PATENT DUCTUS ARTERIOSUS IN INFANCY

PEDIATRICS ◽  
1954 ◽  
Vol 13 (4) ◽  
pp. 357-362
Author(s):  
ROBERT A. LYON ◽  
SAMUEL KAPLAN

Patent ductus arteriosus produces symptoms in infancy which vary widely in kind and severity. Five patients observed during the past five years have been described briefly to illustrate these variations. One infant died at the age of one month with an aneurysm of the ductus. Another patient, with atypical signs, had a sevede degree of congestive failure until surgical treatment provided dramatic relief. In the other patients symptoms were limited to retardation of growth, frequent respiratory infections and atypical murmurs until the later months of infancy. In spite of the variation of physical signs and of the radiologic and electrocardiographic findings, an accurate diagnosis can often be made early in life. When doubt exists, and especially in infants suffering from cardiac failure, cardiac catheterization, aortography or angiocardiography must be employed to secure information necessary for immediate surgical treatment. Emphasis is placed upon the fact that patent ductus can be the sole lesion causing congestive failure in infancy.

2020 ◽  
Vol 30 (12) ◽  
pp. 1943-1945
Author(s):  
Semih Murat Yucel ◽  
Irfan Oguz Sahin

AbstractDuctus arteriosus is an essential component of fetal circulation. Due to occurring changes in the cardiopulmonary system physiology after birth, ductus arteriosus closes. Patent ductus arteriosus can be closed by medical or invasive (percutaneous or surgical) treatment methods. Percutaneous or surgical closure of patent ductus arteriosus can be performed for the cases that medical closure failed. Surgical treatment is often preferred method for closure of patent ductus arteriosus in the neonatal period. The most common surgical complications are pneumothorax, recurrent laryngeal nerve injury, bleeding, and recanalisation. A very rare surgical complication is left pulmonary artery ligation that has been presented in a few cases in the literature. Echocardiography control should be performed in the early post-operative period, especially in patients with clinical suspicion. If reoperation is required, it should never be delayed. We report a newborn patient whose left pulmonary artery ligated accidentally during patent ductus arteriosus closure surgery and surgical correction of this complication at the early post-operative period.


1984 ◽  
Vol 18 (1) ◽  
pp. 52-55 ◽  
Author(s):  
Ronald P. Evens

Nonsteroidal anti inflammatory drugs (NSAIDs) have several salient indications outside of their role in rheumatology. Two major uses are treatment of dysmenorrhea and patent ductus arteriosus. Other established roles encompass treatment of fever, pain, Banter's syndrome, and thromboembolic disorders. Animal and human studies are being done on the use of NSAIDs in cancer, diabetes, psoriasis, and shock, just to name a few investigative areas. NSAIDs are not a panacea nor are they wonder drugs to be used indiscriminately. When these drugs first were marketed in the 1970s, they were considered safe agents with little toxicity. However, the side-effect profile of the NSAIDs has been, and continues to be, better identified over the past few years and warrants judicious use of these drugs. Their adverse effects potentially include gastric distress (possibly hemorrhage), allergic urticaria or bronchospasm in asthma patients, azotemia, arrested labor, skin reactions, and water retention. NSAIDs are relatively safe agents with a growing list of new indications. Future clinical evaluation holds the key to the balance between their emerging toxicities and indications.


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