Hip fracture and the brown tumors as clinical manifestation of primary hyperparathyroidism in late reproductive age woman: Case report.

2020 ◽  
Author(s):  
Liubov Yanevskaya ◽  
Tatiana Karonova ◽  
Karina Pogosian ◽  
Daria Ryzhkova ◽  
Elena Grineva

2017 ◽  
Vol 8 (5-6) ◽  
pp. 379-380
Author(s):  
A. Gamboa ◽  
E. Duaso ◽  
P. Marimón ◽  
J. Miquel ◽  
J. Gisbert ◽  
...  


2020 ◽  
Vol 48 (10) ◽  
pp. 030006052096648
Author(s):  
Yu Wang ◽  
Jie Liu

Bone disease is an important complication of hyperparathyroidism. We herein report a rare case of severe bone disease caused by primary hyperparathyroidism. A 33-year-old man presented with pain and restricted mobility in his right upper limb and right hip due to a fall 3 days previously. X-ray examination showed a fracture of the proximal and distal humerus. Computed tomography examination showed a supracondylar fracture of the right humerus, a fracture of the right femoral neck, a fracture of the right sciatic branch, and multiple brown tumors. Ultrasonography showed a 3.5- × 1.6-cm hypoechoic mass below the left lobe of the thyroid. The patient was diagnosed with primary hyperparathyroidism based on increased serum calcium and parathormone concentrations, pathological fractures, and multiple brown tumors. He therefore underwent bilateral lower parathyroidectomy. Pathological examination revealed a parathyroid adenoma. The patient recovered well after surgery and was followed up for 6 months with no symptoms of hyperparathyroidism. This case report suggests that clinicians should be aware of the possibility of severe bone disease secondary to primary hyperparathyroidism. Active and early diagnosis and surgical treatment are important in such cases.



2015 ◽  
Vol 65 (10) ◽  
pp. 558-562
Author(s):  
Kenji Yorita ◽  
Takanori Ayabe ◽  
Eiichi Chosa ◽  
Noriko Uchino ◽  
Yasuhiro Nagatomo ◽  
...  






2020 ◽  
Vol 10 (3-4) ◽  
pp. 94-100
Author(s):  
Zeina Hadad ◽  
Louise Tjelum ◽  
Pia Eiken ◽  
Waldemar Trolle ◽  
Ilia Haupter ◽  
...  


1970 ◽  
Vol 6 (2) ◽  
pp. 65-72
Author(s):  
Mariana Pires de Sousa e Silva ◽  
Marília Pires de Sousa e Silva ◽  
Afonso Carlos da Silva

Introdução: A Arterite de Takayasu (AT) é uma vasculite crônica de médios e grandes vasos cuja etiologia é desconhecida. A incidência anual de AT, segundo estatísticas americanas, é de cerca de 2,6 casos por milhão de pessoas, acometendo principalmente mulheres jovens na idade reprodutiva. Essa doença possui sintomas característicos, como claudicação de membros, dor torácica, ausência de pulsos braquiais, sopro carotídeo e ausência de pressão arterial nos membros superiores. Síndromes neurológicas, como Acidente Vascular Cerebral (AVC) e Ataque Isquêmico Transitório (AIT) são apresentadas por aproximadamente 10 a 20% dos pacientes com AT. Relato de Caso: Relatou-se o caso de paciente do sexo feminino, de 42 anos, branca, que apesar de apresentar os sintomas de AT com 15 anos, como dor em região torácica e hipertensão arterial, foi diagnosticada com AT somente após 25 anos. A paciente foi admitida no Pronto Socorro do Hospital Escola de Itajubá com sintomas que sugeriam um AVC, confirmado com Tomografia computadorizada (TC) de crânio e, posteriormente, AngioTC cerebral e de artérias carótidas e vertebrais que, juntamente com os sinais clínicos observados, como pulsos radiais não palpáveis bilateralmente e sopro carotídeo diagnosticaram a AT. Discussão: A AT costuma apresentar intervalo entre início de sintomas e diagnóstico entre dois e onze anos e pode estar associada a várias manifestações características. O diagnóstico de AT tardio tendo o AVC como primeira manifestação clínica é raro. Conclusão: A importância de se conhecer a AT está no fato do diagnóstico, bem como tratamento precoce poderem evitar complicações ou retardar o seu aparecimento.Palavras-chave: Arterite de Takayasu, Acidente Vascular Cerebral, Diagnóstico.ABSTRACTIntroduction: The Takayasu arteritis (TA) is a chronic vasculitis of medium and large vessel, whose etiology is unknown. The annual incidence of TA, according to American statistics, is about 2.6 cases per one million people, mainly affects young women in reproductive age. This disease shows typical symptoms such as limb lameness, chest pain, and absence of brachial pulses, carotid bruit and no blood pressure in the upper limbs. Neurological syndromes, such as cerebral vascular accident (CVA) and transient ischemic attack (TIA) are presented in approximately 10-20% of patients with TA. Case Report: It is reported a case of a female patient, 42 years old, white who, despite having the symptoms of TA, as pain in the thoracic region and hypertension when she was 15 years old, was diagnosed with the disease only after 25 years of age. The patient was admitted to the Emergency Room of Itajubá Teaching Hospital with symptoms suggesting a stroke, which was confirmed by computed tomography (CT) and later brain and carotid and vertebral arteries CT angiography which, together with the observed clinical signs , as the intangible radial pulses bilaterally and carotid bruit, made it possible to diagnose TA. Discussion: The AT usually presents interval between the beginning of the symptoms and diagnosis between two and eleven years and it may be associated with multiple specifics manifestations. The late diagnosis of AT that has AVC, as a first clinical manifestation is rare. Conclusion: The importance of knowing the AT is in the fact that the diagnosis and early treatment can prevent complications or at least delay its appearance.Keywords: Takayasu’s Arteritis, Cerebrovascular Accidents, Diagnosis.



2021 ◽  
pp. 63-65
Author(s):  
Fehmida M Laxmidhar ◽  
Bhavin P. Vadodariya ◽  
Sanjiv Shah ◽  
Murtuza I Laxmidhar

Background: Brown tumours are expansile osteolytic lesions of bone, occurring in Hyperparathyroidism. Brown tumours occur most commonly in ribs, clavicle, long bones and pelvis and are uncommon in other facial bones except mandible. Other facial bones are rarely affected. Brown tumors are due to the direct effect of the parathyroid hormone. Brown tumors occur more with primary hyperparathyroidism than secondary. However, they are reported more in secondary hyperparathyroidism. In primary hyperparathyroidism, a parathyroid adenoma is a cause in 81% while other causes include hyperplasia in 15% and parathyroid carcinoma only in 4%. We present a case report of maxillary Brown tumor due to parathyroid carcinoma in an elderly male patient. Case Report: A 67-year-old male presented with right maxillary swelling increasing in size for the last few months associated with ipsilateral nasal block and right eye epiphora. The contrast CT scan of paranasal sinuses and neck revealed a large expansile right maxillary tumor aggressively eroding maxillary wall with extension into the orbital oor, ethmoid, sphenoid sinuses, nasal cavity, and oral cavity with the erosion of hard palate and soft tissue extension to subcutaneous Plane. A three cm sized soft tissue density lesion was also noted posterior to the right thyroid lobe in CT sections of the neck. Blood prole was normal except extremely high serum parathormone and calcium as well as mildly elevated serum creatinine (S. PTH 3437 pg./ml. S. Ca. 19 mg%. S. Creatinine 1.77mg%.) Ultrasonography of the abdomen also revealed calcication in the renal medulla. Right lower parathyroidectomy was done with the frozen section as well as the Intraoperative Rapid PTH assay. The PTH level was reduced by 90 percent of the original value. The nal histopathology was suggestive of parathyroid carcinoma. Summary: The patient was under regular surveillance, as the maxillary tumor was under remittance after the resection of parathyroid carcinoma. Parathyroid carcinoma is a very rare tumor and involvement of maxillary bone due to primary hyperparathyroidism due to parathyroid carcinoma is also uncommon.



2021 ◽  
Author(s):  
Anas M. Bardeesi ◽  
Ashwag Alqurashi ◽  
Sumaih Shinawi ◽  
Firas R. A. Shffah ◽  
Abdulrazag Ajlan ◽  
...  


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