

Keyword(s):

Quality Of Life ◽

Rating Scale ◽

Psychological Symptoms ◽

Linear Regression Analysis ◽

Psychological Disorders ◽

World Health ◽

Life Questionnaire ◽

World Health Organization Quality ◽

The Relationship

Little research has been conducted on the relationship between the five-item Brief Symptom Rating Scale (BSRS-5) and quality of life in patients with mood disorders. The purpose of this study was to investigate potential effects of psychological symptoms on quality of life in patients with psychological disorders. We recruited 124 patients with psychological disorders from a psychological teaching hospital in northern Taiwan. Data were obtained from medical records of all patients with a diagnosis of mood or adjustment disorder. We assessed psychological symptoms on the BSRS-5 and examined quality of life by using the Taiwanese version of the abbreviated World Health Organization Quality of Life Questionnaire (WHOQOL-BREF). We performed hierarchical linear regression analysis to explore the relationship between psychological symptoms and quality of life. The analysis revealed a significant correlation between the items on the BSRS-5 and WHOQOL and their correlations with the total scores on these assessments (p < 0.01 and p < 0.05). Our findings indicated that scores on the BSRS-5 can predict scores on quality of life. This suggests that psychometrically measured psychological symptoms constitute critical determinants of quality of life.

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