scholarly journals Changes in plasma concentrations of arginine vasotocin after intrauterine injections of prostaglandin F-2  and acetylcholine at various times during the oviposition cycle of the domestic hen (Gallus domesticus)

Reproduction ◽  
1987 ◽  
Vol 80 (1) ◽  
pp. 143-150 ◽  
Author(s):  
K. Shimada ◽  
N. Saito ◽  
K. Itogawa ◽  
T. I. Koike
1975 ◽  
Vol 67 (1) ◽  
pp. 59-70 ◽  
Author(s):  
SUSAN C. WILSON ◽  
P. J. SHARP

SUMMARY Changes in plasma LH concentrations after i.m. injections of 0·5 mg progesterone/kg at various stages of the ovulatory cycle were measured by radioimmunoassay. Four types of response were observed. (1) When the steroid was injected between 4 h after and 12 h before an ovulation, LH levels started to rise after 15–45 min and reached peak values within 90–120 min. The mean maximal incremental change in the level of LH was 1·58 ± 0·10 (s.e.m.) ng/ml (n = 37). (2) In contrast, when progesterone was injected 12–8 h before ovulation, i.e. immediately before a spontaneous pre-ovulatory LH surge, the resulting mean maximal incremental change in LH level, 0·79 ± 0·12 ng/ml (n = 9), was significantly smaller (P < 0·001). (3) If progesterone was injected 8–4 h before ovulation, i.e. when pre-ovulatory LH levels were rising, they immediately started to rise more rapidly and reached peak values within 45 min. The maximal incremental change in the level of LH under these circumstances, 2·34 ± 0·20 ng/ml (n = 12), was significantly greater (P < 0·001 in both cases) than the changes observed in the responses 1 and 2 described above. (4) Levels of LH generally showed no incremental change in response to injections of progesterone given 4–0 h before ovulation, i.e. when pre-ovulatory LH levels were falling. It was concluded that the type of change in plasma LH levels induced by progesterone depended upon the stage of the ovulatory cycle at which the steroid was injected.


1986 ◽  
Vol 66 (3) ◽  
pp. 643-651 ◽  
Author(s):  
J. A. FITZGERALD ◽  
G. A. EVERETT ◽  
J. APGAR

The effect of low dietary Zn intake upon several plasma endocrine and metabolic profiles was examined during late gestation in the ewe. Thirty adult, primiparous Finncross ewes were fed a low Zn diet with (+Zn, n = 14) or without (0Zn, n = 16) supplemental Zn in the drinking water starting day 1 of pregnancy. Although the mean prepartum progesterone and prolactin concentrations were lower (P < 0.05 and P < 0.01, respectively) in 0Zn than in +Zn ewes, the peak prolactin concentrations in 0Zn ewes at lambing were similar to +Zn ewes. Both basal and thyrotropin-releasing-hormone (TRH)-induced prolactin release were less (P < 0.01) in 0Zn ewes 2 d postpartum. Plasma concentrations of 13, 14-dihydro-15-keto prostaglandin F2α (PGFM) of ewes sampled within 45 min post-lambing were lower (P < 0.05) in 0Zn ewes. There was no difference in cortisol concentrations within 45 min after lambing between 0Zn and + Zn ewes. Plasma protein concentrations in 0Zn ewes were higher (P < 0.01) than those in +Zn ewes during pregnancy. In summary, these data show that low Zn intake in the pregnant ewe affected several endocrine and metabolic plasma parameters associated with normal pregnancy and parturition. Key words: Zinc, parturition, dystocia, feed intake, ovine


2010 ◽  
Vol 468 (3) ◽  
pp. 334-338
Author(s):  
Noboru Saito ◽  
Mariko Fujii ◽  
Kanae Sugiura ◽  
Nicoletta Aste ◽  
Kiyoshi Shimada

1991 ◽  
Vol 69 (9) ◽  
pp. 1355-1359 ◽  
Author(s):  
P. Lijnen ◽  
J. Staessen ◽  
R. Fagard ◽  
A. Amery

The effect of inhibition of prostaglandin synthesis by indomethacin on active renin and on acid-activable inactive renin was studied in nine healthy, sodium-replete men, both at rest and exercise. These volunteers were investigated after pretreatment with placebo or indomethacin, 150 mg daily for 3 days. Indomethacin induced a decrease in active (p = 0.004), total (p < 0.001), and inactive (p = 0.02) renin at rest recumbent on average by 42, 19, and 8%, respectively, and at rest sitting on average by 45, 15, and 3%, respectively. Inhibition of prostaglandins with indomethacin reduced (p < 0.001) active and total renin at each level of work load but not (p = 0.32) inactive renin. However, the exercise-induced stimulation (p < 0.05) of active and total renin still occur during indomethacin. Indomethacin reduced (p < 0.001) at rest sitting and at maximal exercise the plasma concentrations of immunoreactive prostaglandins E2 by 50 and 54%, respectively, prostaglandin F2α by 36 and 39%, respectively, and 13,14-dihydro-15-keto-prostaglandin Fα by 38 and 60%, respectively. The urinary excretion of immunoreactive prostaglandin E2 and F2α was also reduced.Key words: indomethacin, prorenin, active renin, prostaglandins.


Sign in / Sign up

Export Citation Format

Share Document