The Effect of Chronic Intoxication with 2-Chloroethanol on Immune Responses, Function of Th1 and Th2 Lymphocytes and Blood Cytokine Concentrations

Author(s):  
Pavel Franzevich Zabrodskii
Author(s):  
P. F. Zabrodskii ◽  
V. V. Maslyakov ◽  
M. S. Gromov

In experiments on outbred albino rats, it was established that subacute intoxication with ethylene chlorohydrin (0.2 LD50 daily for 4 days) causes a decrease in Th1 and Th2 lymphocytes function to the same extent, diminishes parameters of humoral and cellular immune responses and the content of immunoregulatory cytokines IFN- , IL-2, IL-4 in blood, increases concentrations of pro-inflammatory cytokine IL-6 and anti-inflammatory cytokine IL-10.


2012 ◽  
Vol 1 (2) ◽  
pp. 0202
Author(s):  
Andrey A. Svistunov ◽  
Pavel F. Zabrodskii ◽  
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V.F. Grichin

2005 ◽  
Vol 18 (1) ◽  
pp. 133-144 ◽  
Author(s):  
K. Yamaki ◽  
H. Uchida ◽  
X. Li ◽  
R. Yanagisawa ◽  
H. Takano ◽  
...  
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Vaccine ◽  
2010 ◽  
Vol 28 (27) ◽  
pp. 4402-4410 ◽  
Author(s):  
Lin Yuan ◽  
Lihua Wu ◽  
Jian Chen ◽  
Qiang Wu ◽  
Songhua Hu
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2003 ◽  
Vol 92 (8) ◽  
pp. 1723-1729 ◽  
Author(s):  
Kouya Yamaki ◽  
Hiroyuki Uchida ◽  
Yoshiki Harada ◽  
Rie Yanagisawa ◽  
Hirohisa Takano ◽  
...  

10.1038/ni872 ◽  
2002 ◽  
Vol 4 (1) ◽  
pp. 78-86 ◽  
Author(s):  
Mara Messi ◽  
Isabella Giacchetto ◽  
Kinya Nagata ◽  
Antonio Lanzavecchia ◽  
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Immunology ◽  
1999 ◽  
Vol 97 (3) ◽  
pp. 506-514 ◽  
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Vandebriel ◽  
De Gruijl ◽  
Wolvers ◽  
Van Dijk ◽  
...  

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