scholarly journals The Relationship between Mitral Valve Prolapse and Acute Rheumatic Fever in Pediatric Patients.

1992 ◽  
Vol 33 (5) ◽  
pp. 585-590 ◽  
Author(s):  
Serap UYSAL ◽  
Kemal BAYSAL ◽  
Ayse BALAT ◽  
Mikail Yüksel

General considerations 144Acute rheumatic fever 146Mitral stenosis: clinical features 150Mitral stenosis: investigations 152Mitral stenosis guidelines 156Mitral regurgitation 158Mitral regurgitation guidelines 161Mitral valve prolapse 162Aortic stenosis 164Management of aortic stenosis 168Aortic regurgitation 170Aortic regurgitation guidelines ...


Cardiology ◽  
1979 ◽  
Vol 64 (1) ◽  
pp. 48-57 ◽  
Author(s):  
Fulvío Pileggi ◽  
Paulo Roberto Camargo ◽  
Egas Armelin ◽  
Giovanni Bellotti ◽  
Protásio da Luz ◽  
...  

Circulation ◽  
1980 ◽  
Vol 62 (3) ◽  
pp. 582-587 ◽  
Author(s):  
R E Kavey ◽  
H M Sondheimer ◽  
M S Blackman

PLoS ONE ◽  
2021 ◽  
Vol 16 (11) ◽  
pp. e0259737
Author(s):  
Telêmaco Luis da Silva ◽  
Antonio Pazin-Filho ◽  
Minna M. D. Romano ◽  
Virgínia P. L. Ferriani ◽  
José A. Marin-Neto ◽  
...  

Background Rheumatic heart disease (RHD) complicating acute rheumatic fever (ARF) remains an important health problem in developing countries. No definitive diagnostic test for ARF exists and the role of Doppler echocardiography (DEC) for long-term prognostic evaluation following ARF is not well established. Objective To investigate the prognostic value of DEC in patients with ARF as a predictor of chronic valve dysfunction. Methods Prospectively enrolled patients with clinical ARF had a DEC performed soon after diagnosis and repeated at 1, 3, 6 and 12 months and thereafter at every 1–2 years. We defined chronic valve dysfunction by ≥ 3 of the following: increased valve thickening, commissure fusion, subvalvular thickening, reduced leaflet mobility, non-trivial mitral and/or aortic regurgitation. We performed univariate analysis and developed multivariate logistic regression models to identify variables that may influence evolution to RHD. p <0.05 was considered significant. Results We evaluated 70(57% men) patients, 10.8±5.6 years-old during the ARF episode and followed for 95±26 months. Chronic valve dysfunction was identified in 36(51.4%) which fulfilled criteria for RHD and 10(27.8%) of them died or underwent valve surgery. Univariate analysis showed that mitral valve thickening and presence of mitral regurgitation at baseline DEC, were associated with RHD(p<0.01). Multivariate logistic regression showed that only mitral valve thickness either as a continuous (Odds-Ratio:5.8;95%CI:1.7–19.7) or as a categorical variable (Odds-Ratio:4.04;95%CI:1.06–15.3) was an independent predictor of chronic valve dysfunction. Conclusions Mitral leaflets thickening documented at the time of diagnosis of ARF is a consistent prognostic marker for the subsequent evolution to RHD.


2001 ◽  
Vol 11 (3) ◽  
pp. 285-288 ◽  
Author(s):  
Bülent Oran ◽  
Emre Atabek ◽  
Sevim Karaaslan ◽  
Ýsmail Reisli ◽  
Fatih Gültekin ◽  
...  

We have investigated the relationship between oxygen free radicals and acute rheumatic fever with regard to diagnosis of the disease process. At the time of diagnosis, we measured the levels of reactive oxygen molecules in the plasma, this being a parameter for oxygen free radicals, and discovered the levels to be significantly higher when compared with those measured in a control group (P< 0.05). The levels measured in the plasma, however, were not statistically different among patients with and without carditis.We found a progressive decrease in the levels measured in the plasma when patients with acute rheumatic fever were tested on the 15th, 30th and 90th days subsequent to diagnosis. By the 90th day, levels measured in the plasma were still higher, but no longer significantly elevated, when compared with the control group. The present study is preliminary, but raises the possibility that measurement of oxygen free radicals in the plasma could be used as a laboratory test for active state of acute rheumatic fever. Further investigations will be needed, nonetheless, to determine the clinical application of this technique.


Circulation ◽  
1987 ◽  
Vol 75 (4) ◽  
pp. 756-767 ◽  
Author(s):  
R A Levine ◽  
M O Triulzi ◽  
P Harrigan ◽  
A E Weyman

Sign in / Sign up

Export Citation Format

Share Document