scholarly journals Vitamin D absorption: consequences of gastric bypass surgery

2011 ◽  
Vol 164 (5) ◽  
pp. 827-832 ◽  
Author(s):  
Edo Aarts ◽  
Lenneke van Groningen ◽  
Ronald Horst ◽  
Darryl Telting ◽  
Adriaan van Sorge ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Premenopausal Women ◽  
Individual Variability ◽  
Common Finding ◽  
Morbidly Obese ◽  
Vitamin D Levels ◽  
Laparoscopic Rygb

BackgroundSevere vitamin D deficiency is a common finding in morbid obesity, and the incidence increases markedly after RYGB. Normalization of vitamin D levels after RYGB is difficult to achieve because the degree of surgery-induced malabsorption is not known.ObjectiveTo develop a test that quantifies the changes in intestinal cholecalciferol absorption induced by Roux-en-Y gastric bypass (RYGB) surgery.MethodsAbsorption characteristics of cholecalciferol were studied in 14 morbidly obese, premenopausal women before and 4 weeks after laparoscopic RYGB. Serum cholecalciferol levels were measured at baseline and 1, 2, 3, and 14 days after a single oral dose of 50 000 IU solubilized cholecalciferol.ResultsPeak serum cholecalciferol levels were observed on day 1 in all patients. They were 26.6±3.7% lower after RYGB (P=0.02). Inter-individual variability was high.ConclusionPeak cholecalciferol levels are reduced by about 25% after RYGB. Further analysis suggested that the timing of sampling in the current study was not optimal. This might have caused an underestimation of the true decrease in cholecalciferol absorption induced by RYGB.

Prevalence of vitamin D depletion among morbidly obese patients seeking gastric bypass surgery

2005 ◽  
Vol 1 (3) ◽  
pp. 243
Author(s):  
Arthur M. Carlin ◽  
Ali M. Meslemani ◽  
Jeffrey A. Genaw ◽  
Shiri Levy ◽  
Arti Bhan ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Vitamin D Depletion

scholarly journals Denosumab-Induced Hypocalcemia after Billroth II Gastric Bypass Surgery

2020 ◽  
Vol 2020 ◽  
pp. 1-4 ◽  
Author(s):  
Abigail M. Schmucker ◽  
Dina E. Green ◽  
Philip M. Montemuro
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Calcium Supplementation ◽  
Gastric Bypass Surgery ◽  
Gastric Ulcers ◽  
Billroth Ii ◽  
Vitamin D Levels ◽  
History Of

Hypocalcemia is a known risk following bariatric surgery and can contribute to the development of osteoporosis. Osteoporosis is commonly treated with denosumab, though denosumab can exacerbate underlying abnormalities in calcium homeostasis. We present the case of a 59-year-old female with severe hypocalcemia who had been treated with denosumab for osteoporosis three months before and had Billroth II gastric bypass surgery 15 years before, for bariatric purposes. Intravenous calcium supplementation was used to correct the initial electrolyte abnormality, and the patient was able to maintain appropriate calcium levels on high doses of oral calcium before discharge. Denosumab-induced hypocalcemia has been previously reported in patients with predisposing conditions including chronic kidney disease, primary sclerosing cholangitis, Crohn’s disease, and a history of sleeve gastrectomy for marginal gastric ulcers. A few cases of hypocalcemia have been reported in patients with a history of bariatric surgery secondary to vitamin D deficiency, but this report is unique in demonstrating denosumab-induced hypocalcemia after bariatric surgery with normal vitamin D levels, suggesting a primary malabsorption of calcium. The risk of severe hypocalcemia should be considered before initiating denosumab to treat osteoporosis in patients with a history of bariatric surgery. If denosumab is initiated, serum calcium levels should be closely monitored, and patients should be educated about the importance of adherence to calcium supplementation.

scholarly journals Mechanical colon obstruction due to the alimentary limb after Roux-en-Y gastric bypass: a case report

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Caspar Joyce Peterson ◽  
Jennifer Klasen ◽  
Tarik Delko ◽  
Romano Schneider
Keyword(s):  
Gastric Bypass ◽  
Bowel Obstruction ◽  
Transverse Colon ◽  
Bypass Surgery ◽  
Revisional Surgery ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese ◽  
Tight Closure ◽  
Alimentary Limb ◽  
Colon Obstruction

Abstract Background Small bowel obstruction is a known and potentially lethal complication after gastric bypass surgery, in both the early and the late postoperative course. Colon or large bowel obstruction, on the other hand, seems to be rare after gastric bypass surgery and thus is not routinely considered. Case presentation We present the case of a 21-year old morbidly obese caucasian patient who underwent laparoscopic Roux-en-Y gastric bypass surgery and developed an early severe transverse colon obstruction due to compression of the transverse colon by the antecolic alimentary limb. Emergency revisional surgery showed a short and tense alimentary limb mesentery and possibly tight closure of Petersen’s space contributing to the compression. Through opening of Petersen’s space and mobilization of alimentary limb mesentery, decompression was achieved, and the patient fully recovered. Conclusions This is a rare case of colon obstruction caused by direct compression of the transverse colon by the antecolic alimentary limb. We propose that a combination of short tense alimentary limb mesentery and perhaps tight closure of Petersen’s space was responsible for the obstruction in this case. Surgeons and treating physicians need to be aware of such rare causes of early postoperative bowel obstruction and take these into consideration when evaluating patients.

Variation in Postoperative Analgesic Requirements in the Morbidly Obese Following Gastric Bypass Surgery

1982 ◽  
Vol 2 (1) ◽  
pp. 50-53 ◽  
Author(s):  
Richard Bennett ◽  
Randal Batenhorst ◽  
David A. Graves ◽  
Thomas S. Foster ◽  
Ward O. Griffen ◽  
...  
Keyword(s):  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese

Predictors of psychological symptoms in morbidly obese patients after gastric bypass surgery

2012 ◽  
Vol 8 (6) ◽  
pp. 770-776 ◽  
Author(s):  
Joaquin Ortega ◽  
Regina Fernandez-Canet ◽  
Sagrario Álvarez-Valdeita ◽  
Norberto Cassinello ◽  
Maria Jose Baguena-Puigcerver
Keyword(s):  
Gastric Bypass ◽  
Bypass Surgery ◽  
Psychological Symptoms ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese ◽  
Obese Patients

Long-Term Effects of Sleeve Gastrectomy and Roux-en-Y Gastric Bypass Surgery on Type 2 Diabetes Mellitus in Morbidly Obese Subjects

2012 ◽  
Vol 256 (6) ◽  
pp. 1023-1029 ◽  
Author(s):  
Amanda Jiménez ◽  
Roser Casamitjana ◽  
Lílliam Flores ◽  
Judith Viaplana ◽  
Ricard Corcelles ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gastric Bypass ◽  
Bypass Surgery ◽  
Gastric Bypass Surgery ◽  
Morbidly Obese ◽  
Long Term Effects ◽  
Obese Subjects

scholarly journals Anthropometric Measurements and Correlations to Glucometabolic and Cardiovascular Risk in Obese Patients Undergoing Gastric Bypass Surgery

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Erica Aldenbäck ◽  
Hans-Erik Johansson
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Gastric Bypass ◽  
Fasting Glucose ◽  
Gastric Bypass Surgery ◽  
Cost Effective ◽  
Morbidly Obese ◽  
Obese Patients ◽  
Inclusion Criteria ◽  
Sagittal Abdominal Diameter

Abdominal obesity is associated with hypertension, increased fasting glucose, HbA1c, and cholesterol. Body mass index (BMI) is frequently used to measure and define obesity and as inclusion criteria for bariatric surgery. Sagittal abdominal diameter (SAD) has been suggested to predict the amount of visceral fat, metabolic traits, and cardiometabolic risk superior to BMI. The aim was to test whether SAD has stronger correlations to glucometabolic traits compared to BMI. One hundred and fifty-five (108 women, 47 men) morbidly obese patients undergoing bariatric surgery were evaluated before (baseline), 6 and 12 months after Roux-en-Y gastric bypass (RYGBP). BMI was reduced from 43.7 kg/m2 (baseline) to 31.3 kg/m2 (12 months) and SAD from 32.6 to 23.2 cm (both p <0 .001 ). SAD correlated with CRP ( p = 0.04 ), fasting glucose ( p = 0.008 ), HbA1c ( p = 0.016 ), triglycerides ( p = 0.017 ), systolic blood pressure ( p = 0.032 ), and vitamin D ( p = 0.027 ). BMI correlated with CRP ( p = 0.006 ), triglycerides ( p = 0.016 ), vitamin D ( p = 0.002 ), and magnesium ( p = 0.037 ). Despite RYGBP surgery, vitamin D was significantly increased. Liver enzymes were significantly lowered after RYGBP and the change over time in SAD correlated with gamma-glutamyltransferase. SAD was superior to BMI to predict glucose disturbance and dyslipidemia implying increased use of SAD as it is cost effective and simple to perform in the clinic and could be of value when considering patients for bariatric surgery.

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