On the results of the consideration and preparation for joint Russian-Ukrainian space experiments onboard the Russian segment of the International Space Station

2002 ◽  
Vol 8 (5-6) ◽  
pp. 5-8
Author(s):  
A.B. Kamelin ◽  
◽  
V.M. Kuntsevich ◽  
О.К. Cheremnykh ◽  
◽  
...  
Author(s):  
Fedor A. VORONIN

The development of Information Control System (ICS) of the Russian Segment of the International Space Station is considered. This Information Control System is intended for automatic and manual control of space experiments. To create high-tech conditions for scientific experiments on the ISS RS, RSC Energia performs operations for the ICS modernization on the Service Module, as well as the creation of ICS on the planned Multipurpose Laboratory Module and Science Power Module. The ICS modernization phases and principles are reviewed. The conduct of a series of high-tech scientific experiments was a practical result of the Service Module Information Control System (ICS) modernization. In 2014 two cameras were installed on the ISS. Today scientific experiment Icarus is being prepared for flight tests. The experience gained during experiments carried out allows to suggest that the ISS RS ICS will become a modern system allowing to implement the most ambitious experiments in the automatic mode on the ISS. Key words: Information Control System, ISS, space experiments, science hardware.


Author(s):  
O. V. Rybalchenko ◽  
O. G. Orlova ◽  
O. N. Vishnevskaya ◽  
V. V. Kapustina ◽  
I. L. Potokin ◽  
...  

Aim. Study the effect of microgravitation on the formation of Lactobacillus plantarum 8PA-3 bacterial biofilms in the conditions of space flight. Materials and methods. Information on the effect of microgravitation on the development of biofilms was obtained during study of L. plantarum 8PA-3 probiotic lactobacilli in special equipment in the process of execution of space experiments in the Russian segment of the International Space Station. Comparative analysis of growth of plankton and biofilm forms of cells developing in the conditions of space flight and surface conditions was carried out by microbiologic and electron-microscopy methods using scanning and transmission electron microscopy. Results. Accelerated dynamics of formation of L. plantarum 8PA-3 lactobacilli biofilm on the surface of polymer substrate was shown for the first time during the space experiment. Microbiological analysis of the bacterial culture has also confirmed the accelerated growth of L. plantarum 8PA-3 under microgravitation compared with surface conditions. Ultrastructure of plankton form of L. plantarum 8PA-3 taking part in formation of biofilms in conditions of microgravitation was detected for the first time in the space experiment. Conclusion. Data on comparative electron-microscopic analysis obtained in space experiments are important for scientific justification of the effect of microgravitation on bacterial communities developing as biofilms - the most natural form of existence of microorganisms. The results obtained could be taken into consideration during creation of novel antibacterial means and disinfectants as well as methods of treatment of surfaces of modules of piloted space complexes that could allow to clarify methods of effective prophylaxis of biofilm spread which pose a risk of health of the crew and normal functioning of equipment in the International Space Station.


2005 ◽  
Author(s):  
Danielle Paige Smith ◽  
Vicky E. Byrne ◽  
Cynthia Hudy ◽  
Mihriban Whitmore

2020 ◽  
Vol 91 (1) ◽  
pp. 41-45 ◽  
Author(s):  
Virginia. E. Wotring ◽  
LaRona K. Smith

INTRODUCTION: There are knowledge gaps in spaceflight pharmacology with insufficient in-flight data to inform future planning. This effort directly addressed in-mission medication use and also informed open questions regarding spaceflight-associated changes in pharmacokinetics (PK) and/or pharmacodynamics (PD).METHODS: An iOS application was designed to collect medication use information relevant for research from volunteer astronaut crewmembers: medication name, dose, dosing frequency, indication, perceived efficacy, and side effects. Leveraging the limited medication choices aboard allowed a streamlined questionnaire. There were 24 subjects approved for participation.RESULTS: Six crewmembers completed flight data collection and five completed ground data collection before NASA’s early study discontinuation. There were 5766 medication use entries, averaging 20.6 ± 8.4 entries per subject per flight week. Types of medications and their indications were similar to previous reports, with sleep disturbances and muscle/joint pain as primary drivers. Two subjects treated prolonged skin problems. Subjects also used the application in unanticipated ways: to note drug tolerance testing or medication holiday per research protocols, and to share data with flight surgeons. Subjects also provided usability feedback on application design and implementation.DISCUSSION: The volume of data collected (20.6 ± 8.4 entries per subject per flight week) is much greater than was collected previously (<12 per person per entire mission), despite user criticisms regarding app usability. It seems likely that improvements in a software-based questionnaire application could result in a robust data collection tool that astronauts find more acceptable, while simultaneously providing researchers and clinicians with useful data.Wotring VE, Smith LK. Dose tracker application for collecting medication use data from International Space Station crew. Aerosp Med Hum Perform. 2020; 91(1):41–45.


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