Validity and Reliability of EORTC QLQ C-30 Questionnaire in Assessing Quality of Life of Gynecological Cancer Patients in Sanglah Hospital Denpasar

Abstract Objective The Functional Assessment of Cancer Therapy—Cognitive Function (FACT-Cog) is a questionnaire that is used to evaluate the quality of life and cognitive functions according to individual self-reports. The aim of this study was to investigate the validity and reliability of the Turkish version of the FACT-Cog. Methods Cancer patients who were treated with chemo or radiotherapy and had a score of 24/30 and more in Mini-Mental State Examination (MMSE) were included in this study. Cognitive functions assessed with the FACT-Cog and the European Organization of Research and Treatment of Cancer Quality of Life Core Questionnaire Core 30: Cognitive Function subscale (EORTC QLQ-CF). Results One hundred and forty cancer patients [female = 87 (62.1%), male = 53 (37.9%)] were included. The mean age of the participants was 47.93 ± 11.90 years. The Cronbach's α of the FACT-Cog scale was 0.82. Test–retest intraclass correlation coefficient values of the FACT-Cog questionnaire were varied from 0.855 to 0.954. There were found low correlations between the total score of the FACT-Cog and the MMSE (r = 0.26, p = 0.002), and moderate correlations between the EORTC QLQ-CF subscale and the FACT-Cog (r = −0.43; p < 0.001). Significance of results It showed the validity and reliability of the Turkish version of the FACT-Cog questionnaire for cancer patients. It may be beneficial to use this questionnaire for the effects of cancer treatment.

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Multivitamins do not improve radiation therapy related fatigue: Results of a double-blind randomized cross-over trial

Journal of Clinical Oncology ◽

10.1200/jco.2007.25.18_suppl.9103 ◽

2007 ◽

Vol 25 (18_suppl) ◽

pp. 9103-9103

Author(s):

R. Kaliks-Guendelmann ◽

M. P. Oliveira Campos ◽

Â. B. Souza Fêde ◽

C. G. Bensi ◽

D. C. Trufelli ◽

...

Keyword(s):

Quality Of Life ◽

Radiation Therapy ◽

Cancer Patients ◽

Common Symptom ◽

Energy Methods ◽

Double Blind ◽

C 30 ◽

Radiation Treatments ◽

Eortc Qlq

9103 Background: Fatigue is a common symptom in cancer patients including those receiving radiation therapy. Multivitamins are broadly used by cancer patients to improve overall health and energy. Methods: We conducted a double blind randomized cross- over trial of multivitamins versus placebo in patients with breast cancer (BC) undergoing radiation therapy (Rxt) in order to evaluate if multivitamins would affect fatigue and quality of life. We randomized patients at the beginning of Rxt treatment to either placebo or Centrum Silver (Wyeth-Whitehall laboratory). At the middle of the radiation treatments patients were switched from placebo to multivitamins and vice versa. Patients answered to the EORTC QLQ C-30 quality of life (QOL) and Chalder fatigue questionnaires at the beginning, the time of switching and at the end of Rxt. Results: We randomized forty patients to either placebo or Centrum Silver. At the middle of the radiation treatments patients were switched from placebo to MVi and vice versa. Patients answered the EORTC QLQ C-30 quality of life (QOL) and Chalder fatigue questionnaires at the beginning, the middle and at the end of Rxt. Both groups experienced decreases in general (p = 0.009; p = 0.001) and physical fatigue scores (p = 0.031; p = 0.029) at the end of the course of placebo compared to the assessment prior to this treatment. We also observed significant improvements in functional (p = 0.026) and symptoms (p = 0.016) score scales of the QOL questionnaire in the patients on placebo. No significant changes were elicited with the use of MVi. We also observed significantly lower rates of fatigue in the patients who had just finished a course of placebo as compared to patients finishinga course of MVi (0 vs 25% p = 0.035). Conclusions: MVi do not improve radiation related fatigue in patients with BC. No significant financial relationships to disclose.

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The Exploration of Health-Related Quality of Life

Clinical Nursing Research ◽

10.1177/1054773815600665 ◽

2016 ◽

Vol 26 (1) ◽

pp. 114-131 ◽

Cited By ~ 5

Author(s):

Shu-Fen Wu ◽

Hong-Yi Tong ◽

Yuen-Yee kan ◽

Sheng-Hui Su ◽

Meng-Chi Lee ◽

...

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Gynecological Cancer ◽

Gynecologic Cancer ◽

Symptom Distress ◽

Life Questionnaire ◽

European Organization ◽

Eortc Qlq ◽

Distress Scale

The purpose of this study was to explore quality of life (QoL) and the factors influencing QoL in gynecological cancer patients. One hundred sixty-seven patients with gynecologic cancers were recruited from a district hospital in Southern Taiwan. The instruments used included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 Version 3.0 in Chinese (EORTC QLQ-C30), the Symptom Distress Scale, and demographic characteristics and disease-related variables. The results showed that the mean score for the QLQ-C30 was 61.13 ( SD = 22.71). In the stepwise regression model, two factors predicted overall global QoL: symptom distress (33.8%) and current occupation (2.2%). These predictors accounted for 36.0% of the total variance. These results showed that symptom distress was a predictor of QoL. This study provides a reference for use when designing improved educational care programs that reduce patient symptom distress and enhance gynecologic cancer patients’ QoL.

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Construct Validity and Reliability of the European Organization for Research and Treatment of Cancer Quality of Life Tool Among Colorectal Cancer Patients in Ethiopia

10.21203/rs.3.rs-623547/v1 ◽

2021 ◽

Author(s):

Lidya Genene Abebe ◽

Abigiya Wondimagegnehu ◽

Aynalem Abraha Woldemariam ◽

Bizu Gelaye ◽

Eva Johanna Kantelhardt ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Construct Validity ◽

Cancer Patients ◽

Life Questionnaire ◽

Validity And Reliability ◽

European Organization ◽

Eortc Qlq ◽

Colorectal Cancer Patients

Abstract Background: Colorectal cancer and its treatments can have a detrimental effect on patients’ quality of life. The European Organization for Research and Treatment of Cancer Quality of Life questionnaire (EORTC-QLQ) was developed to assess quality of life among colorectal cancer patients and is used worldwide. However, the tool has not been translated into a local language or validated in the Ethiopian context. Therefore, this study aimed to examine the psychometric properties of the EORTC-QLQ in Ethiopia among colorectal cancer patients.Methods: A cross-sectional study was conducted in a major referral hospital in Addis Ababa, Ethiopia from March to May, 2020. A total of 158 colorectal cancer patients were consecutively included. The construct validity was assessed using Multitrait Scale Analysis, convergent validity, and relationship with functional outcomes. The internal consistency was examined using Cronbach’s alpha.Result: Among the participants, 52.2% were men, with a median age of 46 years (IQR = 17.7 years). The time needed to complete the EORTC-QLQ was less than 20 minutes. The item-total correlation alpha values ranged from 0.47–0.91. All item correlations within their scales were greater than 0.4 except for the Blood and Mucus in Stool scale. The value of correlation coefficients between all items and their own domain were higher than other domains, except for the Blood and Mucus in Stool scale. The correlation between the core questionnaire and the colorectal tool ranged from -0.453–0.581. The tool showed a significant difference between stoma and non-stoma patients, and between patients who had good physical function and those who did not.Conclusion: Except for the Blood and Mucus in Stool scale, the construct validity and reliability of all scales were supported. Therefore, the Amharic version of the tool can be used to assess health related quality of life in Ethiopian colorectal cancer patients. However, due to the low correlation between items in the Blood and Mucus in Stool scale, we recommend that these items are treated as a single item.

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Praying correlates with higher quality of life: results from a survey on complementary/alternative medicine use among a group of Brazilian cancer patients

Sao Paulo Medical Journal ◽

10.1590/s1516-31802004000200005 ◽

2004 ◽

Vol 122 (2) ◽

pp. 60-63 ◽

Cited By ~ 18

Author(s):

Eliana Sueco Tibana Samano ◽

Patricia Taschner Goldenstein ◽

Lia de Melo Ribeiro ◽

Fabio Lewin ◽

Edgar Santiago Valesin Filho ◽

...

Keyword(s):

Quality Of Life ◽

Alternative Medicine ◽

Cancer Patients ◽

Complementary Alternative Medicine ◽

Life Questionnaire ◽

Medicine Use ◽

C 30 ◽

Eortc Qlq ◽

Life Type

CONTEXT: The use of complementary/alternative medicine has been little studied in Brazil. OBJECTIVE: The purpose of this study was to determine the prevalence of complementary/alternative medicine use among a group of Brazilian cancer patients and correlate these findings with the patients' quality of life. TYPE OF STUDY: Descriptive. SETTING: Oncology Institute of the Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil. PARTICIPANTS: 100 cancer patients. PROCEDURES: The EORTC QLQ C-30 quality of life questionnaire was applied together with another questionnaire on the use of complementary/alternative medicine. MAIN MEASUREMENTS: Use of complementary/alternative medicine and quality of life. RESULTS: 89% of the patients had already used complementary/alternative medicine, 63% were currently using it and most of them (77.7%) believed in the efficacy of complementary/alternative medicine for their treatment. The type most used was individual prayer (77.5%). We found a significant association between believing in the efficacy of complementary/alternative medicine and praying (individually or in groups), in comparison with better scores on the functional (p = 0.001) and overall health (p = 0.001) quality of life scales. Multivariate analysis confirmed these findings regarding praying and also showed that believing in complementary/alternative medicine correlated significantly with functional and symptom quality of life scores. CONCLUSION: The prevalence of complementary/alternative medicine use in this group of cancer patients was high. Praying and belief in the efficacy of complementary/alternative medicine correlated significantly with an overall better quality of life, and therefore these practices should not be discouraged by physicians. New prospective studies should be conducted in order to better characterize the efficacy of such alternative therapeutic approaches.

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A Review of Psychoeducational Interventions to Improve Sexual Functioning, Quality of Life, and Psychological Outcomes in Gynecological Cancer Patients

Cancer Nursing ◽

10.1097/ncc.0000000000000234 ◽

2016 ◽

Vol 39 (1) ◽

pp. 20-31 ◽

Cited By ~ 10

Author(s):

Ka Ming Chow ◽

Joanne C. Y. Chan ◽

Kai K. C. Choi ◽

Carmen W. H. Chan

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Sexual Functioning ◽

Gynecological Cancer ◽

Psychological Outcomes ◽

Psychoeducational Interventions

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Development, characteristics and validity of the EORTC QLQ-PR25 and the FACT-P for assessment of quality of life in prostate cancer patients

Journal of Comparative Effectiveness Research ◽

10.2217/cer.14.41 ◽

2014 ◽

Vol 3 (5) ◽

pp. 523-531 ◽

Cited By ~ 6

Author(s):

Dominic Chu ◽

Marko Popovic ◽

Edward Chow ◽

David Cella ◽

Jennifer L Beaumont ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Cancer Patients ◽

Eortc Qlq

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Predictive factors of overall quality of life in advanced cancer patients using EORTC QLQ-C30

Expert Review of Pharmacoeconomics & Outcomes Research ◽

10.1586/14737167.2014.864560 ◽

2013 ◽

Vol 14 (1) ◽

pp. 139-146 ◽

Cited By ~ 4

Author(s):

Gemma Cramarossa ◽

Liang Zeng ◽

Liying Zhang ◽

Ling-Ming Tseng ◽

Ming-Feng Hou ◽

...

Keyword(s):

Quality Of Life ◽

Cancer Patients ◽

Advanced Cancer ◽

Predictive Factors ◽

Advanced Cancer Patients ◽

Eortc Qlq C30 ◽

Eortc Qlq

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Psychometric properties of the EORTC Quality of Life Questionnaire in inpatient cancer rehabilitation in Germany

Palliative & Supportive Care ◽

10.1017/s1478951504040179 ◽

2004 ◽

Vol 2 (2) ◽

pp. 115-124 ◽

Cited By ~ 6

Author(s):

JÖRG DIRMAIER ◽

SILKE ZAUN ◽

UWE KOCH ◽

TIMO HARFST ◽

HOLGER SCHULZ

Keyword(s):

Quality Of Life ◽

Psychometric Properties ◽

Cancer Patients ◽

Scale Structure ◽

Cancer Rehabilitation ◽

Life Questionnaire ◽

European Organization ◽

Eortc Qlq C30 ◽

Eortc Qlq

Objective: Recent years have shown an increase in the use of questionnaires measuring health-related quality of life to verify the quality of treatment in the field of oncology. An often used cancer-specific questionnaire is the “Quality of Life Core Questionnaire of the European Organization for the Research and Treatment of Cancer” (EORTC QLQ-C30). The purpose of this study is to analyze the psychometric properties of the EORTC QLQ-C30 (version 1) in order to determine the feasibility and appropriateness for its use in inpatient cancer rehabilitation in Germany with heterogeneous diagnoses.Methods: The questionnaire was administrated to a sample of 972 cancer patients at the beginning of treatment and to 892 patients after treatment. Besides descriptive analysis, the statistical analyses include confirmatory analysis and the multitrait/multimethod approach to test the questionnaire's postulated scale structure (factorial validity) and its reliability (internal consistencies). The analysis also includes a comparison of responsiveness indices (effect size, reliable change index) to test the sensitivity of the instrument.Results: The EORTC QLQ-C30 showed satisfactory levels of reliability and sensitivity, but the postulated scale structure could not be confirmed. The results illustrate that the varimax-rotated solution of a principal component analysis does not confirm the scale structure postulated by the authors. Correspondingly, the selected fit indices within the scope of the confirmatory factor analysis do not show satisfactory results either.Significance of results: We therefore consider version 1 of the EORTC QLQ-C30 to be only limitedly useful for the routine assessment of changes in the quality of life of cancer patients in inpatient rehabilitation in Germany, especially because of the instrument's length and possible redundancies. For this reason, a scoring procedure limited to a subset of items is suggested, revealing satisfactory to good psychometric indices. However, further psychometric tests are necessary, especially with regard to validity and sensitivity.

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