scholarly journals Construct Validity and Reliability of the European Organization for Research and Treatment of Cancer Quality of Life Tool Among Colorectal Cancer Patients in Ethiopia

2021 ◽  
Author(s):  
Lidya Genene Abebe ◽  
Abigiya Wondimagegnehu ◽  
Aynalem Abraha Woldemariam ◽  
Bizu Gelaye ◽  
Eva Johanna Kantelhardt ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Construct Validity ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Validity And Reliability ◽  
European Organization ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Background: Colorectal cancer and its treatments can have a detrimental effect on patients’ quality of life. The European Organization for Research and Treatment of Cancer Quality of Life questionnaire (EORTC-QLQ) was developed to assess quality of life among colorectal cancer patients and is used worldwide. However, the tool has not been translated into a local language or validated in the Ethiopian context. Therefore, this study aimed to examine the psychometric properties of the EORTC-QLQ in Ethiopia among colorectal cancer patients.Methods: A cross-sectional study was conducted in a major referral hospital in Addis Ababa, Ethiopia from March to May, 2020. A total of 158 colorectal cancer patients were consecutively included. The construct validity was assessed using Multitrait Scale Analysis, convergent validity, and relationship with functional outcomes. The internal consistency was examined using Cronbach’s alpha.Result: Among the participants, 52.2% were men, with a median age of 46 years (IQR = 17.7 years). The time needed to complete the EORTC-QLQ was less than 20 minutes. The item-total correlation alpha values ranged from 0.47–0.91. All item correlations within their scales were greater than 0.4 except for the Blood and Mucus in Stool scale. The value of correlation coefficients between all items and their own domain were higher than other domains, except for the Blood and Mucus in Stool scale. The correlation between the core questionnaire and the colorectal tool ranged from -0.453–0.581. The tool showed a significant difference between stoma and non-stoma patients, and between patients who had good physical function and those who did not.Conclusion: Except for the Blood and Mucus in Stool scale, the construct validity and reliability of all scales were supported. Therefore, the Amharic version of the tool can be used to assess health related quality of life in Ethiopian colorectal cancer patients. However, due to the low correlation between items in the Blood and Mucus in Stool scale, we recommend that these items are treated as a single item.

scholarly journals QUALITY OF LIFE AMONG COLORECTAL CANCER PATIENTS AT THAI NGUYEN ONCOLOGY CENTER

2021 ◽  
Vol 62 (4) ◽  
Author(s):  
Nguyen To Quynh Chau ◽  
Nguyen Manh Tuan ◽  
Nguyen Thanh Nhai ◽  
Nguyen Thi Ngan ◽  
Tran Bao Ngoc
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Cross Sectional Study ◽  
Functional Score ◽  
Cross Sectional ◽  
European Organization ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Aim: To describe quality life’s colorectal cancer patients who are being treated at Thai Nguyenoncology center from June 2020 to August 2020.Objects and method: The descriptive cross- sectional study was conducted over 68 patientsdiagnosed with colorectal cancer by face to face interview using the European Organization forResearch and Treatment of Cancer (EORTC) QLQ-C30 and the EORTC QLQ-CR29.Results: Mean of overall health score was 51,96±18,78; mean of functional score was 21,49±12,42(1,71–47,06). In functional sector, social function was scored lowest. In symptomatic scale, appetiteloss was scored highest (47,06).Conclusion: Quality of life of colorectal cancer patients was medium level. Highest scores wereobserved for appetite loss and fatigue. To improve quality life’s patients, medical staffs need to keepenhancing symptoms and function for patients during treatment.

scholarly journals Validation of the Arabic version of the EORTC Colorectal (CR29) module in Moroccan  colorectal cancer patients

2021 ◽  
Author(s):  
Yacir El Alami ◽  
Houda Bachri ◽  
Hajar Essangri ◽  
Said Benamer ◽  
Amine Benkabbou ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Arabic Version ◽  
Frequency Scale ◽  
Moroccan Arabic ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Purpose: Quality of life outcomes are a focal endpoint of cancer treatment strategies which can be evaluated through patient-related outcome measures (PROMs). We aim to validate the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Colorectal cancer patients (EORTC QLQ CR-29).Methods: Following translation to Moroccan Arabic, the QLQ CR-29 was administered to patients treated for colorectal cancer (CRC) in the national institute of oncology. Psychometric properties were tested by measuring Cronbach’s alpha coefficient for reliability and Intraclass correlation coefficient(ICC) to examine test-retest reproducibility. The multitrait-scaling analysis was performed to demonstrate the validity of the instrument and the ability to discriminate between different patient groups was tested using known-groups comparison.Results: In total, 221 patients were included in our study and 34 patients completed the questionnaire twice. The urinary Frequency scale and Stool Frequency scale had good internal consistency with alpha Cronbach coefficients of 0,79 and 0,83 respectively, whereas the coefficient was moderately lower for the Blood and Mucus in Stool scale (0,61) and the Body Image scale (0,67). The ICCs ranged from 0,88 to 1 indicating good to excellent reproducibility. In multitrait scaling analyses, the criterion for item convergent and divergent validity was satisfactory. The known-group comparison showed statistically significant differences between patients according to age, gender, stoma status, tumor location, and radiotherapy. Conclusion: The Moroccan Arabic version of the EORTC QLQ-CR29 is a valid and reliable tool and can be used for research and clinical purposes in Moroccan CRC patients.

Validation of the Arabic version of the EORTC Colorectal (CR29) module in Moroccan  colorectal cancer patients

2020 ◽  
Author(s):  
Yacir El Alami ◽  
Houda Bachri ◽  
Hajar Essangri ◽  
Said Benamer ◽  
Amine Benkabbou ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Colorectal Cancer ◽  
Cancer Patients ◽  
Life Questionnaire ◽  
Arabic Version ◽  
Frequency Scale ◽  
Moroccan Arabic ◽  
Eortc Qlq ◽  
Colorectal Cancer Patients

Abstract Purpose Quality of life outcomes are a focal endpoint of cancer treatment strategies which can be evaluated through patient-related outcome measures (PROMs). We aim to validate the Moroccan Arabic version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire for Colorectal cancer patients (EORTC QLQ CR-29). Methods Following translation to Moroccan Arabic, the QLQ CR-29 was administered to patients treated for colorectal cancer (CRC) in the national institute of oncology. Psychometric properties were tested by measuring Cronbach’s alpha coefficient for reliability and Intraclass correlation coefficient(ICC) to examine test-retest reproducibility. The multitrait-scaling analysis was performed to demonstrate the validity of the instrument and the ability to discriminate between different patient groups was tested using known-groups comparison. Results In total, 221 patients were included in our study and 34 patients completed the questionnaire twice. The urinary Frequency scale and Stool Frequency scale had good internal consistency with alpha Cronbach coefficients of 0,79 and 0,83 respectively, whereas the coefficient was moderately lower for the Blood and Mucus in Stool scale (0,61) and the Body Image scale (0,67). The ICCs ranged from 0,88 to 1 indicating good to excellent reproducibility. In multitrait scaling analyses, the criterion for item convergent and divergent validity was satisfactory. The known-group comparison showed statistically significant differences between patients according to age, gender, stoma status, tumor location, and radiotherapy. Conclusion The Moroccan Arabic version of the EORTC QLQ-CR29 is a valid and reliable tool and can be used for research and clinical purposes in Moroccan CRC patients.

Psychometric properties of the EORTC Quality of Life Questionnaire in inpatient cancer rehabilitation in Germany

2004 ◽  
Vol 2 (2) ◽  
pp. 115-124 ◽  
Author(s):  
JÖRG DIRMAIER ◽  
SILKE ZAUN ◽  
UWE KOCH ◽  
TIMO HARFST ◽  
HOLGER SCHULZ
Keyword(s):  
Quality Of Life ◽  
Psychometric Properties ◽  
Cancer Patients ◽  
Scale Structure ◽  
Cancer Rehabilitation ◽  
Life Questionnaire ◽  
European Organization ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Objective: Recent years have shown an increase in the use of questionnaires measuring health-related quality of life to verify the quality of treatment in the field of oncology. An often used cancer-specific questionnaire is the “Quality of Life Core Questionnaire of the European Organization for the Research and Treatment of Cancer” (EORTC QLQ-C30). The purpose of this study is to analyze the psychometric properties of the EORTC QLQ-C30 (version 1) in order to determine the feasibility and appropriateness for its use in inpatient cancer rehabilitation in Germany with heterogeneous diagnoses.Methods: The questionnaire was administrated to a sample of 972 cancer patients at the beginning of treatment and to 892 patients after treatment. Besides descriptive analysis, the statistical analyses include confirmatory analysis and the multitrait/multimethod approach to test the questionnaire's postulated scale structure (factorial validity) and its reliability (internal consistencies). The analysis also includes a comparison of responsiveness indices (effect size, reliable change index) to test the sensitivity of the instrument.Results: The EORTC QLQ-C30 showed satisfactory levels of reliability and sensitivity, but the postulated scale structure could not be confirmed. The results illustrate that the varimax-rotated solution of a principal component analysis does not confirm the scale structure postulated by the authors. Correspondingly, the selected fit indices within the scope of the confirmatory factor analysis do not show satisfactory results either.Significance of results: We therefore consider version 1 of the EORTC QLQ-C30 to be only limitedly useful for the routine assessment of changes in the quality of life of cancer patients in inpatient rehabilitation in Germany, especially because of the instrument's length and possible redundancies. For this reason, a scoring procedure limited to a subset of items is suggested, revealing satisfactory to good psychometric indices. However, further psychometric tests are necessary, especially with regard to validity and sensitivity.

Test/retest study of the European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire.

1995 ◽  
Vol 13 (5) ◽  
pp. 1249-1254 ◽  
Author(s):  
M J Hjermstad ◽  
S D Fossa ◽  
K Bjordal ◽  
S Kaasa
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Reliability And Validity ◽  
Life Questionnaire ◽  
European Organization ◽  
Retest Reliability ◽  
Eortc Qlq C30 ◽  
Eortc Qlq ◽  
Test Retest Reliability

PURPOSE The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated instrument that assesses health-related quality of life (HRQOL) in cancer patients. It is used in cancer clinical trials in Europe, Canada, and the United States, and has demonstrated high reliability and validity in different groups of cancer patients. Despite thorough testing of reliability and validity, we have not identified any reports on its test/retest reliability; thus, a test/retest study was performed at the Norwegian Radium Hospital (NRH). MATERIALS AND METHODS Cancer patients from the outpatient clinic who were off treatment for > or = 3 months were eligible for the study. The EORTC QLQ-C30 was given to the patients when they presented for their visit. The second questionnaire was received by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to participate and 190 (73%) completed both questionnaires. RESULTS The test/retest reliability measured by Pearson's correlation coefficient was high for all functional scales, with a range from .82 for cognitive and role function to .91 for physical function. The r value for global HRQOL was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the coefficients were .63, .83, and .86, respectively. The single-item coefficients ranged from .72 for diarrhea to .84 for financial impact. The Spearman rank correlation was in the same range for all dimensions. CONCLUSION The EORTC QLQ-C30 seems to yield high test/retest reliability in patients with various cancer diagnoses whose condition is not expected to change during the time of measurement.

scholarly journals Quality of life among Ethiopian cancer patients

2020 ◽  
Vol 28 (11) ◽  
pp. 5469-5478
Author(s):  
Yemataw Wondie ◽  
Andreas Hinz
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Depression Scale ◽  
Developed Countries ◽  
Anxiety And Depression ◽  
Life Questionnaire ◽  
European Organization ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Abstract Purpose Cancer is of increasing prevalence in less-developed countries. However, research on the patients’ quality of life (QoL) in these countries is very limited. The aim of this study was to examine QoL of cancer patients in Africa. Method A sample of 256 cancer patients treated in an Ethiopian hospital was examined with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire EORTC QLQ-C30, the Multidimensional Fatigue Inventory, and the Hospital Anxiety and Depression Scale. A group of 1664 German cancer patients served as a comparison group. Results Most of the scales of the EORTC QLQ-C30 showed acceptable reliability in the Ethiopian sample. Compared with the German cancer patients, the Ethiopian patients showed lower QoL in most dimensions, especially in financial difficulties, physical functioning, pain, and appetite loss (effect sizes between 0.52 and 0.75). Illiteracy, tumor stage, and treatment (surgery and chemotherapy) were associated with QoL in the Ethiopian sample. QoL was strongly correlated with fatigue, anxiety, and depression. Conclusion The EORTC QLQ-C30 is a suitable instrument for measuring QoL in Ethiopia. The detriments in QoL in the Ethiopian patients indicate specific cancer care needs for the patients in a developing country.

Quality of Life in Head and Neck Cancer Patients: Validation of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-H&N35

1999 ◽  
Vol 17 (3) ◽  
pp. 1008-1008 ◽  
Author(s):  
Kristin Bjordal ◽  
Eva Hammerlid ◽  
Marianne Ahlner-Elmqvist ◽  
Alexander de Graeff ◽  
Morten Boysen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck ◽  
Cancer Patients ◽  
Performance Status ◽  
Compliance Rate ◽  
Life Questionnaire ◽  
European Organization ◽  
Quality Of Life Questionnaire ◽  
Eortc Qlq

PURPOSE: The aim of this study was to define the scales and test the validity, reliability, and sensitivity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ)-H&N35, a questionnaire designed to assess the quality of life of head and neck (H&N) cancer patients in conjunction with the general cancer-specific EORTC QLQ-C30. PATIENTS AND METHODS: Questionnaires were given to 500 H&N cancer patients from Norway, Sweden, and the Netherlands as part of two prospective studies. The patients completed the questionnaires before, during (Norway and Sweden only), and after treatment, yielding a total of 2070 completed questionnaires. RESULTS: The compliance rate was high, and the questionnaires were well accepted by the patients. Seven scales were constructed (pain, swallowing, senses, speech, social eating, social contact, sexuality). Scales and single items were sensitive to differences between patient subgroups with relation to site, stage, or performance status. Most scales and single items were sensitive to changes, with differences of various magnitudes according to the site in question. The internal consistency, as assessed by Cronbach's alpha coefficient, varied according to assessment point and within subsamples of patients. A low overall alpha value was found for the speech and the senses scales, but values were higher in assessments of patients with laryngeal cancer and in patients with nose, sinus, and salivary gland tumors. Scales and single items in the QLQ-H&N35 seem to be more sensitive to differences between groups and changes over time than do the scales and single items in the core questionnaire. CONCLUSION: The QLQ-H&N35, in conjunction with the QLQ-C30, provides a valuable tool for the assessment of health-related quality of life in clinical studies of H&N cancer patients before, during, and after treatment with radiotherapy, surgery, or chemotherapy.

The Exploration of Health-Related Quality of Life

2016 ◽  
Vol 26 (1) ◽  
pp. 114-131 ◽  
Author(s):  
Shu-Fen Wu ◽  
Hong-Yi Tong ◽  
Yuen-Yee kan ◽  
Sheng-Hui Su ◽  
Meng-Chi Lee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Gynecological Cancer ◽  
Gynecologic Cancer ◽  
Symptom Distress ◽  
Life Questionnaire ◽  
European Organization ◽  
Eortc Qlq ◽  
Distress Scale

The purpose of this study was to explore quality of life (QoL) and the factors influencing QoL in gynecological cancer patients. One hundred sixty-seven patients with gynecologic cancers were recruited from a district hospital in Southern Taiwan. The instruments used included the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core-30 Version 3.0 in Chinese (EORTC QLQ-C30), the Symptom Distress Scale, and demographic characteristics and disease-related variables. The results showed that the mean score for the QLQ-C30 was 61.13 ( SD = 22.71). In the stepwise regression model, two factors predicted overall global QoL: symptom distress (33.8%) and current occupation (2.2%). These predictors accounted for 36.0% of the total variance. These results showed that symptom distress was a predictor of QoL. This study provides a reference for use when designing improved educational care programs that reduce patient symptom distress and enhance gynecologic cancer patients’ QoL.

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