scholarly journals Diabetic ketoacidosis in people on maintenance haemodialysis: case reports and review of literature

2020 ◽  
Vol 20 (2) ◽  
pp. 89-95
Author(s):  
Apexa Kuverji ◽  
Kath Higgins ◽  
James O Burton ◽  
Andrew H Frankel ◽  
Chee Kay Cheung
Keyword(s):  
Renal Function ◽  
Kidney Disease ◽  
Case Reports ◽  
Physiological State ◽  
Review Of Literature ◽  
End Stage Kidney Disease ◽  
Maintenance Haemodialysis ◽  
Comprehensive Literature Review ◽  
End Stage ◽  
Learning Points

The management of diabetes ketoacidosis (DKA) in people with normal renal function is well established. Although DKA is less common in people with end-stage kidney disease (ESKD), when it occurs, the management needs to be adapted to account for the different physiological state that these patients present with. This report presents two cases of DKA in people on maintenance haemodialysis for ESKD. Each case identifies learning points, when combined with a comprehensive literature review, generates key recommendations on the management of DKA in people on maintenance haemodialysis.

Chronic kidney disease, pregnancy and haemodialysis: Case reports from a single centre in Kenya and literature review

2021 ◽  
pp. 1753495X2098540
Author(s):  
Samuel K Kabinga ◽  
Jackline Otieno ◽  
John Ngige ◽  
Seth O Mcligeyo
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Reports ◽  
Tertiary Hospital ◽  
Reproductive Age ◽  
Review Of Literature ◽  
Single Centre ◽  
End Stage Kidney Disease ◽  
Women Of Reproductive Age ◽  
End Stage

Chronic kidney disease (CKD) and end stage kidney disease are prevalent even in women of reproductive age. These are known to reduce fertility and successful pregnancy. There are chances of conception even in advanced CKD, though laden with complications. We present two cases of women who conceived in advanced CKD and are on haemodialysis in a tertiary hospital in Kenya and review of literature.

scholarly journals Tocilizumab preserves renal function in rheumatoid arthritis with AA amyloidosis and end-stage kidney disease: Two case reports

2021 ◽  
Vol 95 (1) ◽  
pp. 54-61
Author(s):  
Makoto Fukuda ◽  
Naoki Sawa ◽  
Junichi Hoshino ◽  
Kenichi Ohashi ◽  
Miyazono Motoaki ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Renal Function ◽  
Kidney Disease ◽  
Case Reports ◽  
Aa Amyloidosis ◽  
End Stage Kidney Disease ◽  
End Stage

END-STAGE KIDNEY DISEASE AND REPLACEMENT OF RENAL FUNCTION

2010 ◽  
pp. 99-107
Author(s):  
Michael J. Field ◽  
David C. Harris ◽  
Carol A. Pollock
Keyword(s):  
Renal Function ◽  
Kidney Disease ◽  
End Stage Kidney Disease ◽  
End Stage

scholarly journals COVID-19 among patients with end-stage kidney disease on maintenance haemodialysis: single haemodialysis centre experience from Bangladesh

2020 ◽  
pp. 41-45
Author(s):  
Mohammad Mehfuz E Khoda ◽  
Muhammad Abdur Rahim ◽  
Ishrat Jahan Shimu ◽  
Md Golzar Hossain ◽  
Munmun Dev ◽  
...  
Keyword(s):  
Kidney Disease ◽  
General Hospital ◽  
Blood Group ◽  
Health Care Facilities ◽  
Care Hospital ◽  
Rt Pcr ◽  
End Stage Kidney Disease ◽  
Case Record ◽  
Maintenance Haemodialysis ◽  
End Stage

Background: Severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection emerged in Wuhan, China in December 2019 and rapidly became pandemic. Unfortunately, there is a lack of evidence about the optimal management of corona virus disease-2019 (COVID-19) and even less is available in patients on maintenance haemodialysis than general population. So, the purpose of this study was to identify the incidence of SARS-CoV-2 infection among end-stage kidney disease (ESKD) patients in a haemodialysis unit in tertiary care hospital of Bangladesh. Methods: A cross-sectional study was conducted at haemodialysis unit of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General Hospital, Dhaka, Bangladesh from April to August 2020. All patients, who were on maintenance haemodialysis, twice or thrice weekly, were screened by reverse transcriptase-polymerase chain reaction (RT-PCR) for SARS-CoV-2, irrespective of symptoms. All data were collected in case record forms and discharged/referred patients were followed-up over phone. Results: During the study period, a total of 133 patients (males 70, 52.6%) were on regular maintenance haemodialysis in the study center. Most patients were in 5th and 6th decades of life. Twenty-one (15.8%) patients tested positive for SARS-CoV-2 by RT-PCR with female (16, 76.2%) predominance. Eighteen (18/21, 85.7%) patients had symptoms suggestive of SARS-CoV-2 infection and rest three (3/21, 14.3%) patients were diagnosed during routine screening. Common presentations were fever (42.9%), cough (66.7%) and respiratory distress (66.7%) and most had multiple symptoms. Blood group A (38%) and O (38%) showed the higher incidence of SARS-CoV-2 infection than blood group B and AB with equal mortality rate among them. Most patients (16/ 21, 76.2%) infected by SARS-CoV-2 were referred to COVID-dedicated hospitals, five (5/21, 23.8%) were shifted to intensive care unit (ICU) of BIRDEM General Hospital. Outcome was poor; 17 (17/21, 89%) patients died in hospitals and four (4/21, 19%) patients became free of SARS-CoV-2 infection. Caregivers/relative of four patients acquired COVID-19 in course of disease. Conclusion: One-sixth of patients on maintenance haemodialysis acquired SARS-CoV-2 infection with nearly ninety percent fatality rates. Despite having risk factors for severe infection by SARS-CoV-2, dialysis patient must visit health care facilities. So, utmost care should be taken to reduce risk of COVID-19 among such vulnerable group of patients. Birdem Med J 2020; 10, COVID Supplement: 41-45

scholarly journals Renal histology in diabetic nephropathy predicts progression to end-stage kidney disease but not the rate of renal function decline

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Paraish S. Misra ◽  
Stephen G. Szeto ◽  
Adriana Krizova ◽  
Richard E. Gilbert ◽  
Darren A. Yuen
Keyword(s):  
Renal Function ◽  
Diabetic Nephropathy ◽  
Kidney Disease ◽  
End Stage Kidney Disease ◽  
Renal Function Decline ◽  
Renal Histology ◽  
End Stage

Causes of death in renal disease

ESC CardioMed ◽  
2018 ◽  
pp. 981-984
Author(s):  
Thomas F. Mueller ◽  
Valerie Luyckx
Keyword(s):  
Coronary Artery Disease ◽  
Renal Function ◽  
Coronary Artery ◽  
Sudden Cardiac Death ◽  
Kidney Disease ◽  
Renal Disease ◽  
Cardiac Death ◽  
End Stage Kidney Disease ◽  
Artery Disease ◽  
End Stage

Chronic kidney disease (CKD) encompasses a spectrum of diseases that are identified by a glomerular filtration rate below 90 mL/min/1.73m2 or the presence of proteinuria, or both of these, persisting for over 3 months. In population-based studies, mortality in patients with CKD is consistently several-fold higher than that in patients without CKD, and the risk increases as the severity of renal function worsens. Mortality risk is, not surprisingly, highest among those with end-stage kidney disease. In developed countries, patients with CKD and end-stage kidney disease do not die of renal disease, but die primarily of non-renal causes, the relative proportions of which change across the spectrum of renal function. In the early stages of CKD, malignancy tends to be the predominant case of death; however, as renal function worsens, the proportion of deaths related to cardiovascular disease increases. Coronary artery disease contributes to most cardiac deaths in those with milder CKD. The proportions of cardiac and overall deaths from heart failure and sudden cardiac death increase progressively as renal function declines. Sudden cardiac death is a major cause of death among patients with end-stage kidney disease. Multiple factors including underlying coronary artery disease, left ventricular hypertrophy, valvular heart disease, arrhythmias, volume and electrolyte abnormalities, uraemia, and inflammation all likely contribute to the increased risk of cardiovascular death. Much work is needed to understand the pathophysiology and develop strategies to prevent cardiovascular deaths especially in the CKD population.

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