Assessment of a semi-automated software program for the identification of vertebral fractures in children

2017 ◽  
Author(s):  
Fawaz Alqahtani ◽  
Fabrizio Messina ◽  
Elzene Kruger ◽  
Heerunpal Gill ◽  
Michael Ellis ◽  
...  
2019 ◽  
Vol 29 (12) ◽  
pp. 6780-6789 ◽  
Author(s):  
Fawaz F. Alqahtani ◽  
Fabrizio Messina ◽  
Amaka C. Offiah

2017 ◽  
Vol 72 (10) ◽  
pp. 904.e11-904.e20 ◽  
Author(s):  
F.F. Alqahtani ◽  
F. Messina ◽  
E. Kruger ◽  
H. Gill ◽  
M. Ellis ◽  
...  

2011 ◽  
Vol 27 (12) ◽  
pp. 1157-1162 ◽  
Author(s):  
Antonio E. Muñiz ◽  
Steven Liner

2014 ◽  
Vol 98 (2) ◽  
pp. 107-114 ◽  
Author(s):  
M. A. Erfani ◽  
B. Pourabbas ◽  
H. Nouraie ◽  
I. Vadiee ◽  
A. R. Vosoughi

2012 ◽  
Vol 30 (22) ◽  
pp. 2760-2767 ◽  
Author(s):  
Nathalie Alos ◽  
Ronald M. Grant ◽  
Timothy Ramsay ◽  
Jacqueline Halton ◽  
Elizabeth A. Cummings ◽  
...  

Purpose Vertebral fractures due to osteoporosis are a potential complication of childhood acute lymphoblastic leukemia (ALL). To date, the incidence of vertebral fractures during ALL treatment has not been reported. Patient and Methods We prospectively evaluated 155 children with ALL during the first 12 months of leukemia therapy. Lateral thoracolumbar spine radiographs were obtained at baseline and 12 months. Vertebral bodies were assessed for incident vertebral fractures using the Genant semiquantitative method, and relevant clinical indices such as spine bone mineral density (BMD), back pain, and the presence of vertebral fractures at baseline were analyzed for association with incident vertebral fractures. Results Of the 155 children, 25 (16%; 95% CI, 11% to 23%) had a total of 61 incident vertebral fractures, of which 32 (52%) were moderate or severe. Thirteen (52%) of the 25 children with incident vertebral fractures also had fractures at baseline. Vertebral fractures at baseline increased the odds of an incident fracture at 12 months by an odds ratio of 7.3 (95% CI, 2.3 to 23.1; P = .001). In addition, for every one standard deviation reduction in spine BMD Z-score at baseline, there was 1.8-fold increased odds of incident vertebral fracture at 12 months (95% CI, 1.2 to 2.7; P = .006). Conclusion Children with ALL have a high incidence of vertebral fractures after 12 months of chemotherapy, and the presence of vertebral fractures and reductions in spine BMD Z-scores at baseline are highly associated clinical features.


2017 ◽  
Vol 42 (9) ◽  
pp. 2369-2375 ◽  
Author(s):  
Naoki Takahashi ◽  
Motokazu Sugimoto ◽  
Sarah P. Psutka ◽  
Baiyu Chen ◽  
Michael R. Moynagh ◽  
...  

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