scholarly journals Physical Activities Decrease Fasting Blood Glucose Level in Diabetes Mellitus Type 2 Patients: Use of International Physical Activity Questionnaire (IPAQ) in Rural Area

2019 ◽  
Vol 51 (4) ◽  
pp. 201-205
Author(s):  
Mirasari Putri ◽  
Rd.Tiara Indah Persariningrat ◽  
Samsudin Surialaga ◽  
Mas rizky A. A. Syamsunarno
Epigenomics ◽  
2021 ◽  
Author(s):  
Marwa Matboli ◽  
Doaa Ibrahim ◽  
Amany H Hasanin ◽  
Mohamed Kamel Hassan ◽  
Eman K Habib ◽  
...  

Aim: To assess isorhamnetin efficacy for diabetic kidney disease in a Type 2 diabetes mellitus rat model, through investigating its effect at the epigenetic, mRNA and protein levels. Materials & methods: Type 2 diabetes mellitus was induced in rats by streptozotocin and high-fat diet. Rats were treated with isorhamnetin (50 mg/kg/d) for 4 or 8 weeks. Fasting blood glucose, renal and lipid profiles were evaluated. Renal tissues were examined by light and electron microscopy. Autophagy genes ( FYCO1, ULK, TECPR1 and  WIPI2) and miR-15b, miR-34a and miR-633 were assessed by qRT-PCR, and LC3A/B by immunoblotting. Results: Isorhamnetin improved fasting blood glucose, renal and lipid profiles with increased autophagosomes in renal tissues. It suppressed miRNA regulation of autophagy genes Conclusion: We propose a molecular mechanism for the isorhamnetin renoprotective effect by modulation of autophagy epigenetic regulators.


World ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 49-61
Author(s):  
Pouya Molaei ◽  
Liyaning Tang ◽  
Mary Hardie

The walkability of urban areas is an important criterion related to the level of physical activity and public health of citizens. This research aims to measure this parameter in Golsar town located in Rasht, Iran. Two methods were used in this research: Street connectivity and International Physical Activity Questionnaire (IPAQ). The principal variables of street connectivity were measured in four districts of Golsar by Geographic Information System (GIS) to rank each one. Then, the acquired results were compared by the average walking time of the respondents of the questionnaire. The comparison explicitly indicated that there is a strong positive correlation between the measures of street connectivity and people’s tendency to walk. As well, District 1 had the highest value of connectivity and the highest average time for walking amongst the four districts. This supports the contention that walkability and the level of outdoor physical activities of people in each district are undoubtedly under the influence of the variables of street connectivity. Nevertheless, the evaluation of other indexes such as proximity, land use mix, safety, and density in Golsar, in future research. can expand our perception of the walkability of this region.


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