Urinary steroid profiling by gas chromatography-mass spectrometry (GC-MS) in Cushing's syndrome

2019 ◽  
Author(s):  
Fideline Bonnet-Serrano ◽  
Anna Vaczlavik ◽  
Guillaume Assie ◽  
Jerome Bertherat ◽  
Marie-Claude Menet
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Cushing’S Syndrome ◽  
Cushing's Syndrome ◽  
Gas Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Steroid Profiling ◽  
Urinary Steroid

Generation of urinary steroid profiles in patients with adrenal incidentaloma using gas chromatography–mass spectrometry

2016 ◽  
Vol 71 (7) ◽  
pp. 748-754 ◽  
Author(s):  
L. I. Velikanova ◽  
E. G. Strel’nikova ◽  
E. V. Obedkova ◽  
N. S. Krivokhizhina ◽  
Z. R. Shafigullina ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Adrenal Incidentaloma ◽  
Gas Chromatography Mass Spectrometry ◽  
Chromatography Mass Spectrometry ◽  
Steroid Profiles ◽  
Urinary Steroid

The diagnostical importance of steroid profiles of biological fluids of patients with Cushing’s syndrome

2015 ◽  
Vol 61 (4) ◽  
pp. 4-8 ◽  
Author(s):  
Z R Shafigullina ◽  
L I Velikanova ◽  
N V Vorohobina ◽  
A A Lisicyn ◽  
E A Kuhianidze ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Steroid Hormones ◽  
Diagnostic Criteria ◽  
Cushing’S Syndrome ◽  
Biological Fluids ◽  
Cushing's Syndrome ◽  
Gas Chromatography Mass Spectrometry ◽  
Adrenocortical Adenoma ◽  
Steroid Profiles

Steroid profiles of 49 patients having Cushing’s syndrome were investigated. Differential diagnostic criteria of Cushing’s syndrome with adrenocortical adenoma and adrenocarcinoma and features of steroid hormones metabolism were established by combination of classical tests and steroid profiles investigation using HPLC and gas chromatography - mass-spectrometry. The adrenocarcinoma was diagnosed for 22,4% of patients having Cushing’s syndrome and the main biochemical criteria were the increasing of 11-deoxycortisol in blood (>20 ng/ml), the excretion of 18-OH-corticosterone and metabolites of glucocorticoids and pregnenes, 8,2% of patients having Cushing’s syndrome had additionally increased androgens metabolites excretion.

Microwave-assisted derivatization: Application to steroid profiling by gas chromatography/mass spectrometry

2014 ◽  
Vol 960 ◽  
pp. 8-13 ◽  
Author(s):  
Gregori Casals ◽  
Josep Marcos ◽  
Oscar J. Pozo ◽  
José Alcaraz ◽  
María Jesús Martínez de Osaba ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Gas Chromatography Mass Spectrometry ◽  
Microwave Assisted ◽  
Chromatography Mass Spectrometry ◽  
Steroid Profiling
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