COXSACKIE B5 INFECTIONS WITH EXANTHEMS

PEDIATRICS ◽  
1963 ◽  
Vol 31 (3) ◽  
pp. 455-462
Author(s):  
James D. Cherry ◽  
A Martin Lerner ◽  
Jerome O. Klein ◽  
Maxwell Finland

Seven cases of Coxsackie B5 virus infection with exanthem observed at the Boston City Hospital during the late summer of 1961, are reported. The virus was isolated from six of the patients and a fourfold or greater rise in titer of hemagglutinin-inhibiting antibodies (HIA) to this virus was demonstrated in five of these six cases. In the seventh patient there was a significant rise in HIA titer, but attempts to isolate the virus were unsuccessful. The illness in these patients was characterized by a moderate fever, usually of 2 to 3 days duration with the fine, erythematous maculopapular eruption involving mostly the face and trunk, appearing toward the end of the febrile period, and somewhat resembling exanthem subitum. There was also some cervical and occipital lymph node enlargement. In 49 pairs of bloods obtained from mothers and infants (umbilical cord) at the time of delivery, the titers of HIA to Coxsackie B5 virus in the maternal sera were usually fourfold to eightfold greater than in the sera of corresponding umbilical cord blood. HIA titers of 1:80 or higher against Coxsackie B5 virus were demonstrated in 65% of these maternal sera, but only in 2 of 75 sera (2.7%) obtained from infants and children who did not have a rash during the summer of 1961.

PEDIATRICS ◽  
1956 ◽  
Vol 17 (4) ◽  
pp. 576-577

The Clifford G. Grulee Award of the American Academy of Pediatrics was created by the Executive Board in honor of Dr. Grulee upon his retirement as Executive Secretary in 1951. The Award is made each year, if a suitable recipient is found, for outstanding service to the American Academy of Pediatrics. The actual award presentation is made at the annual business meeting and shall be made by Dr. Grulee as long as he is able to do so, or by the President of the Academy. The Award consists of a handsome gold medal bearing the Insignia of the Academy and the inscription "Clifford G. Grulee Award" on the face of the medal and on the obverse side the name of the recipient with the inscription "For outstanding service to the American Academy of Pediatrics." Presentation of the Grulee Award for 1955 was made to Dr. Herbert E. Coe of Seattle by Dr. Grulee with the following remarks: "Herbert E. Coe has been a Fellow in the American Academy of Pediatrics since 1932. In spite of his youthful appearance, Dr. Coe has been practicing medicine for almost 50 years, having graduated from the University of Michigan School of Medicine in 1906. He interned and did residencies at the Boston Children's Hospital and the Boston City Hospital. Since 1920 Dr. Coe has limited his work to pediatric surgery and is recognized as one of the first to so specialize in the United States. He is also one of the few pediatric surgeons to be certified by the American Board of Pediatrics, having passed the Pediatric Board examinations in 1936. "He has served as Chief of Staff at the Children's Orthopedic Hospital of Seattle and as Chief of Children's Surgery at the Seattle City Hospital. Dr. Coe, in addition to being a Fellow of the American Academy of Pediatrics, is also a Fellow of the American College of Surgeons.


1987 ◽  
Author(s):  
Barry Zuckerman ◽  
◽  
Ralph Hingson ◽  
Deborah Frank ◽  
Hortensia Amaro

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tong-Hui Xie ◽  
Peng Su ◽  
Jian-Guo Hong ◽  
Hui Zhang

Abstract Background Colorectal cancer is a very common malignant tumor worldwide. The clinical manifestations of advanced colorectal cancer include the changes in bowel habits, hematochezia, diarrhea, local abdominal pain and other symptoms. However, the colorectal cancer with an initial symptom of cervical lymph node enlargement is extremely rare. In this article, we report a case of rectal cancer presenting with cervical lymph nodes enlargement as the initial symptom. Case presentation A 57-year-old woman was admitted to our hospital for cervical lymph node enlargement which was accidentally detected during physical examination. Computed tomography scan revealed multiple enlarged lymph nodes in the neck. Cervical ultrasound showed normal thyroid gland and multiple left supraclavicular lymph nodes enlargement. The patient underwent lymph nodes biopsy and pathologic results showed metastatic adenocarcinoma. The subsequent lower gastrointestinal endoscopy revealed a mucosal bulge lesion located at rectus and biopsy revealed adenocarcinoma. The patient underwent rectal cancer resection. She is alive with no evidence of recurrence or new tumors 2 years after surgery. Conclusions Cervical lymph node metastasis is a rare metastatic way in colorectal cancer. This is the first case of rectal cancer presenting with cervical lymph nodes metastases as the initial symptom. Surgical resection combined with postoperative chemotherapy improved long-term prognosis of the patient. This rare metastatic way of rectal cancer should be paid attention for clinicians.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pierre Bourgeois ◽  
E. Peters ◽  
A. Van Mieghem ◽  
A. Vrancken ◽  
G. Giacalone ◽  
...  

AbstractFacial edemas not secondary to surgery and/or radiotherapy for head and neck cancer are relatively uncommon. Our aim is to report a retrospective analysis of the lymphoscintigraphic and SPECT-CT investigations obtained in patients with such facial edema. Retrospective review of exams (planar imagings in all and with SPECT-CT in 5) obtained after the subcutaneous injection of 99mTc HSA Nanosized colloids between the eyebrows in five men and seven women. Four main lymphatic pathways were identified on sequential planar imagings: para-nasal left and right and supra- ocular left and right. For eleven patients, the absence of visualization of lymphatic drainage and/or their delayed appearance correlated well with the localisation of the edematous areas. In two patients with post-traumatic and post- surgical edemas, SPECT-CT showed one deep left sided cervical lymph node (LN) in front of the first cervical vertebra. This lymphoscintigraphic approach represents a simple and valuable way to assess the lymphatic drainage pathways of the face and to establish the diagnosis of facial lymphedema.


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