scholarly journals Biology, detection, and clinical implications of circulating tumor cells

2014 ◽  
Vol 7 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Simon A Joosse ◽  
Tobias M Gorges ◽  
Klaus Pantel
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Clinical Implications

scholarly journals Circulating Tumor Cells in Gastrointestinal Malignancies: Current Techniques and Clinical Implications

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Georg Lurje ◽  
Marc Schiesser ◽  
Andreas Claudius Hoffmann ◽  
Paul Magnus Schneider
Keyword(s):  
Colorectal Cancer ◽  
Clinical Outcome ◽  
Disease Progression ◽  
Cancer Patients ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Response To Therapy ◽  
Clinical Implications ◽  
Gastrointestinal Malignancies ◽  
Progression Of Disease

Since their introduction more than 50 years by Engell, circulating tumor cells (CTCs) have been evaluated in cancer patients and their detection has been correlated with clinical outcome, in esophageal, gastric, and colorectal cancer. With the availability of refined technologies, the identification of CTCs from peripheral blood is emerging as a useful tool for the detection of malignancy, monitoring disease progression, and measuring response to therapy. However, increasing evidence suggests a variety of factors to be responsible for disease progression. The analysis of a single CTC marker is therefore unlikely to accurately predict progression of disease with sufficient resolution and reproducibility. Here we discuss the current concept of CTCs, summarize the available techniques for their detection and characterization, and aim to provide a comprehensive update on the clinical implications of CTCs in gastrointestinal (GI) malignancies.

scholarly journals The Potential Clinical Implications of Circulating Tumor Cells and Circulating Tumor Microemboli in Gastric Cancer

2019 ◽  
Vol 24 (9) ◽  
Author(s):  
Emne A. Abdallah ◽  
Alexcia C. Braun ◽  
Bianca C.T.C.P. Flores ◽  
Laís Senda ◽  
Ana Cláudia Urvanegia ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Clinical Implications ◽  
Circulating Tumor Microemboli

Brain Cancer Spreads

2014 ◽  
Vol 6 (247) ◽  
pp. 247fs28-247fs28 ◽  
Author(s):  
Lara Perryman ◽  
Janine T. Erler
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Brain Cancer ◽  
Clinical Implications ◽  
The Brain

The discovery that ~20% of patients with brain cancer have circulating tumor cells breaks the dogma that these cells are confined to the brain and has important clinical implications (Müller et al., this issue).

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