Evaluation of rosacea before and after intense pulsed laser treatment using reflectance confocal microscopy: case report

The dermoscopy and reflectance confocal microscopy (RCM) can provide new insights for diagnosis disease as non-invasive and easy-to-use tool. We described the dermoscopy and RCM characteristics of two patients with primary cutaneous amyloidosis (PCA) respectively. The dermoscopy characteristics were as follows: brownish macules with brown or white centers surrounded by hyperpigmented blotches, and a whitish scar-like center encircled by irregular brownish hyperpigmented spots or patches. The RCM features were increased melanin deposition in the basal layer, highly refractive structures with various shapes in the enlarged papillary dermis, and the increased pleomorphic structure of the dermal papillary ring. This is the first report the dermoscopy and RCM characteristics of PCA. We hope the characteristic dermoscopy and RCM appearances would provide a basis for doctors to diagnose and intervene earlier.

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Reflectance confocal microscopy features of regression in congenital naevus: case report

Journal of the European Academy of Dermatology and Venereology ◽

10.1111/jdv.13996 ◽

2016 ◽

Vol 31 (5) ◽

pp. e243-e245

Author(s):

F. Persechino ◽

B. De Pace ◽

A.M. Cesinaro ◽

G. Pellacani ◽

F. Farnetani

Keyword(s):

Case Report ◽

Confocal Microscopy ◽

Reflectance Confocal Microscopy

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Case report of a challenging medium‐sized congenital melanocytic nevus (CMN): Highlighting a role for reflectance confocal microscopy (RCM) for evaluating changing CMN in children

Pediatric Dermatology ◽

10.1111/pde.14846 ◽

2021 ◽

Author(s):

Stefanie Haefliger ◽

Pascale Guitera ◽

Bruna Melhoranse Gouveia ◽

Andrew J. Colebatch ◽

Richard A. Scolyer ◽

...

Keyword(s):

Case Report ◽

Confocal Microscopy ◽

Melanocytic Nevus ◽

Reflectance Confocal Microscopy ◽

Congenital Melanocytic Nevus

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Multicentric Reticulohistiocytosis with Dermatomyositis‐Like Features: A Case Report with Dermoscopy and Reflectance Confocal Microscopy Findings

Journal of Cutaneous Pathology ◽

10.1111/cup.14170 ◽

2021 ◽

Author(s):

Banu Farabi ◽

Marielle Jamgochian ◽

Babar K. Rao

Keyword(s):

Case Report ◽

Confocal Microscopy ◽

Reflectance Confocal Microscopy ◽

Multicentric Reticulohistiocytosis

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Oral Supplementation with Hydrolyzed Fish Cartilage Improves the Morphological and Structural Characteristics of the Skin: A Double-Blind, Placebo-Controlled Clinical Study

Molecules ◽

10.3390/molecules26164880 ◽

2021 ◽

Vol 26 (16) ◽

pp. 4880

Author(s):

Patrícia Maria Berardo Gonçalves Maia Campos ◽

Rodolfo Scarpino Barboza Franco ◽

Letícia Kakuda ◽

Gabriel Fernandes Cadioli ◽

Gabriela Maria D’Angelo Costa ◽

...

Keyword(s):

Confocal Microscopy ◽

Structural Characteristics ◽

Oral Treatment ◽

Reflectance Confocal Microscopy ◽

Double Blind ◽

Oral Supplementation ◽

Collagen Peptides ◽

Before And After ◽

The Face ◽

Clinical Benefits

Collagen and its peptides are natural ingredients used in food supplements and nutricosmetics with the claim of providing benefits for skin health and beauty. In this context, the aim of the present study was to evaluate the clinical efficacy of oral supplementation with hydrolyzed fish cartilage for the improvement of chronological and photoaging-induced skin changes. A total of 46 healthy females aged 45 to 59 years were enrolled and divided into two groups: G1—placebo and G2—oral treatment with hydrolyzed fish cartilage. Measurements of skin wrinkles, dermis echogenicity and thickness, and morphological and structural characteristics of the skin were performed in the nasolabial region of the face before and after a 90-day period of treatment using high-resolution imaging, ultrasound, and reflectance confocal microscopy image analyses. A significant reduction in wrinkles and an increase of dermis echogenicity were observed after a 90-day period of treatment with hydrolyzed fish cartilage compared to the placebo and baseline values. In addition, reflectance confocal microscopy (RCM) image analysis showed improved collagen morphology and reduced elastosis after treatment with hydrolyzed fish cartilage. The present study showed the clinical benefits for the skin obtained with oral supplementation with a low dose of collagen peptides from hydrolyzed fish cartilage.

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