scholarly journals Prenatal Ethanol Exposure Disrupts Intraneocortical Circuitry, Cortical Gene Expression, and Behavior in a Mouse Model of FASD

2013 ◽  
Vol 33 (48) ◽  
pp. 18893-18905 ◽  
Author(s):  
H. El Shawa ◽  
C. W. Abbott ◽  
K. J. Huffman
Keyword(s):  
Gene Expression ◽  
Mouse Model ◽  
Ethanol Exposure ◽  
Prenatal Ethanol Exposure ◽  
And Behavior

A Mouse Model of Prenatal Ethanol Exposure Using a Voluntary Drinking Paradigm

2003 ◽  
Vol 27 (12) ◽  
pp. 2009-2016 ◽  
Author(s):  
Andrea M. Allan ◽  
Julie Chynoweth ◽  
Lani A. Tyler ◽  
Kevin K. Caldwell
Keyword(s):  
Mouse Model ◽  
Ethanol Exposure ◽  
Prenatal Ethanol Exposure

Effect of prenatal ethanol exposure on postnatal neural gene expression in the rat

1991 ◽  
Vol 12 (4) ◽  
pp. 293-298 ◽  
Author(s):  
Christian C. G. Naus ◽  
John F. Bechberger
Keyword(s):  
Gene Expression ◽  
Ethanol Exposure ◽  
Prenatal Ethanol Exposure

Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake

2020 ◽  
Vol 165 ◽  
pp. 107917 ◽  
Author(s):  
Aranza Wille-Bille ◽  
Fabio Bellia ◽  
Ana María Jiménez García ◽  
Roberto Sebastián Miranda-Morales ◽  
Claudio D'Addario ◽  
...  
Keyword(s):  
Gene Expression ◽  
Environmental Enrichment ◽  
Ethanol Exposure ◽  
Ethanol Intake ◽  
Early Exposure ◽  
Prenatal Ethanol Exposure

GABAa receptor density alterations revealed in a mouse model of early moderate prenatal ethanol exposure using [18F]AH114726

2020 ◽  
Vol 88-89 ◽  
pp. 44-51
Author(s):  
Van T. Nguyen ◽  
Rajiv Bhalla ◽  
Gary Cowin ◽  
Damion H.R. Stimson ◽  
Xin Song ◽  
...  
Keyword(s):  
Mouse Model ◽  
Gabaa Receptor ◽  
Ethanol Exposure ◽  
Receptor Density ◽  
Prenatal Ethanol Exposure

Reversal of cardiomyopathy resulting from prenatal exposure to ethanol

1984 ◽  
Vol 42 ◽  
pp. 716-717
Author(s):  
C. Uphoff ◽  
C. Nyquist-Battie
Keyword(s):  
Prenatal Exposure ◽  
Heart Development ◽  
Membrane Integrity ◽  
Ethanol Exposure ◽  
Prenatal Ethanol Exposure ◽  
Pathological Changes ◽  
Prenatally Exposed ◽  
Inner Mitochondrial Membrane ◽  
Fetal Alcohol ◽  
Newborn Mice

Fetal Alcohol Syndrone (FAS) is a syndrome with characteristic abnormalities resulting from prenatal exposure to ethanol. In many children with FAS syndrome gross pathological changes in the heart are seen with septal defects the most prevalent abnormality recorded. Few studies in animal models have been performed on the effects of ethanol on heart development. In our laboratory, it has been observed that prenatal ethanol exposure of Swiss albino mice results in abnormal cardiac muscle ultrastructure when mice were examined at birth and compared to pairfed and normal controls. Fig. 1 is an example of the changes that are seen in the ethanol-exposed animals. These changes include enlarged mitochondria with loss of inner mitochondrial membrane integrity and loss of myofibrils. Morphometric analysis substantiated the presence of these alterations from normal cardiac ultrastructure. The present work was undertaken to determine if the pathological changes seen in the newborn mice prenatally exposed to ethanol could be reversed with age and abstinence.

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