Malignant Pericardial Effusion--An Uncommon Complication of Multiple Myeloma: Case Report

2005 ◽  
Vol 8 (2) ◽  
pp. 87 ◽  
Author(s):  
Louis E. Samuels ◽  
Philbert Y. Van ◽  
Douglas E Gladstone ◽  
Marian M. Haber

Multiple myeloma is a condition usually associated with lesions of the skeleton. However, under rare circumstances, the malignant plasma cells may infiltrate the pericardium, resulting in an effusion. If left untreated, the abnormal accumulation of pericardial fluid will result in cardiac tamponade, requiring drainage. The following report describes a multiple myeloma patient who developed secondary pericardial and pleural effusions, which were surgically drained via a pleuropericardial window.

2020 ◽  
Vol 26 (6) ◽  
pp. 1499-1500
Author(s):  
Hikmettullah Batgi ◽  
Mehmet Sinan Dal ◽  
Alparslan Merdin ◽  
Merih Kızıl Çakar ◽  
Tuğçe Nur Yiğenoğlu ◽  
...  

Introduction Multiple myeloma is a malignant neoplasm of plasma cells. Lenalidomide-dexamethasone treatment is a common treatment regimen used in refractory multiple myeloma. Case report We describe the case of a 58-year-old male multiple myeloma patient with a history of relapse after six months of autologous stem cell transplantation. The patient had nausea and bloody diarrhea developed during lenalidomide treatment. Management and outcome: Computed tomography showed diffuse marked edematous thickness in the wall of colonic, hepatic and splenic flexure, transverse colon, descending colon and sigmoid colon. Colonoscopic observation revealed highly granular, hyperemic and fragile mucosa. Colon biopsy was consistent with ischemic colitis. Lenalidomide treatment was discontinued. One month later, colon findings were detected as normalized through a colonoscopy. Discussion Risk of developing ischemic colitis should be kept in mind in patients receiving lenalidomide which should be discontinued in cases with severe bloody diarrhea of unknown origin.


2011 ◽  
Vol 40 (8) ◽  
pp. 513-518 ◽  
Author(s):  
S Ghosh ◽  
P Wadhwa ◽  
A Kumar ◽  
KM Pai ◽  
S Seshadri ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Iuliana Vaxman ◽  
John Eaton ◽  
Hee Eun Lee ◽  
Morie A. Gertz

Herein we present a patient that underwent a liver transplant due to primary biliary cholangitis (PBC) and after 9 years developed multiple myeloma. Following the cessation of mycophenolate mofetil and 2 weeks after lenalidomide treatment was started, the patient experienced acute cellular rejection. The patient recovered after treatment with corticosteroids, resumption of mycophenolate mofetil, and cessation of lenalidomide. Lenalidomide-associated allograft rejection has been reported in other organs. However, this is the first case report of liver rejection induced by lenalidomide.


Sign in / Sign up

Export Citation Format

Share Document